Yevgenia Shneider,Yael Shtrauss,Gal Yadid et al.
Yevgenia Shneider et al.
Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) is a multi-functional neuropeptide that acts through activation of three common G-protein coupled receptors (VPAC1, VPAC2 and PAC1). In this study, we have investigated the gene exp...
Protective effects of TRH and its analogues against various cytotoxic agents in retinoic acid (RA)-differentiated human neuroblastoma SH-SY5Y cells [0.03%]
TRH及其类似物对视黄酸诱导的人神经母细胞瘤SH-SY5Y细胞的细胞保护作用
L Jaworska-Feil,D Jantas,M Leskiewicz et al.
L Jaworska-Feil et al.
TRH (thyroliberin) and its analogues were reported to possess neuroprotective effects in cellular and animal experimental models of acute and chronic neurodegenerative diseases. In the present study we evaluated effects of TRH and its three...
Role of substance P (SP) and calcitonin gene-related peptide (CGRP) in gibbon-ape-leukemia virus (GALV) transduction of CD34+ cells [0.03%]
Substance P和降钙素基因相关肽在地猴 leukemia virus转导CD34+细胞中的作用
Somayeh Shahrokhi,Kamran Alimoghaddam,Ardeshir Ghavamzadeh
Somayeh Shahrokhi
Aims: Optimization of transduction condition is an important goal to improve gene transduction. Therefore, we aimed to assess the effect of SP and/or CGRP as novel growth/transducing factors on the efficacy of CD34(+) tra...
Aysegül Ilhan,Sazan Rasul,Alexander Dimitrov et al.
Aysegül Ilhan et al.
Neuropeptide Y (NPY) is an important hormone in appetite regulation. Although the contribution of NPY to metabolic disease has been previously demonstrated, there are only a few reports addressing NPY plasma levels under distinct diabetic c...
Mass spectrometric analysis of activity-dependent changes of neuropeptide profile in the snail, Helix pomatia [0.03%]
利用质谱分析法分析活体蜗牛神经肽的活性及依赖性变化
Z Pirger,A Lubics,D Reglodi et al.
Z Pirger et al.
Terrestrial snails are able to transform themselves into inactivity ceasing their behavioral activity under unfavorable environmental conditions. In the present study, we report on the activity-dependent changes of the peptide and/or polype...
The role of anorexigenic and orexigenic neuropeptides and peripheral signals on quartiles of weight loss in obese adolescents [0.03%]
食欲抑制性及食欲促进性神经肽和外周信号在肥胖青少年体重减轻四分位数中的作用
Lila Missae Oyama,Claudia Maria Oller do Nascimento,June Carnier et al.
Lila Missae Oyama et al.
Obesity is characterized as an inflammatory state associated with a modification in the pattern of adipokine secretion. The present study aimed to assess the role of anorexigenic and orexigenic neuropeptides and peripheral signals in obese ...
The vasoactive intestinal peptide-receptor system is involved in human glioblastoma cell migration [0.03%]
血管活性肠肽受体系统参与人类胶质母细胞瘤细胞迁移
Stéphanie Cochaud,Lucie Chevrier,Annie-Claire Meunier et al.
Stéphanie Cochaud et al.
Glioblastoma multiforme (GBM) is the most aggressive form of brain tumor in adults. This cancer has an infiltrative nature and the median survival of patients is about one year. Vasoactive intestinal peptide (VIP) belongs to a structurally ...
Distinct distribution of corticotropin releasing factor receptors in human breast cancer [0.03%]
人乳腺癌中促肾上腺皮质激素释放因子受体的分布不同
A Kaprara,K Pazaitou-Panayiotou,M C Chemonidou et al.
A Kaprara et al.
The hypothalamic neuropeptide corticotropin releasing factor (CRF) has been found in several types of human cancer, where its biological role is not clarified. In experimental models of breast cancer CRF has been shown to exert anti-prolife...
Vasoactive intestinal peptide induces vascular endothelial growth factor production in human HaCaT keratinocytes via MAPK pathway [0.03%]
活性肠肽通过MAPK途径诱导人HaCaT角质细胞产生血管内皮生长因子
Xiao-Jing Yu,Xiao-Hong Ren,Yong-Hao Xu et al.
Xiao-Jing Yu et al.
Psoriasis is a chronic skin disease characterized by abnormal keratinocyte proliferation and differentiation, inflammation, and angiogenesis. Although dysfunction of the immune system is known to be an important factor in the pathogenesis o...
Impaired nocifensive behaviours and mechanical hyperalgesia, but enhanced thermal allodynia in pituitary adenylate cyclase-activating polypeptide deficient mice [0.03%]
胰腺环化酶激活多肽缺陷型小鼠痛行为的改变
K Sándor,V Kormos,B Botz et al.
K Sándor et al.
Pituitary adenylate cyclase-activating polypeptide-38 (PACAP-38) and its receptors (PAC1 and VPAC) have been shown in the spinal dorsal horn, dorsal root ganglia and sensory nerve terminals. Data concerning the role of PACAP in central pain...