Dawn M Wiese,David A Schwartz
Dawn M Wiese
Perianal Crohn’s Disease (CD) is a significant cause of morbidity in CD patients. Accurate identification of perianal involvement requires advanced imaging techniques in addition to physical exam. Treatment of the disease is aimed at impro...
Intraductal papillary mucinous neoplasms of the pancreas: making a disposition using the natural history [0.03%]
胰腺导管内乳头状黏液性肿瘤的自然史及其临床处置策略
L William Traverso,Toshiyuki Moriya,Yasushi Hashimoto
L William Traverso
The process of Intraductal papillary mucinous neoplasms (IPMN) follows the adenoma-to-carcinoma sequence. If it progresses to malignancy about 5 years is required. Even though the process is slow IPMN provides the clinician with the opportu...
John M Vierling
John M Vierling
Autoimmune hepatitis is a chronic liver disease characterized by elevated aminotransferase levels, autoantibodies, increased γ-globulin or IgG levels and biopsy evidence of interface hepatitis. Recent advances include new practice guidelin...
Mohammad A B Al-Freah,Zeino Zeino,Michael A Heneghan
Mohammad A B Al-Freah
Chronic kidney disease represents a global health problem. Chronic hepatitis C virus (HCV) infection is prevalent in patients with end stage renal disease (ESRD) on hemodialysis (HD) and in renal transplant recipients with significant impac...
Resistance-associated variants in chronic hepatitis C patients treated with protease inhibitors [0.03%]
丙型肝炎患者接受蛋白酶抑制剂治疗后的耐药相关变异分析
Maya Gambarin-Gelwan,Ira M Jacobson
Maya Gambarin-Gelwan
Direct-acting antiviral agents in combination with pegylated interferon (PEG-IFN) and ribavirin (RBV) significantly improve sustained virologic response rate and reduce duration of therapy among both treatment-naïve and treatment-experienc...
James E Nelson,Heather Klintworth,Kris V Kowdley
James E Nelson
Non-Alcoholic Fatty Liver Disease (NAFLD) is a common worldwide clinical and major public health problem affecting both adults and children in developed nations. Increased hepatic iron stores are observed in about one-third of adult NAFLD p...
Ashley Barnabas,Roger W Chapman
Ashley Barnabas
While many therapeutic agents have been evaluated in Primary Sclerosing Cholangitis (PSC), none have been shown in controlled trials to modify the course of disease. The bile acid ursodeoxycholic acid (UDCA) has been widely used in the trea...
Alessandra Mangia,Leonardo Mottola
Alessandra Mangia
The HCV genotype will remain an important, independent pre-treatment predictor of virological response. While direct acting antivirals (DAA) will improve in the coming months the rates of virological response in patients with HCV-1, the dev...
Lei Yuan Lim,Naga Chalasani
Lei Yuan Lim
Vitamin D is now widely recognized to have multiple extraskeletal health functions. The liver is one of the major organs involved in its metabolism. Recent studies have demonstrated a very high prevalence of vitamin D deficiency and insuffi...
Sudeep Tanwar,Geoffrey Dusheiko
Sudeep Tanwar
Hepatitis B may cause a varying spectrum of diseases ranging from an asymptomatic or mild anicteric acute illness, to severe or fulminant hepatitis. Similarly, the outcome of chronic hepatitis B is variable. Viral factors associated with ou...