Norepinephrine regulates arginine vasopressin secretion in hypothalamic paraventricular nucleus relating with pain modulation [0.03%]
肾上腺素通过下视丘室旁核调节精氨酸加压素的分泌参与痛觉调制作用
Jun Yang,Hui-Feng Yuan,Wen-Yan Liu et al.
Jun Yang et al.
Our previous study has pointed that arginine vasopressin (AVP) and norepinephrine (NA) are two most important bioactive substances that play a role in hypothalamic paraventricular nucleus (PVN) regulating pain process. The communication was...
Hypothalamic orexin, OX1, alphaMSH, NPY and MCRs expression in dopaminergic D2R knockout mice [0.03%]
多巴胺D2受体基因敲除鼠下丘脑食欲素、MC4-R、NPY和黑皮质素原肽α-MSH表达变化研究
I García-Tornadú,G Díaz-Torga,G S Risso et al.
I García-Tornadú et al.
In 5-month-old male and female dopamine receptor 2 (D2R) knockout mice food intake per animal was unaltered while food per g BW was increased. We wished to evaluate the effect of D2R disruption on different components of energy balance and ...
Involvement of neuropeptide Y in the acute, chronic and withdrawal responses of morphine in nociception in neuropathic rats: behavioral and neuroanatomical correlates [0.03%]
神经肽Y与吗啡在周围神经病理性疼痛大鼠急性、慢性及戒断期镇痛作用的机制研究：行为学和神经解剖学相关性
Manoj A Upadhya,Manoj P Dandekar,Dadasaheb M Kokare et al.
Manoj A Upadhya et al.
Although morphine is a potent antinociceptive agent, its chronic use developed tolerance in neuropathic pain (NP). Furthermore, opioid antagonist naloxone attenuated the antinociceptive effect of neuropeptide Y (NPY). The present study inve...
The role of nitric oxide in the inhibitory effect of ghrelin against penicillin-induced epileptiform activity in rat [0.03%]
胃泌素通过硝基化合物介导抑制大鼠青霉素诱导的癫痫样放电的作用及机制研究
Ali Aslan,Mehmet Yildirim,Mustafa Ayyildiz et al.
Ali Aslan et al.
Ghrelin, a gastric peptide with key action on food intake, has been recently recognized as a potential antiepileptic agent. In the present study, we investigated the involvement of nitric oxide in the effect of ghrelin on penicillin-induced...
Peter Kovacs,Andras Hajnal
Peter Kovacs
Brain insulin has widespread metabolic, neurotrophic, and neuromodulatory functions and is involved in the central regulation of food intake and body weight, learning and memory, neuronal development, neuronal apoptosis, and aging. To under...
Refeeding after prolonged food restriction differentially affects hypothalamic and adipose tissue leptin gene expression [0.03%]
长时间的饮食限制后重新进食对下丘脑和脂肪组织中leptin基因表达的影响不同
Elzbieta Sucajtys-Szulc,Elzbieta Goyke,Justyna Korczynska et al.
Elzbieta Sucajtys-Szulc et al.
Rat adipose tissue is the principal site of leptin synthesis, however, leptin gene expression has been demonstrated in many rat tissues. Some data indicate that leptin produced by human brain and adipose tissue could cooperate in the regula...
The human neurokinin B gene, TAC3, and its promoter are regulated by Neuron Restrictive Silencing Factor (NRSF) transcription factor family [0.03%]
人神经激肽B基因TAC3及其启动子受Neuron Restrictive Silencing Factor(NRSF)转录因子家族调控
S Gillies,K Haddley,S Vasiliou et al.
S Gillies et al.
We have previously shown that one of the major determinants directing the expression of the preprotachykinin-A (TAC1) gene, which encodes the neuropeptide substance P, is the transcription factor Neuronal Restrictive Silencer Factor (NSRF),...
RANTES release contributes to the protective action of PACAP38 against sodium nitroprusside in cortical neurons [0.03%]
PACAP38的神经保护作用与其诱导Cortical神经元释放RANTES有关
Alma Sanchez,Debjani Tripathy,Paula Grammas
Alma Sanchez
Pituitary adenylate cyclase activating polypeptide (PACAP), a promising neuroprotective peptide, plays an important role during development of the nervous system and in regeneration after injury. PACAP directly promotes survival via multipl...
Rapid change of neuropeptide Y levels and gene-expression in the brain of ovariectomized mice after administration of 17beta-estradiol [0.03%]
17β雌二醇对卵巢切除小鼠脑内神经肽Y水平及基因表达的快速改变的影响
Susanne Hilke,Lovisa Holm,Katarina Man et al.
Susanne Hilke et al.
Estrogen alters excitability and changes synaptic morphology in the rat hippocampal formation. We have compared, by means of radioimmunoassay and in situ hybridization, the effects of short-term treatment with 17beta-estradiol on neuropepti...
Johan Runesson,Indrek Saar,Linda Lundström et al.
Johan Runesson et al.
The galanin peptide family and its three receptors have with compelling evidence been implicated in several high-order physiological disorders. The co-localization with other neuromodulators and the distinct up-regulation during and after p...