Carryn Anderson,Deborah Saunders
Carryn Anderson
Oral mucositis (OM) is a common side effect of radiation therapy for head and neck cancer (HNC). Despite the medical advances in cancer therapy, OM is still virtually inevitable in patients being irradiated for neoplasms of the head and nec...
Kirsten V Nguyen,Cody M Lebeck Lee,Jennifer H Choe
Kirsten V Nguyen
Head and neck cancer is estimated to result in 71,000 new cancer diagnoses and 16,000 deaths in 2024. Of these cases, approximately 14% will be metastatic. Recent changes in treatment paradigms have established immunotherapy as a cornerston...
Reirradiation for Locally Recurrent Head and Neck Cancer: State-of-the-Art and Future Directions [0.03%]
头颈部局部复发肿瘤的再放射治疗：现状及未来方向
Jack Phan,Michael T Spiotto,Christopher D Goodman et al.
Jack Phan et al.
Reirradiation of the head and neck presents one of the most complex and challenging scenarios faced by (for) clinicians due to the narrow therapeutic window. Its use is increasing in clinical practice, often guided by empirical and pragmati...
Predictors of Radiation Resistance and Novel Radiation Sensitizers in Head and Neck Cancers: Advancing Radiotherapy Efficacy [0.03%]
头颈部癌症中放射抵抗的预测因子及新型增敏剂：提升放疗疗效
Aastha Sobti,Heath Skinner,Christopher T Wilke
Aastha Sobti
Radiation resistance in head and neck squamous cell carcinoma (HNSCC), driven by intrinsic and extrinsic factors, poses a significant challenge in radiation oncology. The key contributors are tumor hypoxia, cancer stem cells, cell cycle che...
Immunotherapy With Curative Intent Radiotherapy for Patients With Cancers of the Head and Neck [0.03%]
头颈部癌症患者根治性放疗的免疫治疗
Jordan Hill,Jonathan D Schoenfeld
Jordan Hill
Michael S Chow,Umamaheswar Duvvuri
Michael S Chow
Head and neck squamous cell carcinoma of unknown primary (SSCUP) presents a clinically challenge disease process requiring elaborate multidisciplinary collaboration for effective treatment. With the rise in prevalence HPV associated squamou...
Managing Patients with Head and Neck Cancer and Advanced Age or Comorbidities [0.03%]
如何治疗伴有高龄或合并症的头颈部癌症病人
James M Price,Loren K Mell
James M Price
The dominant treatment paradigm for locoregionally advanced head and neck squamous cell carcinoma (HNSCC) involves postoperative or definitive radiotherapy with concurrent cisplatin chemotherapy. Despite years of research investigating de-i...
Hypofractionated Radiation Therapy in the Definitive Management of Head and Neck Cancer [0.03%]
低分割放射治疗在头颈部癌症确定性治疗中的应用
Dominic H Moon,Musaddiq J Awan
Dominic H Moon
The use of hypofractionated radiation therapy has increased among many cancers, although its use in head and neck cancers remains limited due to concerns regarding acute and late toxicities. Recent retrospective and prospective studies demo...
Personalising Nasopharyngeal Cancer: Systemic Therapy and Radiotherapy Treatment Volumes [0.03%]
鼻咽癌的个体化治疗：全身治疗和放疗靶区体积设定
Benjamin X Z Huang,Xin Zhang,Megan P Kang et al.
Benjamin X Z Huang et al.
Nasopharyngeal carcinoma (NPC) is sensitive to chemotherapy and radiotherapy, with current treatment recommendations largely based on TNM-stage. Radiotherapy remains the backbone of treatment for NPC. Over the past decades, the addition of ...
De-escalation of Adjuvant Therapy in Operatively Managed HPV Associated Oropharyngeal Carcinoma: Current Status and Future Directions [0.03%]
与人乳头瘤病毒相关的经手术治疗的口咽癌的辅助治疗降级：现状及未来方向
Daniel Ma,David M Routman
Daniel Ma
Human papillomavirus (HPV) associated oropharyngeal carcinoma is currently the most frequently diagnosed head and neck cancer in the United States. Due to the generally high cure rates with standard therapies, de-intensification strategies ...