Protective effect of Prolactin releasing peptide against 1,2-diacetylbenzene -induced neuroinflammation [0.03%]
prolactin释放肽对抗1,2-二乙酰基苯诱发的神经炎症的保护作用
Ngoc Minh Hong Hoang,Wonhee Jo,Min-Sun Kim
Ngoc Minh Hong Hoang
Prolactin-releasing peptide (PrRP) has been investigated as a potential therapeutic for diabetes by the effect of food intake reduction, increasing leptin signaling, and insulin tolerance. Recent studies focused on its synaptogenesis and pr...
Metformin promotes Schwann cell remyelination, preserves neural tissue and improves functional recovery after spinal cord injury [0.03%]
二甲双胍促进施万细胞脱髓鞘后的再髓鞘化以及脊髓损伤后的神经组织修复和功能恢复
Zucheng Huang,Junyu Lin,Hui Jiang et al.
Zucheng Huang et al.
Patients with a spinal cord injury (SCI) usually suffer lifelong disability as a result. Considering this, SCI treatment and pathology study are urgently needed. Metformin, a widely used hypoglycemic drug, has been indicated for its importa...
Changes in working memory induced by lipopolysaccharide administration in mice are associated with metabotropic glutamate receptors 5 and contrast with changes induced by cyclooxygenase-2: Involvement of postsynaptic density protein 95 and down syndrome cell adhesion molecule [0.03%]
脂多糖通过代谢型谷氨酸受体5诱导小鼠工作记忆改变而环氧化酶-2则不然：-postsynaptic density蛋白95和Down综合征细胞粘附分子的参与作用
Katarzyna Stachowicz,Patrycja Pańczyszyn-Trzewik,Magdalena Sowa-Kućma et al.
Katarzyna Stachowicz et al.
The strength and quality of the signal propagated by the glutamate synapse (Glu) depend, among other things, on the structure of the postsynaptic part and the quality of adhesion between the interacting components of the synapse. Postsynapt...
Intrathecal administration of botulinum toxin type a antagonizes neuropathic pain by countering increased vesicular nucleotide transporter expression in the spinal cord of chronic constriction injury of the sciatic nerve rats [0.03%]
肉毒杆菌毒素A脊髓给药通过逆转慢性坐骨神经压迫损伤大鼠脊髓囊泡核苷酸转运体高表达来对抗神经病理性疼痛
Yongqiang Shi,Chaoyang Gong,Wei Nan et al.
Yongqiang Shi et al.
Botulinum toxin type A (BoNT/A) induces direct analgesic effects in neuropathic pain by inhibiting the release of substance P, calcitonin gene-related peptide (CGRP) and glutamate. Vesicular nucleotide transporter (VNUT) was responsible for...
Naloxone could limit morphine hypersensitivity: Considering the molecular mechanisms [0.03%]
纳洛酮可能限制吗啡过敏：考虑分子机制
Mojgan Baratzadeh,Samira Danialy,Shima Abtin et al.
Mojgan Baratzadeh et al.
Background: Naloxone has been used as an opioid antagonist to prevent multiple adverse side effects of opioid-like tolerance and hyperalgesia. This study has investigated naloxone combined with morphine to limit pain hype...
Arginine vasopressin effects on membrane potentials of preoptic area temperature-sensitive and -insensitive neurons in rat hypothalamic tissue slices [0.03%]
精氨酸血管加压素对大鼠下丘脑切片中视前区温度敏感和非敏感神经元膜电位的影响
Yu Tang,Siyuan Liu,Lingzhi Xu et al.
Yu Tang et al.
Arginine vasopressin (AVP) plays a hypothermic regulatory role in thermoregulation and is an important endogenous mediator in this mechanism. In the preoptic area (POA), AVP increases the spontaneous firing and thermosensitivity of warm-sen...
Several neuropeptides involved in parkinsonian neuroprotection modulate the firing properties of nigral dopaminergic neurons [0.03%]
几种与帕金森病神经保护作用相关的神经肽可调节黑质多巴胺能神经元的放电性质
Lei Chen,Cui Liu,Yan Xue et al.
Lei Chen et al.
Parkinson's disease is characterized by progressive degeneration of dopaminergic neurons in the substantia nigra pars compacta. The surviving nigral dopaminergic neurons display altered spontaneous firing activity in Parkinson's disease. Th...
Orexin receptor antagonists in the pathophysiology and treatment of sleep disorders and epilepsy [0.03%]
orexin受体拮抗剂在睡眠障碍和癫痫的发病机制和治疗中的作用
Mohammad Sheibani,Maryam Shayan,Mina Khalilzadeh et al.
Mohammad Sheibani et al.
The correlation between sleep and epilepsy has been argued over the past decades among scientists. Although the similarities and contrasts between sleep and epilepsy had been considered, their intertwined nature was not revealed until the n...
PACAP inhibition alleviates neuropathic pain by modulating Nav1.7 through the MAPK/ERK signaling pathway in a rat model of chronic constriction injury [0.03%]
通过MAPK / ERK信号转导途径调节Nav1.7介导疼痛缓解PCPA抑制剂通过大鼠慢性约束损伤模型治疗神经病理性疼痛
Mingzheng Liu,Fan He,Mengci Shao et al.
Mingzheng Liu et al.
Background: Trigeminal neuralgia is a common chronic maxillofacial neuropathic pain disorder, and voltage-gated sodium channels (VSGCs) are likely involved in its pathology. Prior studies report that pituitary adenylate c...
The role of sensory and sympathetic nerves in craniofacial bone regeneration [0.03%]
感觉和 sympathetich神经在颅面骨再生中的作用
Freshet Assefa
Freshet Assefa
Multiple factors regulate the regeneration of craniofacial bone defects. The nervous system is recognized as one of the critical regulators of bone mass, thereby suggesting a role for neuronal pathways in bone regeneration. However, in the ...