Manuel Monreal,Javier Trujillo-Santos
Manuel Monreal
Patients with venous thromboembolism (VTE) and active cancer are often excluded from clinical trials of anticoagulant therapy because of short life expectancy, inability or unwillingness to attend for regular laboratory monitoring during vi...
Ted Wun,Richard H White
Ted Wun
Recent studies have better defined the epidemiology of venous thromboembolism (VTE) in cancer patients. The incidence is highest in patients who have metastatic disease at the time of presentation and who have fast growing, biologically agg...
Maria Benedetta Donati
Maria Benedetta Donati
In this introductory chapter a story has been reviewed concerning the evolution of the concept of "cancer and thrombosis", since its first description by Armand Trousseau in 1865. From scattered reports on experimental material (tumor extra...
Cancer and thrombosis [0.03%]
癌症与血栓形成
Benjamin Brenner
Benjamin Brenner
What are the most important donor and recipient factors affecting the outcome of related and unrelated allogeneic transplantation? [0.03%]
同种异体移植中，哪些供者和受者的因素最重要？
Claudio Anasetti
Claudio Anasetti
Several recipient and donor risk factors affect outcome after transplantation with allogeneic hematopoietic stem cells. The most important recipient risk factors are patient age, comorbidity, performance status, cytomegalovirus (CMV) status...
Diagnosis and therapy of fungal infection in patients with leukemia--new drugs and immunotherapy [0.03%]
急性白血病患者真菌感染的诊断与治疗——新药和免疫疗法
Elias J Anaissie
Elias J Anaissie
Invasive fungal infections (IFIs) are a common problem in immunocompromised patients. Patients with leukemia, especially those undergoing stem cell transplantation, are at increased risk for IFIs, particularly invasive aspergillosis (IA). S...
James L M Ferrara
James L M Ferrara
The principal cause of mortality and morbidity following hematopoietic cell transplantation (HCT) is graft-versus-host disease (GVHD). Studies in murine models have revealed that inflammatory mediators such as tumor necrosis factor-alpha (T...
What is the impact of hematopoietic cell transplantation (HCT) for older adults with acute myeloid leukemia (AML)? [0.03%]
造血干细胞移植(HCT)对急性髓系白血病(AML)老年患者的疗效和安全性分析
Frederick R Appelbaum
Frederick R Appelbaum
Acute myeloid leukemia (AML) patients over the age of 55 years are generally more difficult to treat than younger patients due to intrinsic drug resistance and diminished tolerance to treatment. The unfortunate result is that conventional c...
Martin S Tallman
Martin S Tallman
Acute promyelocytic leukemia (APL), a highly curable subtype of acute myeloid leukemia (AML) is characterized by the chromosomal translocation t(15;17) and, consequently, the presence of the PML-RARalpha fusion transcript. Most patients are...
Is asparaginase a critical component in the treatment of acute lymphoblastic leukemia? [0.03%]
异亮氨酸脷酶在急性淋巴细胞白血病治疗中是否必需？
Dan Douer
Dan Douer
The outcome of pediatric acute lymphoblastic leukemia (ALL) has improved dramatically over the last 40 years through a systematic approach of well-designed large trials including use of asparaginase. Although asparaginase has been incorpora...