Examining the Direct and Indirect Effects of Socioeconomic Status on Colorectal Cancer Using Structural Equation Modeling [0.03%]
利用结构方程模型探讨社会经济地位对大肠癌的直接和间接影响
Jing Zhao,Keming Zhang,Yun Zhu et al.
Jing Zhao et al.
The direct and indirect effects of socioeconomic status (SES) on colorectal cancer (CRC) were examined using structural equation modeling in a case-control study with 488 CRCs and 651 controls. SES was measured by education, income and resi...
Fangran Liu,Paul David Blakeley,Ka Chun Wu et al.
Fangran Liu et al.
Background: Bone morphogenetic protein 2 (BMP2) is essential for bone development and repair in vertebrates. Its role in tumorigenesis and progression remains incompletely characterized. ...
Early Changes in Lymphocyte/Monocyte Ratio on Treatment as a Prognostic Marker to Predict Overall Survival in Patients with Advanced Cancer Treated with Immune Checkpoint Inhibitors [0.03%]
免疫检查点抑制剂治疗晚期癌症患者的早期淋巴细胞/单核细胞比变化作为总生存期预后的预测标记物
Sandip H Patel,Songzhu Zhao,Mingjia Li et al.
Sandip H Patel et al.
Background: A low absolute lymphocyte/monocyte ratio (LMR) in the peripheral blood is associated with poor prognosis in various cancers; however, its role as a predictive biomarker has not been well defined in the era of ...
Investigating the Impact of Peptide-Based Vaccines on Various Types of Cancer: A Systematic Review [0.03%]
基于肽的癌症疫苗对各种类型肿瘤影响的系统评价研究
Arezoo Esmaeili
Arezoo Esmaeili
This review analyzed 12 studies to evaluate the safety, immunogenicity, and therapeutic efficacy of peptide-based cancer vaccines across various tumor types, including breast, gynecological, head and neck, and gastrointestinal cancers. The ...
Selection of Criteria in the Diagnosis Approach of Paraneoplastic Fever in Adults With Solid Neoplasia Using a Delphi Method [0.03%]
Delphi法在成人固體腫瘤並發副肿瘤发热诊断体系中的标准选择
Matthieu Bainaud,Arnaud Saillant,Nicolas Isambert et al.
Matthieu Bainaud et al.
Purpose: Paraneoplastic fever (PF) is an exclusion diagnosis that affects around 10% of patients in oncology, combining fever of unknown origin and the presence of cancer. There is no consensus or guidelines in the litera...
Progress in Development of Lung Cancer Survival Prediction Models Using Machine Learning Based on SEER Database [0.03%]
基于SEER数据库的机器学习肺癌生存预测模型研究进展
Ye Zhang,Jiaye Wang,Shiyu Hu et al.
Ye Zhang et al.
The SEER (Surveillance, Epidemiology, and End Results) database, a comprehensive public repository of clinical oncology data, has been increasingly used to construct clinical prediction models for predicting the prognosis of cancer. With th...
Interplay Between ERK1/2 Signaling Pathway and Estradiol Receptor Modulates ER Targeted Genes Involved in Progression of Estrogen Responsive Breast Cancers [0.03%]
ERK1/2信号途径与雌二醇受体的相互作用调节ER靶基因参与雌激素反应性乳腺癌的发展
Rajeshwari H Patil,Kavya K,Naveen Kumar M et al.
Rajeshwari H Patil et al.
Breast cancer is a leading global health concern, while the endocrine resistance in breast cancer poses a critical challenge, directly undermining the long-term effectiveness of hormone therapies and significantly impacting patient survival...
AURKA Enhances Antitumor Immunity by Activating CD4+ T Cell Proliferation in Colorectal Cancer [0.03%]
AURKA通过激活结直肠癌中CD4⁺T细胞增殖来增强抗肿瘤免疫能力
Yidong Xu,Wei Wang,Jiazi Yu et al.
Yidong Xu et al.
Introduction: Colorectal cancer (CRC) ranks third globally in cancer incidence. Aurora Kinase A (AURKA) critically regulates tumor proliferation and microenvironment, yet its dual CRC roles remain unclear. ...
Self-Supervised Learning Method for Breast Cancer Detection with Image Feature Set and Modified U-Net Segmentation Using Whole Slide Image [0.03%]
基于图像特征集和改进U-Net分割的全滑动病理图像乳腺癌自监督学习方法检测
Sangishetti Karunakar,Praveen Pappula
Sangishetti Karunakar
Breast cancer (BC) is the second most prevalent cause of death for women and the most frequently diagnosed malignancy. Early identification of this deadly illness lowers treatment costs while significantly improving survival rates. In contr...
Recent Advances in Nanocarrier Systems for the Co-Delivery of siRNA and Chemotherapeutic Drug for Breast Cancer Therapy [0.03%]
用于乳腺癌治疗的siRNA和化学药物共递送纳米载体系统的最新进展
Neha Laxane,Khushwant S Yadav
Neha Laxane
Breast cancer's heterogeneity demands innovative therapies. Co-delivery of therapeutics using nanocarriers, especially siRNA combined with other chemotherapeutic drugs, presents a promising avenue. These systems safeguard siRNA, enhance its...