Prosthetic joint infections [0.03%]
人工关节感染
Saima Aslam,Rabih O Darouiche
Saima Aslam
Prosthetic joint infections represent a major therapeutic challenge for both healthcare providers and patients. This article reviews the predisposing factors, pathogenesis, microbiology, diagnosis, treatment, and prophylaxis of prosthetic j...
Chronic osteomyelitis [0.03%]
慢性骨髓炎
Ilker Uçkay,Kheeldass Jugun,Axel Gamulin et al.
Ilker Uçkay et al.
Chronic osteomyelitis is a multifaceted bacterial infection with common features. It absolutely requires surgery for remission. The duration and form of concomitant administration of antibiotic agents for adult patients is still based on ex...
HMG-CoA Reductase Inhibitors for Prevention and Treatment of Severe Sepsis [0.03%]
他汀类药物在防治重症脓毒症中的作用
Joel D Mermis,Steven Q Simpson
Joel D Mermis
HMG-CoA reductase inhibitors, or statins, are among the most commonly prescribed pharmaceuticals in the world, especially among the elderly. The remarkable conjuncture of this fact with the rising incidence of severe sepsis among people ove...
Ralf-Peter Vonberg,Petra Gastmeier
Ralf-Peter Vonberg
There is strong evidence that preoperative nasal S. aureus screening/decolonization will significantly reduce surgical site infections (SSIs) after joint prostheses implantation. There is some evidence that antibiotic-containing bone cement...
Federico Nalesso,Zaccaria Ricci,Claudio Ronco
Federico Nalesso
Acute kidney injury (AKI) often complicates sepsis, leading to greater complexity and a worsening prognosis. Advances in the clinical management of sepsis may have secondary benefits with respect to renal outcomes. In critically ill patient...
Subcutaneous fungal infections [0.03%]
皮下真菌感染
Ricardo M La Hoz,John W Baddley
Ricardo M La Hoz
Subcutaneous mycoses are common in tropical and subtropical regions of the world. These infections have multiple features in common, including similar epidemiology, mode of transmission, indolent chronic presentation with low potential for ...
John H Boyd
John H Boyd
Serious infection and the patient's response (sepsis) is a serious health problem that, even today, is associated with a mortality rate of 30 %-50 %. The phases of severe sepsis include an early hyperinflammatory response to pathogens and a...
Balamuthia mandrillaris amoebic encephalitis: an emerging parasitic infection [0.03%]
狒狒猕猴囊尾蚴amoebic脑病：一种新兴的寄生虫感染疾病
Francisco G Bravo,Carlos Seas
Francisco G Bravo
Balamuthia mandrillaris is a free living amoeba that can be isolated from soil. It is an emerging pathogen causing skin lesions as well as CNS involvement with a fatal outcome if untreated. The infection has been described more commonly in ...
Vaccination against rheumatic heart disease: a review of current research strategies and challenges [0.03%]
风湿性心脏病的疫苗预防：当前研究策略与挑战综述
Manisha Pandey,Michael R Batzloff,Michael F Good
Manisha Pandey
Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) are major health problems in many developing countries and Indigenous populations of developed countries. ARF and RHD are sequelae resulting from an infection of Streptococcus py...
Rabies: still a uniformly fatal disease? Historical occurrence, epidemiological trends, and paradigm shifts [0.03%]
狂犬病：一种仍会致死的疾病吗？历史发生情况、流行趋势与范式转变
Henry M Feder Jr,Brett W Petersen,Kis L Robertson et al.
Henry M Feder Jr et al.
Rabies has the highest case fatality of any infectious disease. Pathobiological and clinical insights have questioned the assertion that death is inevitable after onset of acute encephalomyelitis. Relying upon national laboratory-based surv...