Eiffel-by-Night Sign [0.03%]
埃菲尔之夜标志
Kundian Guo,Zhen Hong
Kundian Guo
CRISPR-Cas9 Gene Editing with Nexiguran Ziclumeran for ATTR Cardiomyopathy [0.03%]
用于ATTR性心肌病的Nexigauran Ziclumeran CRISPR-Cas9基因编辑疗法
Marianna Fontana,Scott D Solomon,Jessica Kachadourian et al.
Marianna Fontana et al.
Background: Transthyretin amyloidosis with cardiomyopathy (ATTR-CM) is a progressive, often fatal disease. Nexiguran ziclumeran (nex-z) is an investigational therapy based on CRISPR-Cas9 (clustered regularly interspaced s...
Yufang Bi,Mian Li,Yan Liu et al.
Yufang Bi et al.
Background: Effective targets for systolic blood-pressure control in patients with type 2 diabetes are unclear. Methods: We enrolled pa...
Tirzepatide for Heart Failure with Preserved Ejection Fraction and Obesity [0.03%]
心力衰竭伴射血分数保留和肥胖患者的Tirzepatide治疗
Milton Packer,Michael R Zile,Christopher M Kramer et al.
Milton Packer et al.
Background: Obesity increases the risk of heart failure with preserved ejection fraction. Tirzepatide, a long-acting agonist of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptors, causes co...
Sanjit S Jolly,Marc-André d&#x;Entremont,Shun Fu Lee et al.
Sanjit S Jolly et al.
Background: Inflammation is associated with adverse cardiovascular events. Data from recent trials suggest that colchicine reduces the risk of cardiovascular events. ...
Oussama M Wazni,Walid I Saliba,Devi G Nair et al.
Oussama M Wazni et al.
Background: Oral anticoagulation is recommended after ablation for atrial fibrillation among patients at high risk for stroke. Left atrial appendage closure is a mechanical alternative to anticoagulation, but data regardi...
Catheter Ablation or Antiarrhythmic Drugs for Ventricular Tachycardia [0.03%]
室性心动过速的导管消融治疗与抗心律失常药物治疗比较研究
John L Sapp,Anthony S L Tang,Ratika Parkash et al.
John L Sapp et al.
Background: Patients with ventricular tachycardia and ischemic cardiomyopathy are at high risk for adverse outcomes. Catheter ablation is commonly used when antiarrhythmic drugs do not suppress ventricular tachycardia. Wh...
Mind the Sentinel - Applying Patient-Safety Paradigms to Clinician Well-Being [0.03%]
警钟长鸣——从患者安全角度审视临床医生的福祉问题
Catherine A Humikowski
Catherine A Humikowski
Ravi Savarirayan,Josep Maria De Bergua,Paul Arundel et al.
Ravi Savarirayan et al.
Background: Achondroplasia is a genetic skeletal condition that results in disproportionately short stature and medical complications throughout life. Infigratinib is an orally bioavailable FGFR1-3 selective tyrosine kina...
Katherine A Koh
Katherine A Koh