Hongtu Hu,Wei Liang,Guohua Ding
Hongtu Hu
Podocytes, highly specialized glomerular epithelial cells, are essential for maintaining the filtration barrier integrity, yet they are particularly susceptible to metabolic stress. Recent advances have identified metabolic reprogramming as...
Hans-Joachim Anders,Stefanie Steiger,Paola Romagnani
Hans-Joachim Anders
Autoimmune glomerulonephritis (GN) and podocytopathies are immune-mediated kidney diseases with different clinical presentations and histotypes. Traditionally, proteinuria and histotypes are used for prognosis prediction and hence define in...
Authors' Reply: Further Considerations on the Clinical Evaluation of Sotagliflozin in Type 1 Diabetes with CKD [0.03%]
索格列净治疗1型糖尿病患者肾病的临床评价作者回复
Vikas S Sridhar,Ayodele Odutayo,Michael J Davies et al.
Vikas S Sridhar et al.
Further Considerations on the Clinical Evaluation of Sotagliflozin in Type 1 Diabetes with CKD [0.03%]
索格利芬治疗1型糖尿病合并CKD的临床评价进一步考虑
Rui Wang,Jiarun Xie,Ming Wang
Rui Wang
Spatial Transcriptomics Reveals Injured Cells, Signature Genes, and Communication Patterns in the Cyst Microenvironment of Polycystic Kidney Disease [0.03%]
空间转录组学揭示多囊肾病囊肿微环境中受损细胞、标志性基因和通讯模式
Sevtap A Yasinoglu,Claudio Novella-Rausell,Lisanne E Wisse et al.
Sevtap A Yasinoglu et al.
Background: Changes in the cyst microenvironment in Polycystic Kidney Disease (PKD) may drive progressive cyst formation. Bulk- and single-cell RNA sequencing have advanced our understanding of altered signaling; however,...
Holly J Kramer
Holly J Kramer
Computational Characterization of Lymphocyte Topology on Whole Slide Images of Glomerular Diseases [0.03%]
基于全片扫描图像的肾小球疾病淋巴细胞拓扑的计算表征
Xiang Li,Manav Shah,Qian Liu et al.
Xiang Li et al.
Background: The distribution of inflammation in the kidney and its clinical relevance is understudied. This study aims to computationally quantify lymphocyte topology and test its prediction of disease progression. ...
Class 1 Indications for Coronary Revascularization Identified in Prekidney Transplant Screening [0.03%]
冠状动脉血运重建在肾脏移植前筛查中的Ⅰ类适应证识别
Avantika Israni,Bronya L Sandorffy,Celina S Liu et al.
Avantika Israni et al.
Background: Cardiovascular disease is the most common cause of morbidity and mortality in kidney transplant recipients. Screening for coronary disease is frequently required prior to kidney transplantation, but coronary i...
Dillan Prasad,Austin Drysch,Deep Upadhyay et al.
Dillan Prasad et al.
Aldosterone escape refers to the spontaneous and compensatory diuresis that occurs in primary aldosteronism to correct and rebalance fluid homeostasis during conditions of sodium retention. Though widely observed in humans and animals, the ...
Carolin Eul,Britta George
Carolin Eul