Optimizing Vancomycin Exposure for Early Treatment Response in Very-Low-Birth-Weight Neonates With Late-Onset Sepsis [0.03%]
优化万古霉素暴露以实现极低出生体重早发感染新生儿的早期治疗反应
Manal Abouelkheir,Hekmat M El Magdoub,Zekra K Aljehani et al.
Manal Abouelkheir et al.
Background: Vancomycin is widely used to treat neonatal late-onset sepsis (LOS). However, its optimal pharmacokinetic/pharmacodynamic targets in neonates, particularly those with very low birth weight (VLBW), remain inade...
Respiratory Viral Detection and Invasive Bacterial Infections in Infants ≤90 Days [0.03%]
≤90天婴儿呼吸道病毒检测及其侵袭性细菌感染关系
Erin G Nicholson,Tess Stopczynski,Leila C Sahni et al.
Erin G Nicholson et al.
Background: Comprehensive data are needed to guide the use and interpretation of molecular respiratory viral testing in evaluating infants 0 to ≤90 days old for invasive bacterial infections (IBIs). We aimed to describe ...
Expanding the Role of Dalbavancin in Children: A Case Series and Systematic Review [0.03%]
达拉巴万辛在儿童中的应用扩展：一例系列和系统性综述
Victoria Domínguez-León,María José Muñoz-Vilches,Concepción Álvarez Del Vayo Benito et al.
Victoria Domínguez-León et al.
Background: Dalbavancin is a long-acting lipoglycopeptide antibiotic with activity against Gram-positive bacteria and is approved for the treatment of acute bacterial skin and skin structure infections. Its pharmacokineti...
Pathogens in the Nasopharynx Before and After Antibiotic Treatment for Acute Otitis Media [0.03%]
急性中耳炎抗生素治疗前后鼻咽部病原体变化
Hanna Björn,Nader Shaikh,Miia K Laine et al.
Hanna Björn et al.
Background: Limited data exist on whether the timing or duration of treatment for acute otitis media (AOM) affects nasopharyngeal carriage. We studied the eradication of pathogens (Streptococcus pneumoniae, Haemophilus in...
From Pharyngitis to Status Epilepticus: When EBV Invades the Central Nervous System [0.03%]
从咽炎到癫痫持续状态：EB病毒感染中枢神经系统的病例报告
Júlia Abud Monteiro,Daniel Jarovsky,Mariana Volpe Arnoni et al.
Júlia Abud Monteiro et al.
Clinical and Economic Burden of Complicated Pneumonia and Invasive Disease due to Streptococcus pneumoniae Serotype 19A in an Ecuadorian Pediatric Reference Hospital [0.03%]
厄瓜多尔一家儿科医院肺炎链球菌19A血清型复杂性肺炎和侵袭性疾病的相关临床与经济负担
Elías David Salgado-Villalba,Ángeles Costta-Michuy,Ximena Del Rosario Villalba-Valencia et al.
Elías David Salgado-Villalba et al.
Serotype 19A has emerged as an important cause of pneumococcal disease following the introduction of the 10-valent pneumococcal conjugate vaccine (PCV10). In this retrospective study of children hospitalized with culture-confirmed invasive ...
Early-Life Antibiotic Exposure Disrupts Bifidobacterium in Infants: A qPCR-Based Cohort Study [0.03%]
婴儿早期抗生素暴露会扰乱肠道乳双歧杆菌：基于qPCR的队列研究
Dina Mohammed Abdel-Hady,Mayada Sabry Zeid,Eman Hamdy Mohamed et al.
Dina Mohammed Abdel-Hady et al.
Background: Early infancy represents a critical window for establishing the gut microbiome, during which Bifidobacterium species dominate and play essential roles in metabolic, immune and intestinal maturation. Antibiotic...
Underestimation of Disease Severity Using WHO Criteria for Nonsevere Tuberculosis in Children in a Low-Prevalence, High-Resource Setting: Evidence From an Italian Cohort [0.03%]
在低结核病流行、高资源设置中使用WHO标准会导致儿童非重症结核病患者病情被低估的证据：来自意大利队列的证据
Nasim Taheri,Marco Denina;OIRM-TB study group
Nasim Taheri
Bundibugyo Virus Disease in 2026: Clinical and Public Health Responses [0.03%]
2026年的 Bundibugyo 型病毒病的临床和公共卫生应对措施
Robert J Leggiadro
Robert J Leggiadro
Management of Invasive Group A Streptococcal Four Infections in Children: The European Society for Pediatric Infectious Disease Guidelines [0.03%]
儿童侵袭性A群链球菌感染的管理：欧洲儿科感染性疾病协会指南
Elena Chiappini,Roberta Pellegrino,Irene Dalpiaz et al.
Elena Chiappini et al.
Background: Invasive group A streptococcal (iGAS) infections in children, although rare, are associated with significant morbidity and mortality, and their incidence has risen globally in recent years. Evidence for optima...