The Heterogeneity of B Cells Potentially Contributes to Metastasis of Clear Cell Renal Cell Carcinomas [0.03%]
异质性B细胞有可能会导致透明细胞肾细胞癌的转移
Yuanhong Chen,Chun Guo,Shaoang Huang et al.
Yuanhong Chen et al.
Background: Clear cell renal cell carcinoma (ccRCC) exhibits extensive immune infiltration, yet the influence of immunological heterogeneity on clinical outcomes remains poorly elucidated. ...
The Association Between Lymphocyte-Monocyte Ratio, Tumor-Infiltrating Lymphocytes, and Tumor-Associated Macrophages with 3-Year Progression-Free Survival in Advanced Local Stage Nasopharyngeal Cancer Patients [0.03%]
淋巴细胞单核细胞比值与局部晚期鼻咽癌患者病程三年无进展生存率的关系研究
Ni Putu Merlynda Pusvita Dewi,Andhika Rachman,Lisnawati Lisnawati et al.
Ni Putu Merlynda Pusvita Dewi et al.
Nasopharyngeal cancer (NPC) is a major health burden in Indonesia, and reliable prognostic biomarkers are needed to guide treatment decisions. This study examined associations between lymphocyte-monocyte ratio (LMR), tumor-infiltrating lymp...
In Vivo Pharmacokinetics, Bio-Distribution and anti-Tumor Activity of Docetaxel-Loaded Folate Targeted Biocompatible Polymeric Micelles [0.03%]
载多西他赛的叶酸靶向生物相容性聚meric micelles的药代动力学、分布及抗肿瘤活性研究
Moloud Kazemi,Jaber Emami,Farshid Hasanzadeh et al.
Moloud Kazemi et al.
Anti-tumor agent, docetaxel (DTX), was incorporated into novel pre-synthesized pH-triggered folate-targeted polymeric micelles to overcome insufficient drug accumulation at the tumor site and to reduce side effects in healthy tissues. Tumor...
Bispecific Antibodies in Multiple Myeloma: A Concise Review of Current Treatments [0.03%]
治疗多发性骨髓瘤的双特异性抗体：当前治疗方法综述
Amir M Ansari,Sogol Attaripour,Sahil Garg et al.
Amir M Ansari et al.
The treatment landscape for multiple myeloma (MM) has evolved significantly over the years; however, the disease remains incurable. Heavily pretreated patients with refractory disease to anti-CD38 therapies, proteasome inhibitors (PIs), and...
Adrenal Carcinoma Laterality is of Limited Clinical Significance: A National Perspective [0.03%]
全国范围内的肾上腺癌的临床意义有限性：单侧与双侧肾上腺癌的对比研究
Mohammad H Hussein,Peter P Issa,Tessa R Lavorgna et al.
Mohammad H Hussein et al.
The clinical implication of adrenal cancer laterality is not well investigated. This retrospective study used the National Cancer Database, including 3962 patients with primary adrenal malignancies. Similar analyses of patients with adrenal...
Roles of Metastasis Associated Fibroblasts in Paclitaxel Resistance of Brain Metastatic Tumor Cells: Evaluation in Metastatic Organoids [0.03%]
转移器官类体中转移相关成纤维细胞在紫杉醇耐药中的作用评估
Mahnaz Siahi,Mohammad Kamalabadi-Farahani,Amir Atashi
Mahnaz Siahi
Background: Some breast cancer patients experience the devastating effects of brain metastases. The metastasis-associated fibroblasts (MAFs), the most abundant cells in the metastatic microenvironment, have an important r...
The Association of NSCLC and Dementia - A Population-Based Cohort Study in Taiwan [0.03%]
台湾NSCLC与痴呆的关联-基于人群的一项队列研究
Yi-Fang Chen,Heng-Jun Lin,Yung-Shuo Kao
Yi-Fang Chen
Introduction: The relationship between cancer and dementia remains complex, and evidence regarding non-central nervous system (CNS) cancers such as non-small cell lung cancer (NSCLC) is inconsistent. This population-based...
The Evolving Role of Surgery in Hepatocellular Carcinoma Management: From Resection to Multidisciplinary Strategy [0.03%]
从切除到多学科策略：外科在肝细胞癌管理中作用的演变
Takehiro Okabayashi,Motoyasu Tabuchi,Teppei Tokumaru et al.
Takehiro Okabayashi et al.
Background: Hepatocellular carcinoma (HCC) frequently develops in the setting of chronic liver disease, making its management uniquely complex and historically centered on surgery. ...
Global, Regional, and National Burden of Ovarian Cancer Attributable to High Body-Mass Index Among Women Aged 55 Years and Older: A GBD 2021 Analysis [0.03%]
2021年全球、区域和国家层面上高体重指数所致≥55岁女性卵巢癌疾病负担：基于GBD 2021的分析
Jingfei Zheng,Hongfeng Li,Xuehe Li et al.
Jingfei Zheng et al.
Background: High body-mass index (BMI) defined in the Global Burden of Disease Study as BMI above the theoretical minimum risk exposure level, is an established modifiable risk factor for ovarian cancer, particularly amon...
Liquid Biopsy Biomarkers as Predictors of TNBC Recurrence: A Systematic Review [0.03%]
循环生物标志物在三阴性乳腺癌复发预测中的作用：系统综述
Nur Rahadiani,Dyah Laksmi Dewi,Mohammad Ghozali
Nur Rahadiani
Introduction: Triple-negative breast cancer (TNBC) is associated with high recurrence and mortality. Liquid biopsy biomarkers, such as circulating tumor DNA (ctDNA), cell-free DNA (cfDNA), and microRNAs (miRNAs), offer no...