Nicola J Lee,Herbert Herzog
Nicola J Lee
Neuropeptide Y (NPY), a classic neuronal regulator of energy homeostasis, is now also known to be involved in the control of bone homeostasis. Of the five known Y receptors through which the NPY family of ligands signals, the Y1 and Y2 rece...
Stimulatory effect of growth hormone-releasing hormone (GHRH(1-29)NH2) on the proliferation, VEGF and chromogranin A secretion by human neuroendocrine tumor cell line NCI-H727 in vitro [0.03%]
生长激素释放激素(GHRH(1-29)NH2)促神经内分泌肿瘤细胞株NCI-H727增殖、VEGF和嗜铬颗粒A分泌的作用体外研究
Tomasz Stepień,Małgorzata Sacewicz,Hanna Lawnicka et al.
Tomasz Stepień et al.
Growth hormone-releasing hormone (GHRH) and its receptors have been implicated in a variety of cellular processes like cell survival, proliferation, apoptosis, angiogenesis and neoplastic transformation of various non-pituitary tissues. Her...
The anorexigenic peptide cocaine-and-amphetamine-regulated transcript modulates rem-sleep in rats [0.03%]
可卡因和阿米巴素调节多肽通过调节快速眼动睡眠而产生食欲不振的作用机制
M Méndez-Díaz,E Domínguez Martín,M Pérez Morales et al.
M Méndez-Díaz et al.
It is known that the sleep-waking cycle is modulated by several molecules that may also regulate food intake, among them several neuropeptides. The cocaine-and-amphetamine-regulated transcript has been studied in relation to food ingestion,...
Nociceptin/orphanin FQ and NOP receptor gene regulation after acute or repeated social defeat stress [0.03%]
急性或重复性社会挫败应激后的伤害性肽和受体基因表达的调控规律研究
Megan K Green,Darragh P Devine
Megan K Green
Antagonists of the NOP receptor have antidepressant effects in rodent models, suggesting that the N/OFQ-NOP system may play an important role in affective disorders. Furthermore, multiple lines of experimental evidence link N/OFQ neurotrans...
Endogenous peptide: Met-enkephalin-Arg-Phe, differently regulate expression of opioid receptors on chronic treatment [0.03%]
内源性多肽：代谢 - 内啡肽 - 阿瓜 - 芬将在慢性治疗中不同地调节阿片受体的表达
Ishwar Dutt Vats,Snehlata Chaudhary,Jayashree Karar et al.
Ishwar Dutt Vats et al.
Endogenous peptide, Met-enkephalin-Arg-Phe (Tyr-Gly-Gly-Phe-Met-Arg-Phe; MERF) induces effects like antinociception, inhibit contraction of guinea pig ileum, mouse vas deferens and anti-tussive action. However, results regarding its functio...
Signaling pathways in PACAP regulation of VIP gene expression in human neuroblastoma cells [0.03%]
人神经母细胞瘤细胞中PACAP调节VIP基因表达的信号通路
Birgitte Falktoft,Birgitte Georg,Jan Fahrenkrug
Birgitte Falktoft
Ganglia expressing the neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) innervate vasoactive intestinal peptide (VIP) containing neurons suggesting a role of PACAP in regulating VIP expression. Human NB-1 neuroblastom...
Effects of TRH and its analogues on primary cortical neuronal cell damage induced by various excitotoxic, necrotic and apoptotic agents [0.03%]
TRH及其类似物对各种兴奋性、坏死性和凋亡性剂诱导的原发皮层神经元细胞损伤的影响
D Jantas,L Jaworska-Feil,A W Lipkowski et al.
D Jantas et al.
The tripeptide thyrotropin-releasing hormone (TRH, pGlu-His-Pro-NH2) has been shown to possess neuroprotective activity in in vitro and in vivo models. Since its potential utility is limited by relatively rapid metabolism, metabolically sta...
Xue Zhou,Jin-Wei Yang,Wei Zhang et al.
Xue Zhou et al.
Neuroplasticity occurs in the spinal cord in response to lesions, but less is known about the underlying mechanism. This investigation explored the role of intrinsic NGF in axonal sprouting of dorsal root ganglia (DRG) in cats subjected to ...
K M Hegadoren,T O&#x;Donnell,R Lanius et al.
K M Hegadoren et al.
A role for beta-endorphin (beta-END) in the pathophysiology of major depressive disorder (MDD) is suggested by both animal research and studies examining clinical populations. The major etiological theories of depression include brain regio...
Brain derived neurotrophic factor and neurotrophin-4 employ different intracellular pathways to modulate norepinephrine uptake and release in rat hypothalamus [0.03%]
脑源性神经营养因子和神经生长因子以不同的细胞内信号转导途径调节大鼠下丘脑去甲肾上腺素的摄取和释放
M Rodríguez Fermepin,M Trinchero,J Minetto et al.
M Rodríguez Fermepin et al.
Classical actions of the neurotrophin family are related to cellular survival and differentiation. Moreover, acute effects of neurotrophins have been reported. Although neurotrophins effects on synaptic transmission at central nervous syste...