Effects of oxytocin on behavior and neurotrophic factors in the brain of aged female rats exposed to chronic social isolation [0.03%]
催产素对慢性社会隔离老年雌鼠行为及脑内神经营养因子的影响
Helin Demirtas,Burcu Acikgoz,Ayca Arslankiran et al.
Helin Demirtas et al.
This study aimed to investigate the effects of social isolation stress and intranasally administered oxytocin on physiological and behavioral alterations during aging in rats. A total of 28, aged female Sprague-Dawley rats were allocated in...
Luteolin ameliorates kainic acid-induced seizure by modulating GADD45B and reducing oxidative stress in hippocampal neurons [0.03%]
黄酮类化合物luteolin通过调节GADD45B和减少氧化应激改善海马神经元中kainic酸诱导的癫痫发作
Can Luo,Zhi Wang,Junbao Liao et al.
Can Luo et al.
Epilepsy is a prevalent neurological disorder impacting numerous people. However, existing anti-seizure medications frequently fall short of adequately managing seizures, highlighting the urgent need for the development of novel therapeutic...
Regulation of the gut-brain-pituitary-gonad axis in tilapia: Evidence for the involvement of orexin [0.03%]
罗非鱼肠-脑-垂体-性腺轴的调节：下丘脑催产素能系统参与的证据
Mallikarjun Gouda,C B Ganesh
Mallikarjun Gouda
The neuropeptide orexin is known as the regulator of appetite and is implicated in many physiological functions in vertebrates. Nevertheless, the physiological importance of this peptide within the gut-brain-reproductive axis remains poorly...
Netrin-3 enhances recovery and reduces inflammation following spinal cord injury via suppressing NLRP1 inflammasome activation [0.03%]
Netrin-3通过抑制NLRP1炎性小体激活增强脊髓损伤后的恢复和减少炎症
Zhe Li,Xinghua Song,Jialai Song
Zhe Li
Spinal cord injury (SCI) represents a significant challenge in the field of neurology due to its complex pathology and the limited efficacy of current treatments. The search for effective therapeutic strategies has led to investigations int...
Interaction of glucocorticoids and interleukins in the control of hypothalamic neurohypophysial system output in salt loaded male rats [0.03%]
糖皮质激素和细胞因子在盐负荷雄性大鼠下丘脑神经垂体系统输出控制中的相互作用
R R Ventura,S G Ruginsk,A Lopes da Silva et al.
R R Ventura et al.
The present study investigated the effects of a 4-day salt load (0.3 M NaCl, SL) and dexamethasone treatment (DEXA, 1 mg/Kg, subcutaneous) on the mechanisms possibly underlying glucocorticoid-mediated effects on hypothalamic neurohypophysea...
PQK7: A novel peptide inhibitor targeting alpha-synuclein fibrillogenesis in Parkinson's disease [0.03%]
帕金森病中新靶向α-突触核蛋白纤维化的肽类抑制剂PQK7
Maryam Motamedi,Dina Morshedi,Najaf Allahyari Fard
Maryam Motamedi
The accumulation of alpha-synuclein (⍺-Syn) fibrils plays a central role in the progression of Parkinson's disease (PD) and related neurodegenerative disorders. In this context, the development of peptide inhibitors designed to inhibit ⍺-...
Catestatin-like immunoreactivity in the skin and related sensory ganglia [0.03%]
皮肤和相关感觉神经节中类似catestatin的免疫反应性
Victoria Stöckl,Georgios Blatsios,Christian Humpel et al.
Victoria Stöckl et al.
Aim: The chromogranin A-derived peptide catestatin has previously been shown to be a constituent of the sensory innervation of the eye and dental pulp. The antibody used in these studies not only recognizes authentic cate...
Astrocyte Glucose-6-phosphorylase-Beta regulates ventromedial hypothalamic nucleus glucose counterregulatory neurotransmission and systemic hormone profiles [0.03%]
星形胶质细胞葡萄糖-6-磷酸酶-β调节腹内侧下丘脑核葡萄糖的神经传递和全身激素谱
Karen P Briski,Sushma Katakam,Subash Sapkota et al.
Karen P Briski et al.
Brain astrocytes generate free glucose at the conclusion of glycogenolysis or gluconeogenesis by glucose-6-phosphatase-beta (Glc-6-Pase-β) hydrolytic action. Astrocytes shape ventromedial hypothalamic nucleus (VMN) control of glucose count...
Profile of cocaine and amphetamine regulated transcript peptide (CARTp) and Corticotropin-releasing factor (CRF) in the brain of Euphlyctis cyanophlyctis during puddle desiccation [0.03%]
池塘干涸期间印度饰纹蟾(Euphlyctis cyanophlyctis)脑中可卡因和安非他明调控转录肽(CARTp)及促肾上腺皮质激素释放因子(CRF)的状况PROFILE OF COCADNetMessage格式为：中文标题
Swapnil A Shewale,Sunil J Koli,Sneha Sagarkar et al.
Swapnil A Shewale et al.
During the post breeding season, anuran tadpoles are subjected to a wide range of environmental variables due to intermittent dry spells leading to pond desiccation. To avoid these harsh conditions, anurans accelerate rate of metamorphosis....
Factors affecting the physical stability of peptide self-assembly in neurodegenerative disorders [0.03%]
影响神经退行性疾病中肽自组装物理稳定性的因素
Jahnu Saikia,Mouli Sarkar,Vibin Ramakrishnan
Jahnu Saikia
Biological systems comprise of diverse biomolecules, including proteins, nucleic acids, lipids, and carbohydrates. Peptides, which are short chains of amino acids, exhibit unique properties when assembled to nano-level architectures. Self-a...