Immunopathogenic mechanisms and modulatory approaches to graft-versus-host disease prevention in acute myeloid leukaemia [0.03%]
急性髓系白血病移植物抗宿主病的免疫病理机制及预防调节方法
Yifan Pang,Noa G Holtzman
Yifan Pang
Allogeneic haematopoietic stem cell transplantation (HSCT) remains the only potential cure for intermediate to high-risk acute myeloid leukaemia (AML). The therapeutic effect of HSCT is largely dependent on the powerful donor-derived immune...
Gray Magee,Brittany Knick Ragon
Gray Magee
Allogeneic hematopoietic cell transplantation (HCT) is a curative treatment modality for select patients with acute myeloid leukemia (AML), functioning as a restorative agent following intensified chemo- and/or radiotherapy and also engende...
Dermatologic complications in transplantation and cellular therapy for acute leukemia [0.03%]
移植和细胞疗法治疗急性白血病的皮肤病并发症
Shahab Babakoohi,Stephanie L Gu,Hamid Ehsan et al.
Shahab Babakoohi et al.
Adoptive cellular immunotherapy, mainly hematopoietic stem cell transplant and CAR-T cell therapy have revolutionized treatment of patients with acute leukemia. Indications and inclusion criteria for these treatments have expanded in recent...
Edouard F Bonneville,Johannes Schetelig,Hein Putter et al.
Edouard F Bonneville et al.
Missing data are frequently encountered across studies in clinical haematology. Failure to handle these missing values in an appropriate manner can complicate the interpretation of a study's findings, as estimates presented may be biased an...
Worldwide sources of data in haematology: Importance of clinician-biostatistician collaboration [0.03%]
全球血液学数据来源：临床医生-生物统计学家合作的重要性
Kristin M Page,Stephen R Spellman,Brent R Logan
Kristin M Page
The field of haematology has benefitted greatly from registry-based observational research. Medical and technical advances, changes in regulations and events such as the global pandemic is changing the landscape for registries. This review ...
Diagnosis and management of post-transplant lymphoproliferative disease following solid organ transplantation in children, adolescents, and young adults [0.03%]
儿童、青少年和年轻成人实体器官移植后淋巴增生性疾病的相关诊断和处理指南
Jeremy Rubinstein,Keri Toner,Thomas Gross et al.
Jeremy Rubinstein et al.
Post-transplant Lymphoproliferative Disease (PTLD) remains a major complication of solid organ transplantation (SOT) in pediatric patients. The majority are Epstein-Barr Virus (EBV) driven CD20+ B-cell proliferations responsive to reduction...
Diagnosis and management of ALK-positive anaplastic large cell lymphoma in children and adolescents [0.03%]
儿童和青少年间变性大细胞淋巴瘤ALK阳性诊断与治疗专家共识声明
Charlotte Rigaud,Fabian Knörr,Laurence Brugières et al.
Charlotte Rigaud et al.
Anaplastic lymphoma kinase (ALK)-positive anaplastic large cell lymphoma (ALCL) is a CD30-positive T cell lymphoma characterized by signalling from constitutively activated ALK fusion proteins. Most children and adolescents present in advan...
Late effects and frontline treatment selection for children with non-Hodgkin lymphoma [0.03%]
儿童非霍奇金淋巴瘤的后遗症和一线治疗选择
Matthew J Ehrhardt,Stephanie B Dixon,Jennifer Belsky et al.
Matthew J Ehrhardt et al.
Approximately 1 in 640 adults between 20 and 40 years of age is a survivor of childhood cancer. However, survival has often come at the expense of increased risk of long-term complications, including chronic health conditions and higher mor...
Diagnosis and management of lymphoblastic lymphoma in children, adolescents and young adults [0.03%]
儿童、青少年及年轻成人淋巴母细胞淋巴瘤的诊断和治疗
William C Temple,Stephanie Mueller,Michelle L Hermiston et al.
William C Temple et al.
Lymphoblastic lymphoma (LBL) is the second most common type of non-Hodgkin Lymphoma (NHL) in children, adolescents, and young adults (CAYA), accounting for 25-35% of all cases. T-lymphoblastic lymphoma (T-LBL) comprises 70-80% of cases, whi...
Diagnosis and management of cutaneous lymphomas and lymphoid proliferations in children, adolescents and young adults (CAYA) [0.03%]
儿童、青少年和青年人（CAYA）的皮肤淋巴瘤和淋巴增值性病变的诊断与治疗
Jamie Stokke,Annabelle Tann,Nader Kim El-Mallawany et al.
Jamie Stokke et al.
Cutaneous lymphomas and lymphoid proliferations (LPD) in children, adolescents, and young adults (CAYA) are a heterogeneous group of lymphoid neoplasms that present formidable diagnostic challenges to clinicians and pathologists alike. Alth...