Nadia Khoury,Anne Carol Goldberg
Nadia Khoury
Clinical trials have demonstrated the benefit of reduction of low-density lipoprotein (LDL) cholesterol levels in the prevention of atherosclerotic cardiovascular disease. Evidence is less robust for the effect of reduction of triglyceride ...
Kiran Musunuru
Kiran Musunuru
Pharmacogenomics holds the promise of transforming patient care by allowing providers to tailor therapy to each individual patient based on his or her genetic information. Although no established pharmacogenomic applications in cardiovascul...
Jacqueline L Green,Fadi J Sawaya,Allen L Dollar
Jacqueline L Green
There is increasing evidence that restricting caloric intake may have considerable health benefits in humans. Significant evidence in non-primate animals demonstrates that caloric restriction increases average and maximal life span. However...
Henry A Tran,Arthur Schwartzbard,Howard S Weintraub
Henry A Tran
The pathogenesis of cardiovascular disease is a complex and dynamic process. The renin-angiotensin-aldosterone system (RAAS) is a potent and powerful mediator in the homeostasis of the cardiovascular and renal systems. RAAS blockade via ang...
Basilar branch occlusion [0.03%]
基底动脉分支卒中
Jaime Gállego Culleré,María Elena Erro Aguirre
Jaime Gállego Culleré
During the past few years, the branch syndromes have been ascribed to pontine lesions, and the development of neuroimaging techniques has renewed the interest in exploring their clinical-radiological correlation. Brain imaging via MRI has h...
Use of telemedicine and helicopter transport to improve stroke care in remote locations [0.03%]
远程使用远程医疗和直升机转送改善卒中救治
Mihaela Saler,Jeffrey A Switzer,David C Hess
Mihaela Saler
Intravenous recombinant tissue plasminogen activator is the only medication approved by the US Food and Drug Administration for treatment of acute stoke. Despite established efficacy, less than 3% of stroke patients receive treatment, and t...
Medico-legal aspects of using tissue plasminogen activator in acute ischemic stroke [0.03%]
急性缺血性卒中使用组织型纤溶酶原激活物的医事法律问题
Nhu T Bruce,William P Neil,Justin A Zivin
Nhu T Bruce
Intravenous alteplase or tissue plasminogen activator (tPA) has been the standard of care with proven efficacy for acute ischemic stroke for over a decade. Despite this, only a small fraction of potentially eligible stroke patients receive ...
Hyung-Min Kwon,Yong-Seok Lee
Hyung-Min Kwon
Dolichoectasia is a dilatation and elongation of the arteries, usually affecting intracranial basilar and vertebral arteries. It may cause posterior circulation stroke or transient ischemic attacks independent of atherosclerotic disease. Co...
Acute Decompressive Hemicraniectomy to Control High Intracranial Pressure in Patients with Malignant MCA Ischemic Strokes [0.03%]
急性减压半侧颅骨切除术控制恶性大脑中动脉梗死患者的高颅内压
David Z Wang,Deepak S Nair,Arun V Talkad
David Z Wang
Malignant middle cerebral artery (MCA) infarction occurs in about 10% of all patients with supratentorial ischemic strokes. The infarction involves the entire MCA territory. Due to the consequences of severe brain edema, brain herniation, e...
Venous angiomas [0.03%]
静脉血管瘤
Sepideh Amin-Hanjani
Sepideh Amin-Hanjani
Venous angiomas are currently widely referred to as developmental venous anomalies (DVAs), reflecting the prevailing concept that they represent anomalous, but functional, venous channels within the brain parenchyma. Although DVAs are not i...