Daniel DAgostino,Silvia Diaz,Maria Camila Sanchez et al.
Daniel DAgostino et al.
Although the etiologies of pediatric acute liver failure (ALF) are diverse, ultimate pathophysiologic pathways and management challenges for these disorders, usually lethal in the pre-transplant era, are similar. This review considers parti...
Advanced endoscopic imaging for Barrett's Esophagus: current options and future directions [0.03%]
巴雷特食管的高级内镜影像技术:现有选项与未来方向
Michelle H Lee,Kristin Buterbaugh,Rebecca Richards-Kortum et al.
Michelle H Lee et al.
Barrett's esophagus is the precursor to esophageal adenocarcinoma, one of the most rapidly increasing cancers in the United States. Given the poor prognosis of late-stage adenocarcinoma, endoscopic surveillance is recommended for subjects w...
Frank Zerbib,Stanislas Bruley des Varannes,Mireille Simon et al.
Frank Zerbib et al.
Functional heartburn (FH) is a functional gastro-intestinal disorder characterized by symptoms of heartburn not related to gastro-esophageal reflux. The absence of evidence of reflux-related symptoms relies on absence of esophagitis at endo...
Fernando Alvarez
Fernando Alvarez
Relatively few pediatric donors are available in relation to the number of children waiting for a liver transplant. This limited number of pediatric donor livers leads to the use of adult livers, usually requiring more complex portal vein (...
How does knowledge from translational research impact our clinical care of pediatric inflammatory bowel disease patients? [0.03%]
转化研究所得的知识如何影响我们对儿童炎症性肠病患者的临床护理?
Lee A Denson
Lee A Denson
Recent translational studies have provided new insights into pathogenesis, disease behavior, and treatment responses in pediatric Inflammatory Bowel Disease (IBD). Registry studies have identified distinct clinical phenotypes with increasin...
Eosinophilic esophagitis: allergic contribution, testing, and management [0.03%]
嗜酸细胞性食管炎:过敏因素、检测和处理方法
Amindra A Arora,Catherine R Weiler,David A Katzka
Amindra A Arora
Both basic science and clinical data indicate a strong role for allergy as a cause of eosinophilic esophagitis. As a result, one of the desired goals of therapy is identification and elimination of food antigens that trigger the allergic in...
Stefan Niebisch,Jeffrey H Peters
Stefan Niebisch
Rudolph Nissen firstly implemented the idea of surgical treatment of gastroesophageal reflux more than 55 years ago. Today, laparoscopic fundoplication has become the surgical "golden standard" for the treatment of GERD. However, the initia...
Clinical implications of molecular changes in pediatric Barrett's esophagus [0.03%]
儿科巴雷特食管分子改变的临床意义
Licia Pensabene,Marta C Cohen,Michael Thomson
Licia Pensabene
Barrett's esophagus (BE) is a preneoplastic condition that predisposes to esophageal adenocarcinoma. Although data on the occurrence of BE in children are limited, recent studies have suggested an increase in the pediatric population. BE is...
George Rossidis,Steven J Hughes
George Rossidis
Minimally invasive surgery has been widely accepted as an alternative to conventional open surgery in many gastrointestinal fields and is now considered the standard of care in bariatric surgery as well as oncologic surgery of the colon and...
Stephen F Murphy,John H Kwon,David L Boone
Stephen F Murphy
Technological and conceptual advances in inflammatory bowel disease research have uncovered new mechanisms that contribute to the pathogenesis of these disorders. It is becoming increasingly clear that the microbiota of the gut and the resp...