Update on cytomegalovirus infections of the gastrointestinal system in solid organ transplant recipients [0.03%]
固体器官移植受者胃肠道巨细胞病毒感染的最新研究进展
Tracy L Lemonovich,Richard R Watkins
Tracy L Lemonovich
Cytomegalovirus (CMV) infection of the gastrointestinal tract is the most common manifestation of tissue-invasive CMV disease, and is a significant cause of morbidity and mortality in the solid organ transplantation (SOT) recipient. In addi...
Richard R Watkins
Richard R Watkins
Gastrointestinal illness following natural disasters is a common occurrence and often results from the disruption of potable water supplies. The risk for outbreaks of gastrointestinal illness is higher in developing countries because of few...
James A Platts-Mills,Darwin J Operario,Eric R Houpt
James A Platts-Mills
Determining the microbiologic etiology of enteric infection remains an elusive goal. Conventional approaches, including culture, microscopy, and antigen-based tests have significant limitations such as limit of detection and the need for mu...
Cornelius J Clancy,M Hong Nguyen
Cornelius J Clancy
Skin toxicity due to voriconazole is well recognized. Recently, several series have reported skin cancer, particularly cutaneous squamous cell carcinoma (C-SCC), following photosensitivity reactions among patients receiving long-term vorico...
Diagnosis and antimicrobial therapy of lung infiltrates in febrile neutropenic cancer patients [0.03%]
发热性中性粒细胞减少癌症患者的肺浸润的诊断和抗菌治疗
Georg Maschmeyer
Georg Maschmeyer
Pulmonary infiltrates develop in up to 25% of febrile neutropenic patients and are frequently refractory to broad-spectrum antibacterial therapy. Etiologically, Aspergillus spp., Pneumocystis jiroveci, multi-resistant Gram-negative rods as ...
Assessing responses to treatment of opportunistic mycoses and salvage strategies [0.03%]
评估机会性真菌病的治疗反应及补救策略
Baldeep Wirk,John R Wingard
Baldeep Wirk
Invasive fungal disease (IFD) in immunocompromised patients remains a major cause of morbidity and mortality and there is a pressing need for studies of novel antifungal agents and strategies to improve outcomes. Trial design details often ...
Current role of echinocandins in the management of invasive aspergillosis [0.03%]
棘白菌素类抗真菌药在侵袭性曲霉病治疗中的作用
Małgorzata Mikulska,Claudio Viscoli
Małgorzata Mikulska
Echinocandins are parenteral antifungals with a unique site of action targeting the cell wall synthesis. There are three molecules available, anidulafungin, caspofungin, and micafungin, which have fungicidal and fungistatic activity against...
Biopsy procedures for molecular tissue diagnosis of invasive fungal infections [0.03%]
侵袭性真菌感染分子组织病理诊断的活检方法
Cornelia Mrazek,Cornelia Lass-Flörl
Cornelia Mrazek
The incidence of invasive fungal infections (IFI) has increased substantially and the epidemiology has changed dramatically in recent years. Candida albicans is still most important, but non-albicans species, Aspergillus species, Glomeromyc...
Secondary Antifungal Prophylaxis in Hematopoietic Stem Cell Transplantation (HSCT)/Acute Leukemia Patients [0.03%]
造血干细胞移植/急性白血病患者 secondary antifungal prophylaxis的研究
Jean El Cheikh
Jean El Cheikh
In this review, the role of secondary antifungal prophylaxis (SAP) in prevention of invasive fungal infections (IFIs) in patients with leukemia and in those receiving allogeneic hematopoietic stem cell transplantation (allo-HSCT) is discuss...
Paul Bowyer,Caroline B Moore,Riina Rautemaa et al.
Paul Bowyer et al.
Oral triazole therapy is well established for the treatment of invasive aspergillosis (IPA), allergic aspergillosis (ABPA), and chronic pulmonary aspergillosis (CPA), and is often long-term. Resistance to triazole azole antifungal drugs in ...