De-escalation of inhaled corticosteroids and other maintenance asthma therapies in dupilumab-treated patients with severe asthma: a real-world study [0.03%]
Dupixent治疗的重度哮喘患者吸入皮质类固醇及其他维持性哮喘疗法降级的真实世界研究
Matteo Bonato,Elisabetta Favero,Michele Ciresi et al.
Matteo Bonato et al.
Background: Biologic therapies for severe T2-high asthma demonstrated oral corticosteroid-sparing effects, but evidence on the harmlessness of de-escalating inhaled corticosteroids and other in patients controlled with du...
Latent profile analysis of breathlessness catastrophizing in patients with chronic obstructive pulmonary disease [0.03%]
慢性阻塞性肺疾病患者的呼吸困难灾难化潜在剖面分析
Xiaolang Miao,Yanxia Han,Xiaoliang Jin et al.
Xiaolang Miao et al.
Objectives: This study aimed to examine the latent profile characteristics of breathlessness catastrophizing (BC) in patients with chronic obstructive pulmonary disease (COPD), and explore the influencing factors across t...
Severity-based evaluation of dynamic airway collapse and tracheobronchomalacia: integrated clinical, functional and bronchoscopic assessment with a diagnostic-therapeutic algorithm in a prospective cohort [0.03%]
基于严重程度的动态气道塌陷和气管/支气管软化的评价:前瞻性队列的临床、功能和支气管镜综合评估及诊断治疗算法
María Sánchez-Samblancat,Elsie Daviana Meneses-Petersen,Andrés Briones-Gómez et al.
María Sánchez-Samblancat et al.
Introduction: Excessive dynamic airway collapse (EDAC) and tracheobronchomalacia are increasingly recognised causes of expiratory airflow limitation, although their clinical relevance remains a matter of ongoing debate, p...
Real-world Efficacy, Safety and Heterogenicity of Efficacy of Elexacaftor-Tezacaftor-Ivacaftor in Younger Children (6-11 Years Old) with Cystic Fibrosis [0.03%]
下一代CF患儿(6-11岁)中Elexacaftor-Tezacaftor-Ivacaftor疗效、安全性和疗效异质性的真实世界研究
Shahid Sheikh,Melissa Holtzlander,Mariah Eisner et al.
Shahid Sheikh et al.
Background: Heterogenicity of efficacy of elexacaftor-tezacaftor-ivacaftor (ETI) therapy in the real world in younger children (6-11 years old) is not known. ...
Validity of transcutaneous capnometry in prolonged use in a patient population with acute respiratory failure [0.03%]
透皮式二氧化碳监测在急性呼吸衰竭患者中长时间使用的有效性研究
Martin Kächele,Magdalena Hasmüller,Alexander Kalner et al.
Martin Kächele et al.
Background: Transcutaneous capnometry is a widespread method for monitoring carbon dioxide in respiratory care. Studies on its use in emergency medicine, the sensors long-term stability its practicability in this setting ...
Impact of obstructive lung disease on survival in patients with rheumatoid arthritis related interstitial lung disease [0.03%]
阻塞性肺疾病对类风湿关节炎相关间质性肺病患者生存率的影响
Lee M Fidler,Omri A Arbiv,Jolene H Fisher et al.
Lee M Fidler et al.
Chronic obstructive pulmonary disease (COPD) and asthma are common comorbidities in rheumatoid arthritis related interstitial lung disease (RA-ILD), yet their impact on health outcomes is poorly understood. Using health services data from O...
Baseline predictors of short- and long-term clinical remission under mepolizumab in severe eosinophilic asthma in real-world practice [0.03%]
真实世界实践中重度嗜酸粒细胞性哮喘患者接受美普兹单抗治疗后短期内和长期临床缓解的基线预测因素
Belén Muñoz Sánchez,Antonio León Lloreda,David Carlos Echavarría Kashmiri et al.
Belén Muñoz Sánchez et al.
Clinical remission has emerged as a relevant treatment target in severe uncontrolled asthma (SUA), although predictors of remission under long-term biologic therapy remain insufficiently characterized. We aimed to identify baseline predicto...
Use of dual targeting during volume control ventilation is associated with increased delivery of non-lung-protective tidal volumes [0.03%]
双重目标设定容量控制通气与非保护性的潮气量相关
Meghana Moodabagil,Robert Easterling,Alex Carter et al.
Meghana Moodabagil et al.
Purpose: Dual targeting (DT) is a patient-comfort ventilator feature that allows for increased flow in response to patient demand. Since flow is augmented above the set flow, larger tidal volumes (VT) than set may be deli...
The correlation between age, chronic hiccup history, and hiccup frequency preceding and following dexamethasone therapy initiation: A correlational study [0.03%]
年龄、慢性打嗝史和地塞米松治疗前后的打嗝频率之间的相关性:一项相关性研究
Bnar Jalal Muhammad,Mustafa AbdulMonam Zainel,Hersh Nafeh Bahaddin et al.
Bnar Jalal Muhammad et al.
Background: Dexamethasone-associated hiccups (DAH) can severely lower patient quality of life. Despite being a recognized adverse effect, comprehensive clinical data on predictive patient-specific risk factors remain scar...
Healthcare Professionals' Awareness and Practice Regarding the Environmental Impact of Inhalers: A Scoping Review [0.03%]
关于吸入剂环境影响的意识和实践:系统综述
Yasir Alhazmi,Philip Chi Lip Kwok,Hoang Anh Tu et al.
Yasir Alhazmi et al.
Background: Inhalers are essential for managing respiratory diseases but pose an environmental impact, especially those containing propellants, which are potent greenhouse gases. Healthcare professionals can reduce the en...