The international occurrence of ptxP3 genotype macrolide-resistant Bordetella pertussis: A call for updating of clinical practice guidelines [0.03%]
百日咳杆菌耐大环内酯类ptxP3基因型国际流行情况：临床实践指南更新的呼吁
Xinyu Wang,Siyu Chen,Wei Gao et al.
Xinyu Wang et al.
Hypervirulent Klebsiella pneumoniae defined by a five-gene panel predicts mortality in community-acquired bacteremia [0.03%]
五个基因标记定义的高毒力肺炎克雷伯菌预测社区获得性菌血症患者的病死率
Feng-Yee Chang,L Kristopher Siu,Jung-Chung Lin et al.
Feng-Yee Chang et al.
Objectives: Experimental models suggest that the combined presence of iucA, iroB, peg-344, rmpA, and rmpA2 reliably distinguishes hypervirulent Klebsiella pneumoniae (hvKp) from classical strains (cKp). We evaluated the c...
Residual HIV viremia strongly increases cardiovascular disease incidence independent of classical risk factors [0.03%]
残存的人类免疫缺陷病毒血症会显著增加心血管疾病的发生率，且不依赖于经典的风险因素
Twan Otten,Suzanne D E Ruijten,Marc J T Blaauw et al.
Twan Otten et al.
Background: People with HIV (PWH) using antiretroviral therapy are at increased risk to develop cardiovascular diseases (CVD). We hypothesized that residual viremia (RV; unquantifiable low, but detectable viral load) incr...
Beyond genomic inference: Reassessing the origins of post-pandemic macrolide-resistant Bordetella pertussis [0.03%]
基因组推理之外：重新审视大流行后百日咳杆菌宏环肽耐药性的起源
Siyu Chen,Xinyu Wang,Leran He et al.
Siyu Chen et al.
Measles resurgence in the United Kingdom amid waning coverage and widening inequities [0.03%]
英国 measles 疫情卷土重来，疫苗接种率下降和不公平现象加剧
Akaninyene Otu,Bassey Ebenso,James Rudge et al.
Akaninyene Otu et al.
Selective elimination of myeloid HIV reservoirs by targeting pro-survival pathways [0.03%]
通过靶向促生存途径选择性消除髓样HIV库
Min Li,Baichao Sun,Laurie J Minze et al.
Min Li et al.
Objectives: HIV reservoirs in myeloid cells, including tissue-resident macrophages, persist despite antiretroviral therapy, hindering viral eradication. We have tested an approach for HIV clearance through selective elimi...
Persistent T cell phenotypic alterations and early innate immune dysregulation as potential biomarkers of Long COVID [0.03%]
持久的T细胞表型改变和早期先天免疫失调作为长期新冠的潜在生物标志物
Marina Perez Mazzali,Francisco Pérez-Cózar,Paloma Cal-Sabater et al.
Marina Perez Mazzali et al.
Long COVID is a complex condition characterized by a broad spectrum of persistent, multisystemic symptoms that often impair daily activities and cause disability with significant socioeconomic impact. Although several hypotheses have been p...
Trends and patterns of human papillomavirus infection among 33.7 million women in mainland China from 2015 to 2025: A nationwide observational study [0.03%]
2015年至2025年中国大陆3370万女性人乳头瘤病毒感染流行趋势及模式的全国观察性研究
Xi Li,Yamin Sun,Xinchang Lun et al.
Xi Li et al.
Objectives: To explore the trends and patterns of human papillomavirus (HPV) infection in mainland China from 2015 to 2025, and to investigate the distribution of non-infected populations. ...
An emerging tick-borne spotted fever group Rickettsia in China: Isolation, genomics, and human infection of Rickettsia koreansis [0.03%]
中国新现蜱传斑点热群立克次体的分离、基因组学和人感染：Rickettsia koreansis的鉴定
Ming-Zhu Zhang,Zhi-Jie Wang,Hui-Jun Yu et al.
Ming-Zhu Zhang et al.
Objectives: This study aimed to isolate and systematically characterize the emerging Rickettsia koreansis from ticks in China, define its genomic features, and assess its clinical and epidemiological significance for huma...
Urinary rezafungin exposure: First human reports of quantification and early pharmacokinetic insights [0.03%]
尿液中rezafungin的暴露量：人类定量检测和早期药代动力学见解的首项报告
Antoine Hamon,Léo Froelicher Bournaud,Sihem Benaboud et al.
Antoine Hamon et al.