Gary L Davis,William L Roberts
Gary L Davis
The Baby Boomer generation is composed of 78 million Americans who are just beginning to reach their retirement years. Most Boomers have at least one chronic health problem, and these significantly increase the expense of providing medical ...
Beyond acid suppression: new pharmacologic approaches for treatment of GERD [0.03%]
抑酸以外的新药理学方法治疗胃食管反流病(GERD)
Paul Kuo,Richard H Holloway
Paul Kuo
Proton pump inhibitors are highly successful in treating gastroesophageal reflux disease, but a significant proportion of patients have persistent symptoms from weakly or nonacidic reflux. Transient lower esophageal sphincter relaxation (TL...
Safety of proton pump inhibitors: current evidence for osteoporosis and interaction with antiplatelet agents [0.03%]
质子泵抑制剂的安全性：目前关于防治骨质疏松症和与抗血小板药物相互作用的证据
David A Johnson
David A Johnson
Proton pump inhibitors (PPIs) are commonly used in millions of patients. Despite the widespread usage and favorable safety profile, much attention has focused recently on potential adverse events associated with use. One area of particular ...
Nanda Kerkar,Tamir Miloh
Nanda Kerkar
Sclerosing cholangitis is a rare progressive cholestatic liver disease affecting the biliary tract. It may be associated with other diseases including autoimmune hepatitis, immunodeficiencies, cystic fibrosis, and sickle cell disease. Scler...
Esophageal stents for severe strictures in young children: experience, benefits, and risk [0.03%]
儿童严重食管狭窄的支架治疗：经验、益处和风险
Robert E Kramer,J Antonio Quiros
Robert E Kramer
The use of esophageal stents has been commonplace in adults for many years and for a variety of indications, including palliative care for malignant lesions involving the esophagus. The use of esophageal stents in the pediatric population, ...
Veerle Mertens,Lieven Dupont,Daniel Sifrim
Veerle Mertens
Lung transplantation has become a valuable treatment for end-stage pulmonary disorders in an attempt to improve quality of life and extend survival. Development of chronic rejection, also known as bronchiolitis obliterans syndrome (BOS), is...
Manoj Shah,Marquelle Klooster,George Yanni et al.
Manoj Shah et al.
Gastrojejunal (GJ) tubes are increasingly used for enteral feeding in children in whom gastric feeding either is not tolerated or is contraindicated. The most common complications associated with GJ tube use are mechanical failure (clogging...
Etiology of esophageal atresia and tracheoesophageal fistula: "mind the gap" [0.03%]
食道闭锁与气管食道瘘的病因：“注意缺口”
Elisabeth M de Jong,Janine F Felix,Annelies de Klein et al.
Elisabeth M de Jong et al.
Esophageal atresia and tracheoesophageal fistula (EA/TEF) are major congenital malformations affecting 1:3500 live births. Current research efforts are focused on understanding the etiology of these defects. We describe well-known animal mo...
Jeffrey A Blatnik,Todd A Ponsky
Jeffrey A Blatnik
The field of pediatric surgery has undergone numerous changes throughout the past few years. When laparoscopic surgery was introduced, pediatric surgeons were reluctant to change their practice because many of the instruments were not appro...
Adrian N Holm,Henning Gerke
Adrian N Holm
Current methods for imaging the biliary tree include ultrasound, CT, MRI, endoscopic retrograde cholangiography, and endoscopic ultrasound (EUS). Bile duct abnormalities may be identified during evaluation of patient symptoms or laboratory ...