Within-host evolution of tandemly duplicated blaKPC-14 conferring cross-resistance to ceftazidime-avibactam, cefiderocol and aztreonam-avibactam in hypervirulent ST11 Klebsiella pneumoniae [0.03%]
在高毒力ST11型肺炎克雷伯菌中，串联重复的blaKPC-14基因的体内进化导致对 ceftazidime- avibactam、cebiderocol 和 aztreonam-avibactam 耐药性交叉抵抗
Fuyao Hu,Yi Zhang,Mingju Hao et al.
Fuyao Hu et al.
Objectives: Hypervirulent carbapenem-resistant Klebsiella pneumoniae (hv-CRKP) exhibiting cross-resistance to multiple antimicrobial agents represents a formidable therapeutic challenge. Therefore, elucidating the mechani...
Hospitalizations and deaths from major respiratory viruses in the US: An ensemble time series modeling study, 2016-2025 [0.03%]
2016年至2025年美国主要呼吸道病毒的住院和死亡病例数量的时间序列建模研究
Chelsea L Hansen,Nabila Shaikh,Sarah Naeger et al.
Chelsea L Hansen et al.
Objective: To estimate the hospitalization and mortality impact of influenza, respiratory syncytial virus (RSV), human metapneumovirus (HMPV), rhino/enteroviruses (RV/EV), and SARS-CoV-2. ...
Evidence for a relationship between concentrations of nucleos/tide analogue agents and treatment outcome in chronic hepatitis B infection: A systematic review [0.03%]
核苷（酸）类似物浓度与慢性乙型肝炎治疗效果之间关系的证据：系统性综述
Gloria Sukali,Motswedi Anderson,Khadija Said Mohammed et al.
Gloria Sukali et al.
Introduction: Treatment of hepatitis B virus (HBV) infection primarily relies on nucleos(t)ide analogues to achieve viral suppression, with tenofovir or entecavir as first-line agents. Expanding treatment and improving it...
Streptococcus agalactiae bone and joint infection: a multicentre observational study 2014-23 [0.03%]
一项关于β-溶血性链球菌agalactiae骨和关节感染的多中心观察研究（2014-2023年）
Simon Jamard,Mathilde Jan,Gwenael LE Moal et al.
Simon Jamard et al.
Introduction: Streptococcus is the second genus involved in bone and joint infections (BJIs) after Staphylococcus. Streptococcus agalactiae is the predominant Streptococcus species implicated in BJIs. However, unlike Stap...
Respiratory viral detection in adult severe acute respiratory infection post-COVID-19 pandemic: implications for antimicrobial stewardship [0.03%]
新冠肺炎疫情后成人严重急性呼吸道感染中呼吸病毒的检测：抗菌药物管理的启示
Elen Vink,Michael E Murphy,Rory Gunson et al.
Elen Vink et al.
Objectives: To characterise epidemiology, management, and outcomes of adult severe acute respiratory infection (SARI) in the post-COVID-19 era using virological surveillance and linked clinical data, and to explore implic...
Home-Based Rapid Testing and Early Antiviral Treatment as a Potential Strategy to Blunt Pediatric Influenza Peak [0.03%]
家庭快速检测和早期抗病毒治疗作为潜在的儿科流感阻峰策略
Youran Li,Ting Zhang,Jie Gao
Youran Li
Landscape and ecological correlates of tick-associated viruses in Inner Mongolia, China [0.03%]
内蒙古的景观和生态与蜱传病毒的相关性研究
Chunfu Li,Jian Li,Rui Ma et al.
Chunfu Li et al.
Introduction: Ticks harbor complex RNA viromes containing both confirmed pathogens and numerous viruses with unknown transmission routes. Defining the diversity and ecological correlates of these viral communities is crit...
Age-associated impairment of humoral and cellular immune responses to SARS-CoV-2 in a large community cohort with hybrid immunity [0.03%]
在具有混合免疫的大型社区队列中，SARS-CoV-2对年龄相关性体液和细胞免疫反应的影响
Jinqiu Ran,Liguo Zhu,Mingzhe Ning et al.
Jinqiu Ran et al.
Objectives: To characterize SARS-CoV-2-specific humoral and cellular immunity in a large community cohort, focusing on age-related differences following hybrid immunity from prior infection and vaccination. ...