Low-Dose Radiotherapy for Osteoarthritis: Current Evidence, Practical Recommendations and Future Perspectives [0.03%]
低剂量放射治疗骨关节炎：现有证据、实用建议和未来展望
Annika Schlamann,James B Yu,Alexander Rühle
Annika Schlamann
Osteoarthritis (OA) is a widespread degenerative joint disease with increasing prevalence in aging populations. While conservative management such as physiotherapy, NSAIDs, and intraarticular injections form the mainstay of treatment, a sig...
130 Years of Radiotherapy for Nonmalignant Diseases: A Historical Overview [0.03%]
放射治疗非恶性疾病的百年历史回顾(1890-1990)
Oliver Micke,Michael Oertel,Ralph Muecke et al.
Oliver Micke et al.
Radiotherapy has long been associated with the treatment of malignant tumors, yet its application in nonmalignant (benign) diseases predates many contemporary oncologic indications and has played a critical role in shaping the broader field...
Biological Effects of Low-Dose Radiation Therapy: From Mechanistic Aspects to Translational Approaches and Challenges [0.03%]
低剂量辐射治疗的生物学效应：从机制方面到转化方法和挑战
Anna-Jasmina Donaubauer,Lia Mogge,Philipp Schubert et al.
Anna-Jasmina Donaubauer et al.
Low dose radiation therapy (LDRT) is commonly applied for its pain and symptom-relieving effects in the treatment of different benign diseases, such as chronic degenerative and inflammatory, or hyperproliferative disorders. Most clinical tr...
Jean L Nakamura
Jean L Nakamura
Radiotherapy is a valuable treatment option for a variety of nonmalignant diseases. As the indications for low-dose radiotherapy to benign conditions evolve, it is prudent to consider risks and how these might weigh against the benefits of ...
Isabel Falke,Ulrich Schäfer,Oliver Micke et al.
Isabel Falke et al.
Radiotherapy is increasingly used for benign diseases, especially in Germany, where over 50% of radiation treatments address nonmalignant conditions such as osteoarthritis, plantar fasciitis, and Dupuytren's disease. Low-dose regimens have ...
Radiotherapy for Nonmalignant Eye Diseases: Graves' Ophthalmopathy - Pseudotumor Orbitae [0.03%]
非恶性眼病的放射治疗：格雷夫斯眼病-假性眼眶肿瘤
Michael Heinrich Seegenschmiedt,Hans Theodor Eich,Gabriele Reinartz
Michael Heinrich Seegenschmiedt
Orbital radiotherapy (RT) is an effective treatment for moderate-to-severe Graves´ ophthalmopathy (GO), especially when combined with steroids, as it reduces painful eye symptoms associated with retroorbital and eye lid soft tissue swellin...
Functional Radiotherapy for Non-Malignant Diseases: The Potential of Ionizing Radiation Beyond Cancer Treatment [0.03%]
功能性放射治疗在非恶性疾病中的应用：离子辐射在癌症治疗以外的潜力
Alexander Rühle,Thomas F DeLaney
Alexander Rühle
This special issue, "Functional Radiotherapy for Non-Malignant Diseases - The Potential of Ionizing Radiation Beyond Cancer Treatment", addresses one of the oldest yet often overlooked areas of radiation medicine: the therapeutic use of ion...
Maria Farooq,Michael J Pishvaian
Maria Farooq
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies with dismal 5-year survival rates. Characterized by its complex tumor microenvironment and resistance to conventional therapies, PDAC has historically been ...
Madeleine D Hunter,Nupur Shridhar,Kate Mlouk et al.
Madeleine D Hunter et al.
This manuscript describes the evolution in the operative management of pancreatic cancer. Early attempts at pancreatic resection were met with daunting peri‑operative outcomes but were fine-tuned to yield today's established pancreatic res...
Kai-Li Liang,Matthew Z Guo,Neeha Zaidi
Kai-Li Liang
Pancreatic ductal adenocarcinoma (PDAC) is anticipated to be the second leading cause of cancer-related death in the United States by 2030. For the majority of patients who are diagnosed with de novo metastatic disease, 5-year overall survi...