Marina S Morgan
Marina S Morgan
With four types of necrotizing fasciitis (NF) now recognized, the diagnosis and management of NF becomes more challenging as physicians face more unusual pathogenic and atypical presentations. With few published guidelines and little eviden...
When and how to cover for fungal infections in patients with severe sepsis and septic shock [0.03%]
严重脓毒症和感染性休克患者抗真菌保护性治疗的时机及方法之探讨
Nicolas Allou,Jerome Allyn,Philippe Montravers
Nicolas Allou
Candida species remain the most frequently isolated fungi in intensive care unit (ICU) patients with severe sepsis or septic shock. Delayed antifungal therapy in these patients is a recognized risk factor for mortality. However, the diagnos...
Isaac Thomsen,C Buddy Creech
Isaac Thomsen
Acute hematogenous osteomyelitis is a common disease that affects previously healthy children of all age groups. Despite its importance, there are limited data in the current literature to guide many aspects of the diagnosis and therapy of ...
Soft tissue infections caused by marine bacterial pathogens: epidemiology, diagnosis, and management [0.03%]
海洋细菌病原体所致软组织感染：流行病学、诊断和治疗
Renato Finkelstein,Ilana Oren
Renato Finkelstein
Skin and soft tissue infections (SSTIs) are one of the most common infection syndromes and may be caused by a large number of microorganisms. Some principles of aquatic injuries are different than those of land-based trauma. Wounds sustaine...
Sumeet Chander,Gerald Coakley
Sumeet Chander
Septic arthritis is a common rheumatological emergency requiring prompt diagnosis and treatment, since delays in management can lead to high morbidity and mortality. In this review article, we discuss the epidemiology and recent advances in...
Community-Acquired Methicillin-Resistant Staphylococcus aureus Skin and Soft Tissue Infections: Management and Prevention [0.03%]
社区获得性耐甲氧西林金黄色葡萄球菌皮肤和软组织感染的诊治与预防对策
Luke F Chen,Cody Chastain,Deverick J Anderson
Luke F Chen
Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) was a rare phenomenon until the past decade; now CA-MRSA is endemic in many communities and is the most common cause of skin and soft tissue infections presenting to e...
Rajesh K Aneja,Ruby Varughese-Aneja,Carol G Vetterly et al.
Rajesh K Aneja et al.
Severe sepsis accounts for nearly 4,500 deaths (mortality rate 10%), and is responsible for nearly $2 billion annual healthcare expenditure in the United States. Early and speedy treatment of critically ill septic patients can halt or reduc...
Guillain-barré syndrome following influenza vaccination: causal or coincidental? [0.03%]
流感疫苗接种后的吉兰-巴雷综合征：因果关系还是偶然巧合？
James J Sejvar,Dina Pfeifer,Lawrence B Schonberger
James J Sejvar
In 1976, the emergence of a new swine-origin influenza virus prompted concerns about an impending influenza pandemic. Although the outbreak never materialized, the epidemiological link between Guillain-Barre syndrome, a potentially severe p...
Meningococcal disease: shifting epidemiology and genetic mechanisms that may contribute to serogroup C virulence [0.03%]
脑膜炎奈瑟菌病：不断变化的流行病学以及可能造成C群毒力的遗传机制
Jessica R Macneil,Jennifer D Thomas,Amanda C Cohn
Jessica R Macneil
During the past decade, monovalent serogroup C and quadrivalent (serogroups A, C, W135, Y) meningococcal vaccination programs have been introduced in multiple industrialized countries. Many of these programs have been successful in reducing...
Sachin Kedar,Joseph R Berger
Sachin Kedar
Progressive multifocal leukoencephalopathy (PML) is a rare but devastating neurologic disease that affects the immunosuppressed population. The etiologic agent is a polyomavirus, JC virus-a double-stranded DNA virus with a high prevalence o...