Machine learning identifies a 10-gene signature predicting hepatocellular carcinoma recurrence and immune-metabolic reprogramming [0.03%]
机器学习识别出一种由10个基因组成的特征可用于预测肝细胞癌的复发及免疫代谢重编程
Pritam Bera,Rajesh Raju,Debodipta Das
Pritam Bera
Background: Hepatocellular carcinoma (HCC) remains a major cause of cancer-related mortality, with frequent recurrence after curative treatment. Conventional clinicopathological prognostic systems fail to capture the mole...
The association between preoperative ROTEM-assessed hypercoagulability and postoperative pulmonary embolism in cytoreductive surgery and HIPEC: a single-site Bayesian analysis [0.03%]
基于单中心Bayesian分析的细胞减灭术和HIPEC围手术期高凝状态与术后肺栓塞相关性的研究
Daniel J Ahn,Gerhardus S Labuschagne,Natalie A Smith et al.
Daniel J Ahn et al.
Introduction: Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) is associated with high rates of postoperative pulmonary embolism (PE). Rotational thromboelastometry (ROTEM) can detect hyper...
Neoadjuvant chemotherapy for Lauren diffuse-type gastric cancer: Is it necessary? [0.03%]
拉恩弥漫型胃癌的新辅助化疗：有必要吗？
Bochen Lai,Zhizhong Xiong,Bin Zhong et al.
Bochen Lai et al.
Introduction: Lauren's diffuse-type adenocarcinoma is less sensitive to chemotherapy, whether neoadjuvant chemotherapy (NAC) benefits this subtype remains uncertain. ...
Development of S.Tool: An electronic diary for assessing bowel symptoms after rectal cancer surgery [0.03%]
S.Tool的开发：一种用于评估直肠癌术后排便症状的电子日记表的发展
L Lauwereins,A D&#x;Hoore,E Coeckelberghs et al.
L Lauwereins et al.
Introduction: Rectal cancer treatment has improved survival, but postoperative bowel dysfunction, known as Low Anterior Resection Syndrome (LARS), significantly impacts Quality of Life. However, current assessment tools l...
Preoperative CT-based topologically distinct intratumoral heterogeneity scores for predicting intratumoral tertiary lymphoid structures and outcomes in hepatocellular carcinoma: A multicenter study [0.03%]
基于术前CT的肿瘤内拓扑异质性评分在预测肝细胞癌瘤内三级淋巴结构和临床结局中的应用：多中心研究
Jinhong Zhao,Miaoping Zhou,Yongming Tan et al.
Jinhong Zhao et al.
Objectives: Intratumoral tertiary lymphoid structures (iTLSs) are prognostic biomarkers for hepatocellular carcinoma (HCC). This study aimed to develop a machine learning approach based on topologically distinct intratumo...
Biologic stratification with tumor burden score and CA19-9 to inform vascular resection in intrahepatic cholangiocarcinoma [0.03%]
基于肿瘤负荷评分和CA19-9的生物分层指导肝内胆管癌血管联合切除手术
Kizuki Yuza,Jun Kawashima,Odysseas P Chatzipanagiotou et al.
Kizuki Yuza et al.
Background: The prognostic impact of vascular resection in intrahepatic cholangiocarcinoma (iCCA) remains uncertain, particularly in the context of advanced disease requiring complex surgery. This study evaluated the asso...
Length of the proximal resection margin and survival after surgery for oesophageal cancer [0.03%]
食管癌手术的近端切缘长度与生存期的关系
Ellinor Wiström,Fredrik Mattsson,Eivind Gottlieb-Vedi et al.
Ellinor Wiström et al.
Background: While tumour-free (R0) margins are essential in oesophageal cancer surgery, the ideal length of the proximal resection margin remains unclear. Although longer margins may improve oncological outcomes, they can...
Corrigendum to "Long-term oncological outcomes after salvage surgery for anal squamous cell carcinoma - a national cohort study" [Eur J Surg Oncol 52 (2026) 111482] [0.03%]
“挽救手术治疗肛鳞细胞癌的长期肿瘤学结果——一项全国队列研究”的勘误表
Stephanie Jacobsen,Eva Angenete,Anders Johnsson et al.
Stephanie Jacobsen et al.
The rationale against a "mandatory" extended hepatectomy in perihilar cholangiocarcinoma: meta-analysis [0.03%]
peri-hilar胆管癌反对强制性扩大肝切除术的论据：meta分析
A M Bonomi,S Granieri,Bhea Ten Haaft et al.
A M Bonomi et al.
Introduction: Traditional surgical teaching includes an extended hepatectomy for patients diagnosed with perihilar cholangiocarcinoma (pCCA). However, recent studies suggest it may not consistently lead to the best outcom...
Predicting recurrence in patients with node-negative perihilar cholangiocarcinoma after an R0 resection [0.03%]
预测R0切除的局部淋巴结阴性肝门胆管癌患者复发风险
Tao Wei,Jian Zhang,Odysseas P Chatzipanagiotou et al.
Tao Wei et al.
Background: Resection margin status and lymph node involvement are well-established predictors of recurrence following resection of perihilar cholangiocarcinoma (pCCA). However, even patients with favorable pathology incl...