Faecal microbiota transplant to ERadicate gastrointestinal carriage of Antibiotic-Resistant Organisms (FERARO): a feasibility randomised controlled trial [0.03%]
粪菌移植消除抗生素耐药菌的可行性随机对照试验(FERARO)
Blair Merrick,Désirée Prossomariti,Elizabeth Allen et al.
Blair Merrick et al.
Objectives: The gastrointestinal tract (GIT) is a reservoir of multidrug-resistant organisms (MDRO). Colonisation with MDRO precedes invasive infections which can be challenging to treat with excess morbidity and mortalit...
Novel Coronaviruses Identified in Livestock: The Urgent Need to Enhance Coronavirus Surveillance to Mitigate Zoonotic Risks [0.03%]
畜禽中鉴定出新型冠状病毒：为降低人畜共患病风险须加强冠状病毒监测的紧迫性
Kaili Qi,Jie Chen,Xing Ma et al.
Kaili Qi et al.
Long term outcomes in drug resistant tuberculosis with Bedaquiline, Pretomanid and varying doses of Linezolid [0.03%]
不同剂量利奈唑胺贝达喹啉和普雷托南治疗耐药结核病的长期结局研究
Bella Devaleenal Daniel,Sivakumar Shanmugam,Rashi Mehta et al.
Bella Devaleenal Daniel et al.
Objectives: Assess the effectiveness of bedaquiline, pretomanid and linezolid (BPaL) regimens with varying doses and duration of linezolid at the end of 48 weeks post treatment among drug resistant tuberculosis (DR TB) pa...
High dose, subcutaneous injections of benzathine penicillin G (SCIP) to prevent rheumatic fever: a single arm, phase IIa trial of safety and pharmacokinetics [0.03%]
高剂量长效青霉素皮下注射预防风湿热：一项单组、IIa 期安全性和药代动力学试验
Julie Bennett,Sam Salman,Dhevindri Moodley et al.
Julie Bennett et al.
Objectives: This Phase-IIa trial evaluates the safety and pharmacokinetics of high-dose, 10 weekly subcutaneous injections of penicillin (SCIP) in young people with a history of acute rheumatic fever (ARF). ...
Localised increase in necrotising fasciitis associated with a shift to monomicrobial aetiology, South Yorkshire, England, 2023 [0.03%]
英格兰南约克郡2023年坏死性筋膜炎局部增加与单微生物病原体相关的转变
Dominic Ronan,Hannah Holt,Lara Utsi et al.
Dominic Ronan et al.
Objectives: An increase in necrotising fasciitis (NF) was observed in South Yorkshire by plastic surgeons. A public health response was established. Metho...
Metagenomic profiling of hospital wastewater: A comprehensive national scale analysis of antimicrobial resistance genes and opportunistic pathogens [0.03%]
医院污水的元基因组分析：全国范围内的抗菌药物耐药基因和机会致病菌的综合分析
Reshma Silvester,William B Perry,Gordon Webster et al.
Reshma Silvester et al.
Background: Healthcare settings are recognised as potential hotspots for the emergence and spread of antimicrobial resistance (AMR). Method: ...
Symptom Burden and Post-COVID-19 Syndrome 24 Months Following SARS-CoV-2 Infection: Longitudinal Population-Based Study [0.03%]
基于纵向人口的调查：感染SARS-CoV-2后24个月的症状负担和新冠肺炎后遗症
Raphael S Peter,Lisamaria Eble,Alexandra Nieters et al.
Raphael S Peter et al.
Objectives: To describe the symptom burden and associated impairment two years after SARS-CoV-2 index infection. Methods: Participants ...
Impact of co-infection with SARS-CoV-2 and other respiratory viruses on illness: Pooled analyses of 11 COVID-19 cohorts [0.03%]
SARS-CoV-2与其它呼吸道病原体共同感染对疾病进展的影响：来自11个新冠队列的汇总分析
Marieke LA de Hoog,Emma Sem Hauser-van Westrhenen,Angelique Mam Winkel et al.
Marieke LA de Hoog et al.
Objective: This individual patient data meta-analysis investigates the impact of SARS-CoV-2 infection with or without other respiratory viruses on Acute Respiratory Illness (ARI) occurrence and severity. ...
Superior Antiviral Efficacy of Combined 3CL Protease and RdRp Inhibition Compared to 3CL Protease Inhibitor Monotherapy in Hospitalized COVID-19 Patients [0.03%]
与单用3CL蛋白酶抑制剂相比，3CL蛋白酶和RdRp联合抑制治疗对住院COVID-19患者的抗病毒疗效更佳
Yuan Gao,Jiaying Zhang,Muxin Liu et al.
Yuan Gao et al.
Epidemiological and genomic characterisation of an outbreak of Streptococcus pyogenes emm5.23 [0.03%]
emm5.23型A群链球菌流行病学和基因组特征分析
Davide Pagnossin,Andrew Smith,William Weir et al.
Davide Pagnossin et al.
Objectives: This retrospective cross-sectional study examined the epidemiology, clinical presentations, and genomics of Streptococcus pyogenes genotype emm5.23, linked to severe outcomes in Scotland. ...