Leptin facilitates lordosis behavior through GnRH-1 and progestin receptors in estrogen-primed rats [0.03%]
瘦素通过GnRH-1和孕激素受体促进雌激素诱导大鼠的交配接受行为
Marcos García-Juárez,Carlos Beyer,Alfonso Soto-Sánchez et al.
Marcos García-Juárez et al.
Dose response curves for leptin facilitation of estrous behavior (lordosis and proceptivity) were made by infusing the peptide into the lateral ventricle (icv) of ovariectomized (ovx), ad libitum-fed rats injected 40h previously with 5μg o...
Neuropeptide Y acts within the rat testis to inhibit testosterone secretion [0.03%]
神经肽Y通过抑制大鼠睾丸内睾酮分泌而减少性欲
Camryn D Allen,Beatrice Waser,Meike Körner et al.
Camryn D Allen et al.
The factors that influence Leydig cell activity currently include peptides such as neuropeptide Y (NPY). In this work we investigated the ability of this compound, injected directly into the testes of adult male rats, to alter testosterone ...
Altered host response to murine gammaherpesvirus 68 infection in mice lacking the tachykinin 1 gene and the receptor for substance P [0.03%]
缺少tachykinin 1基因和物质P受体的小鼠中柯萨奇病毒腺病毒肠病毒68型感染的宿主反应发生变化
John P Quinn,Anja Kipar,David J Hughes et al.
John P Quinn et al.
The tachykinins are implicated in neurogenic inflammation and the neuropeptide substance P in particular has been shown to be a proinflammatory mediator. A role for the tachykinins in host response to viral infection has been previously dem...
Roland Lang,Barbara Kofler
Roland Lang
The immune system defends the organism against invading pathogens. In recent decades it became evident that elimination of such pathogens, termination of inflammation, and restoration of host homeostasis all depend on bidirectional crosstal...
Gonadotropin-releasing hormone reduces the severity of experimental autoimmune encephalomyelitis, a model of multiple sclerosis [0.03%]
促性腺激素释放激素可降低实验性自身免疫性脑脊髓炎的严重程度，而实验性自身免疫性脑脊髓炎是多发性硬化病的一种模型
J Luis Quintanar,Eva Salinas,Andrés Quintanar-Stephano
J Luis Quintanar
It has been reported that the spinal cord possesses Gonadotropin-releasing hormone (GnRH) receptor and that GnRH has neurotrophic properties. Experimental autoimmune encephalomyelitis (EAE) causes neurodegeneration in spinal cord. Thus, the...
A neurotensin analog, NT69L, attenuates intravenous nicotine self-administration in rats [0.03%]
神经紧张素类似物NT69L可减轻大鼠静脉注射尼古丁的自我给药行为
Mona Boules,Alfredo Oliveros,Yanqi Liang et al.
Mona Boules et al.
NT69L is a neurotensin analog that blocks nicotine-induced locomotor activity and has sustained efficacy in a rat model of nicotine-induced sensitization when administered peripherally. Additionally, NT69L attenuates food-reinforcement in r...
Unique biological function of cathepsin L in secretory vesicles for biosynthesis of neuropeptides [0.03%]
分泌颗粒中猫粮L的独特生物学功能用于神经肽的生物合成
Lydiane Funkelstein,Margery Beinfeld,Ardalan Minokadeh et al.
Lydiane Funkelstein et al.
Neuropeptides are essential for cell-cell communication in the nervous and neuroendocrine systems. Production of active neuropeptides requires proteolytic processing of proneuropeptide precursors in secretory vesicles that produce, store, a...
Effect of alpha-melanocyte stimulating hormone on locomotor recovery following spinal cord injury in mice: Role of serotonergic system [0.03%]
α-黑素细胞刺激激素对脊髓损伤小鼠运动功能恢复的影响及其血清素能系统介导作用的研究
Ashish P Bharne,Manoj A Upadhya,Dadasaheb M Kokare et al.
Ashish P Bharne et al.
The present study underscores the effect of serotonergic antagonist on alpha-melanocyte stimulating hormone (α-MSH) induced neuronal regeneration. Swiss-albino mice were subjected to experimental spinal cord injury (ESCI) and treated with ...
Cardiac ischemia-reperfusion regulates sympathetic neuropeptide expression through gp130-dependent and independent mechanisms [0.03%]
心脏缺血-再灌注通过依赖和不依赖gp130的机制调节交感神经肽表达
Eric N Alston,Diana C Parrish,Wohaib Hasan et al.
Eric N Alston et al.
Cardiac function is regulated by a balance of sympathetic and parasympathetic transmission. Neuropeptide Y (NPY) and galanin (GAL) released from cardiac sympathetic neurons inhibits parasympathetic transmission in the heart. Sympathetic pep...
Effects of intracerebroventricular galanin or a galanin receptor 2/3 agonist on the lesion induced by transient occlusion of the middle cerebral artery in female rats [0.03%]
内侧脑室注射galanin或galanin受体2/3激动剂对雌性SD大鼠短暂性大脑中动脉闭塞后损伤的影响
Lovisa Holm,Elvar Theodorsson,Tomas Hökfelt et al.
Lovisa Holm et al.
Several studies have shown that injury to the central and peripheral nervous system can increase expression of galanin, a 29 amino acid neuropeptide. Moreover, there is evidence that galanin, especially through its galanin receptor 2 (GalR2...