Inclisiran in Patients with CKD: Post Hoc Pooled Analysis of Three Phase 3 Trials [0.03%]
CKD患者inclisiran三期临床试验的预设事后汇总分析
Ulf Landmesser,Kausik K Ray,Frederick J Raal et al.
Ulf Landmesser et al.
Background: Lowering low-density lipoprotein cholesterol (LDL cholesterol) reduces the risk of atherosclerotic cardiovascular disease in patients with chronic kidney disease (CKD). The efficacy and safety of inclisiran ve...
Direct Measurement of GFR: Who, When, and How?: A Practical Approach Emphasizing Iohexol Plasma Clearance [0.03%]
直接测量GFR：谁？何时？如何？：一种实用的方法，着重于碘海醇血浆清除率
Elke Schaeffner,Natalie Ebert,Christine A White
Elke Schaeffner
Knowledge of kidney function is a key component for diagnosing chronic kidney disease (CKD) and initiating treatment. The estimated GFR (eGFR), which is most commonly used in clinical practice as an approximation of kidney function, is the ...
Therapeutic Potential of HSP90 Inhibitor 17-DMAG in Regulating METTL3 for Kidney Fibrosis Treatment [0.03%]
HSP90抑制剂17-DMAG通过调控METTL3治疗肾脏纤维化的潜力研究
Soo Min Lee,Myoung Seok Lee,Hae Rim Jung et al.
Soo Min Lee et al.
Background: Kidney fibrosis is a major pathological feature of chronic kidney disease (CKD), characterized by excessive deposition of extracellular matrix proteins, leading to progressive loss of kidney function. N6-methy...
Kidney Function and Blood and Cerebrospinal Fluid Biomarkers in Alzheimer's Disease and Related Dementias: Systematic Review and Meta-Analysis [0.03%]
阿尔茨海默病及相关痴呆的肾功能和血浆及脑脊液生物标志物：系统评价和meta分析
Yuwei Lin,Zaixin Zhao,Nanbo Zhu et al.
Yuwei Lin et al.
Background: Studies have shown that low kidney function may link to elevated Alzheimer's disease and related dementia fluid biomarkers, but the results are not consistent. This systematic review and meta-analysis aimed to...
Kyle Feola,Andrea H Venable,Mina Rasouli et al.
Kyle Feola et al.
Background: Abnormal renal fatty acid oxidation in kidney disease suggests that dysregulated metabolism is a key component of kidney disease pathogenesis. While the liver is the main ketogenic organ, the rate-limiting enz...
Fan-Chi Chang,Takuji Enya,Tomokazu Souma
Fan-Chi Chang
Ferroptosis is a distinct necrotic form of regulated cell death caused by a breakdown in membrane redox homeostasis. Accumulating evidence highlights a central role for ferroptosis in both acute and chronic kidney diseases, with proximal tu...
Jennifer H Yo,Yuanhang Yang,Aurora Caldinelli et al.
Jennifer H Yo et al.
Background: Preeclampsia, a systemic hypertensive disorder of pregnancy, has been associated with the risk of kidney failure, an outcome that may take decades to develop. However, its association with early kidney disease...
Correction to: Kidney Week 2025 Abstract Artificial Intelligence in Autosomal Dominant Polycystic Kidney Disease: Transforming Diagnosis, Risk Stratification, and Therapeutic Interventions SA-PO0555 [0.03%]
对“肾脏周2025摘要：人工智能在常染色体显性多囊肾病中的应用：转化诊断、风险分层和治疗干预”的更正-SA-PO0555
Niloufar Ebrahimi,Wisit Cheungpasitporn,Amir Abdi Pour
Niloufar Ebrahimi