A trans-omics gene-smoking interaction study of lung cancer based on consortium data [0.03%]
基于联盟数据的肺癌跨国 omics 基因吸烟交互组学研究
Ning Xie,Xiaowen Xu,Yanru Wang et al.
Ning Xie et al.
Rationale: Genetically predicted molecular traits provide a cost-effective approach for identifying biomarkers and uncovering underlying biological mechanisms. We extended this framework to investigate gene-smoking intera...
Spatial Transcriptomics Uncovers Hybrid, Pro-Inflammatory and Pro-Fibrotic Cellular Niches in Pulmonary Granuloma of Patients with Chronic Sarcoidosis [0.03%]
空间转录组学揭示了慢性肉芽肿病患者肺肉芽肿中的杂交、促炎症和促纤维化细胞生态位
Leonard Christian,Hande Yilmaz,Jannik Ruwisch et al.
Leonard Christian et al.
Background: Sarcoidosis is a disease of unknown etiology characterized by the formation of immune cell accumulation (granuloma) in the lung and other tissues. Chronic sarcoidosis may lead to pulmonary fibrosis. ...
Argatroban in Patients with Extracorporeal Membrane Oxygenation-A Randomized Controlled Pilot Trial [0.03%]
艾加曲班用于体外膜肺氧合患者的一项随机对照试点研究
Nina Buchtele,Bernhard Nagler,Peter Schellongowski et al.
Nina Buchtele et al.
Improving Reporting of Withdrawal of Life-Sustaining Treatment in Acute Brain Injury Trials: A Methodologic Imperative [0.03%]
改善急性脑损伤试验中撤除生命维持治疗报告的方法学要求
Shaurya Taran,Alexis F Turgeon,Alexis Steinberg et al.
Shaurya Taran et al.
Ya Luo,Liwan Dai,Xiaowen Wang et al.
Ya Luo et al.
Plasma exchange for severe alveolar hemorrhage in ANCA-associated vasculitis: emulation of a target trial [0.03%]
抗中性粒细胞胞浆抗体相关性血管炎肺泡出血重症患者的血浆置换治疗：目标试验模拟法研究
Anne-Claire Sanna,Ségolène Gendreau,Cyrielle Desnos et al.
Anne-Claire Sanna et al.
Rationale: Patients with severe antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV)-related diffuse alveolar hemorrhage (DAH) face high mortality. In the PEXIVAS trial, plasma exchange (PLEX) did not re...
Polygenic Risk Scores of COPD Predict Lung Function Decline and Early COPD: Results from COSYCONET [0.03%]
基于COSYCONET结果的慢性阻塞性肺疾病多基因风险评分可预测肺功能降低和早期慢阻肺
Hendrik Pott,Roman Martin,Laura Köbbe et al.
Hendrik Pott et al.
Questionable Association between Mechanical Power and Ventilator Induced Lung Injury in ARDS [0.03%]
ARDS中机械做功与呼气末正压损伤的相关性值得商榷
Björn Jonson,Laurent Brochard
Björn Jonson
Electrical impedance tomography-guided PEEP and mortality of patients with the acute respiratory distress syndrome: The EITVent randomized clinical trial [0.03%]
电导性断层扫描技术引导的呼气末正压通气与急性呼吸窘迫综合征患者的死亡率：EITVent随机临床试验
Xueyan Yuan,Ming Zhong,Zhe Li et al.
Xueyan Yuan et al.
Rationale: Physiological studies showed benefits for bedside setting of personalized positive end-expiratory pressure (PEEP) by electrical impedance tomography (EIT), balancing lung overdistension and collapse. ...