Roxanne Radi,Harriet Huang,Jason Rivera et al.
Roxanne Radi et al.
YES. Low-dose naltrexone is as effective as amitriptyline in the treatment of painful diabetic neuropathy and has a superior safety profile (strength of recommendation [SOR], B; single randomized controlled trial [RCT]). Low-dose naltrexone...
Randomized Controlled Trial
The Journal of family practice. 2023 Sep;72(7):320-321. DOI:10.12788/jfp.0654 2023
Daniel Holligan,Roxanne Radi,Corey Lyon
Daniel Holligan
While treatment with metformin or lifestyle modification reduces risk for T2D in patients with prediabetes, neither intervention ultimately offers a mortality benefit.
Kimberly R Dong,Sarah Eustis,Kerri Hawkins et al.
Kimberly R Dong et al.
The evidence supports patient use of this simple equation to evaluate the nutrition labels of packaged carbohydrate foods in the grocery aisle in order to make healthier decisions.
Shayan Owji,Chibuzo Aguwa,Joseph Han et al.
Shayan Owji et al.
This study demonstrated the value of using electrical impedance spectroscopy in primary care to manage and diagnose pigmented skin lesions.
Danielle Christifano,Lara Bennett
Danielle Christifano
The developmental origins of health and disease (DOHaD) hypothesis suggests prenatal nutrition sets the stage for the developing brain, with effects that last into adulthood. Macronutrient and micronutrient requirements increase in pregnanc...
Acute Pain in Perspective [0.03%]
从整体观点认识急性疼痛
Bill McCarberg
Bill McCarberg
Acute pain is a common and nearly universal experience that usually has a sudden onset and is limited in duration. It is a normal physiologic response to a noxious stimulus that can become pathologic if untreated or not treated effectively....
John E Anderson,Javed Butler,Andrei V Alexandrov
John E Anderson
Stroke is a significant cause of mortality worldwide, and diabetes is an independent risk factor for ischemic stroke occurrence and recurrence. Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) lower the risk of ischemic stroke through ...
Use of ICS and Fast-Acting Bronchodilators in Asthma: Past, Present, and Future [0.03%]
哮喘的吸入皮质激素及速效支气管舒张剂的过去、现在和未来
Neil Skolnik,Marissa Norden,Njira Lugogo et al.
Neil Skolnik et al.
Primary care practitioners (PCPs) play a key role in asthma management since most patients with asthma are treated in primary care settings. Despite continual advances in asthma care, important practice gaps remain, and the high burden of a...
Barbara Yawn
Barbara Yawn
New updates in the Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2023 report include major changes to initial disease assessment and pharmacologic therapy, highlighting the clinical relevance of exacerbations. The updated GO...
Steven Edelman
Steven Edelman
Type 1 diabetes (T1D) is an autoimmune disease mediated by T cells that target and destroy insulin-producing beta cells. Individuals with genetic risk of T1D will progress at variable rates through 3 stages of immune activation and developm...