Vinay Prasad,Martin A Makary
Vinay Prasad
Craig LaForce,Frank Albers,Anna Danilewicz et al.
Craig LaForce et al.
Background: As-needed use of albuterol-budesonide has been shown to result in a significantly lower risk of severe asthma exacerbation than as-needed use of albuterol alone among patients with moderate-to-severe asthma. D...
Toby M Maher,Shervin Assassi,Arata Azuma et al.
Toby M Maher et al.
Background: Nerandomilast (BI 1015550) is an orally administered preferential inhibitor of phosphodiesterase 4B with antifibrotic and immunomodulatory properties. Nerandomilast has been shown to slow the progression of id...
Progress through Persistence - Turning the Page in Pulmonary Fibrosis Clinical Trials [0.03%]
坚持不懈，推进特发性肺纤维化临床试验向前发展
Joyce S Lee
Joyce S Lee
Luca Richeldi,Arata Azuma,Vincent Cottin et al.
Luca Richeldi et al.
Background: Nerandomilast (BI 1015550) is an orally administered preferential inhibitor of phosphodiesterase 4B with antifibrotic and immunomodulatory effects. In a phase 2 trial involving patients with idiopathic pulmona...
Methotrexate as Initial Therapy for Symptomatic Pulmonary Sarcoidosis? [0.03%]
甲氨蝶呤作为肉芽肿性肺部疾病初始治疗药物？
Robert P Baughman,Elyse E Lower
Robert P Baughman
Michael K Gould
Michael K Gould
Navigational Bronchoscopy or Transthoracic Needle Biopsy for Lung Nodules [0.03%]
导航支气管镜或经皮肺穿刺对肺癌患者的诊断价值比较
Robert J Lentz,Katherine Frederick-Dyer,Virginia B Planz et al.
Robert J Lentz et al.
Background: Each year, millions of pulmonary nodules are identified incidentally or through lung cancer screening, and many involve biopsy to distinguish cancer from benign processes. Both navigational bronchoscopy and co...
First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate [0.03%]
肺部肉芽肿的一线治疗：美洛昔康与泼尼松龙的对比研究
Vivienne Kahlmann,Montse Janssen Bonás,Catharina C Moor et al.
Vivienne Kahlmann et al.
Background: Prednisone is currently recommended as the first-line treatment for pulmonary sarcoidosis but is associated with many side effects. Methotrexate, which is recommended as a second-line treatment, appears to hav...
Kiran Musunuru,Sarah A Grandinette,Xiao Wang et al.
Kiran Musunuru et al.
Base editors can correct disease-causing genetic variants. After a neonate had received a diagnosis of severe carbamoyl-phosphate synthetase 1 deficiency, a disease with an estimated 50% mortality in early infancy, we immediately began to d...