Restoring the Sense of Smell: A Systematic Review and Meta-Analysis of Biologic Therapies for Chronic Rhinosinusitis with Nasal Polyps [0.03%]
嗅觉恢复能力：鼻息肉型慢性鼻窦炎生物治疗系统评价和荟萃分析
Christian K Pedersen,Vibeke Backer,Jens Even Tidemandsen et al.
Christian K Pedersen et al.
Purpose of review: Smell loss is among the most debilitating symptoms of chronic rhinosinusitis with nasal polyps (CRSwNP). We aimed to synthesize current evidence on the smell-restoring efficacy of biologics, focusing on...
Jamie L Waldron
Jamie L Waldron
Purpose of this review: We review recent literature on impact of antibiotic allergy during pregnancy, and evidence for management in those self-reporting beta-lactam allergy. ...
Microbial Metabolites in Allergic Diseases: Beyond Short-Chain Fatty Acids [0.03%]
微生物代谢产物与过敏性疾病：短链脂肪酸之外的事物
Jaime Morillas-Armenta,Andrea Macías-Camero,Natalia Rzetecka et al.
Jaime Morillas-Armenta et al.
Purpose of review: The gut microbiota contributes to host homeostasis through the production of bioactive metabolites that regulate immune function. Some of these microbial metabolites, called short-chain fatty acids (SCF...
Mechanisms of Innate Immune Modulation by High-Fat Diet: Implications for Obesity and Asthma [0.03%]
高脂饮食调控固有免疫的机制：对肥胖和哮喘的意义
Heather L Caslin,Jesse W Williams
Heather L Caslin
Purpose of the review: The innate immune system plays a critical role in mediating many of the physiological consequences of high-fat diet consumption. Dietary lipids, and specifically saturated fatty acids like palmitate...
Choice of Mucosa Removal in Endoscopic Sinus Surgery for Chronic Rhinosinusitis with Nasal Polyps: A Systematic Review and Network Meta-Analysis [0.03%]
鼻息肉慢性鼻窦炎内窥镜鼻窦手术粘膜切除术方式的选择系统评价和网络 meta 分析
Ying-Xing Wu,Ke-Zhang Zhu,Ming Zeng et al.
Ying-Xing Wu et al.
Purpose of review: The optimal management of mucosal tissues during endoscopic sinus surgery (ESS) for chronic rhinosinusitis with nasal polyps (CRSwNP) remains controversial. This systematic review and network meta-analy...
Dendritic Cells: at the Crossroads between Oral Tolerance and Food Allergy [0.03%]
树突状细胞在口腔耐受与食物过敏的交叉路口
Kelly E Butler,Elise G Liu
Kelly E Butler
Purpose of review: Dendritic cells are specialized antigen presenting cells that bridge innate and adaptive immune responses. Here, we focus on the role of dendritic cells in food tolerance and food allergy pathogenesis a...
Using the Electronic Health Record to Facilitate Drug Allergy Delabeling [0.03%]
利用电子健康记录简化药物过敏标签删除流程
Matthew J Molloy,Adam P Yan,Averi E Wilson et al.
Matthew J Molloy et al.
Purpose of review: There is a growing number of allergy delabeling programs across diverse clinical specialties and care settings. The electronic health record (EHR) can be leveraged to facilitate allergy delabeling. The ...
What is New in Contact Allergy To Cosmetics for Physicians, Cosmetologists, and Cosmetic Users? [0.03%]
化妆品接触性过敏的新知：对医师、化妆师和化妆品使用者的建议
Thanisorn Sukakul,Cecilia Svedman
Thanisorn Sukakul
Purpose of review: This paper aims to evaluate the burden of contact allergy caused by cosmetic products, identifying the key allergens involved and examining recent regulatory and diagnostic developments. The review addr...
Organotypic Airway Models Derived from Primary Human Nasal Epithelial Cells [0.03%]
基于人原代鼻上皮细胞的器官型呼吸道模型
Jing Liu,Hsiao Hui Ong,Kun Qu et al.
Jing Liu et al.
Purpose of the review: The respiratory system is essential for gas exchange and immune defense but is highly susceptible to pathogens and harmful agents. Chronic rhinosinusitis, asthma, COPD, and emerging viral infections...
Yangxue Fu,Hao Chen,Jin Liu et al.
Yangxue Fu et al.
Purpose of review: This review highlights current limitations of allergen-specific immunotherapy (AIT) methods and introduces microneedles (MNs) as an innovative transdermal platform to enhance AIT safety, efficacy, and p...