Stephen A McClave,Keith R Miller,Robert G Martindale
Stephen A McClave
Purpose of review: Provision of adequate protein in the nutritional regimen remains a concern for clinicians in the intensive care setting, to counteract the accelerated catabolism, breakdown of skeletal muscle, and funct...
Uwe Zeymer,Dirk Westermann
Uwe Zeymer
Purpose of review: Despite improvements in reperfusion and adjunctive therapies cardiogenic shock associated with acute myocardial infarction is still associated with a mortality of 40-50%. Therefore, mechanical circulato...
A 'Direct to operating room' approach improves critically injured patient outcomes [0.03%]
“直接送入手术室”的方式能够改善重症患者的结果
Phillip M Kemp Bohan,Jennifer M Leonard,Lewis J Kaplan
Phillip M Kemp Bohan
Purpose of review: This review explores the rationale and evidence supporting the 'direct to operating room (DTOR)' treatment paradigm to improve critically injured patient outcomes. We examine elements that impact DTOR s...
Guillaume Théry,Nadia Aissaoui,Olfa Hamzaoui
Guillaume Théry
Purpose of review: The understanding of cardiogenic shock (CS) has significantly evolved over the past decades. Initially regarded as a purely mechanistic syndrome, CS is now recognized as a multifaceted condition that in...
Enriching patient populations in ICU trials: reducing heterogeneity through machine learning [0.03%]
重症监护试验中利用机器学习减少异质性来丰富患者人群
Wonsuk Oh,Marinela Veshtaj,Ankit Sakhuja
Wonsuk Oh
Purpose of review: Despite the pivotal role of randomized controlled trials (RCTs) in critical care research, many have failed to demonstrate significant benefits, particularly in nutrition interventions. This review high...
Biologic rationale and evidence for high-dose hydroxocobalamin in septic shock [0.03%]
Septic休克高剂量羟钴胺素的生物学依据和证据
Jayshil J Patel,Jason Carr,Rodney Willoughby
Jayshil J Patel
Purposes of review: The inflammatory response in sepsis raises circulatory levels of gaseous transmitters (gasotransmitters) nitric oxide (NO) and hydrogen sulfide (H2S), both of which generate and sustain septic shock. C...
Luca Baldetti,Lorenzo Cianfanelli,Anna Mara Scandroglio
Luca Baldetti
Purpose of review: After more than 50 years from its invention, the intra-aortic balloon pump (IABP) is still one of the most widely used mechanical circulatory support devices to treat cardiogenic shock (CS). This review...
Grégoire Del Marmol,Quentin Moyon,Alain Combes
Grégoire Del Marmol
Purpose of review: Temporary circulatory support (TCS) devices play a crucial role in stabilizing patients with refractory cardiogenic shock. They provide essential hemodynamic support and serve as a bridge to recovery, d...
Microaxial flow-pump support in patients with cardiogenic shock: a review of the literature [0.03%]
微轴流泵在心源性休克患者中的应用：文献综述
Tobias T Krause,Nikos Werner,Juergen Leick
Tobias T Krause
Purpose of review: The purpose of this review is to summarize the current evidence in the treatment of patients with cardiogenic shock focusing on the use of microaxial flow pump (mAFP) support. ...
Exploring the role of glucagon-like peptide-1 receptor agonists in critical illness: mechanisms, benefits, and clinical implications [0.03%]
GLP-1受体激动剂在危重症中的作用：机制、益处和临床意义
Vidit G Jogani,Osman Mohamed Elfadil,Jithinraj Edakkanambeth Varayil et al.
Vidit G Jogani et al.
Purpose of review: This review aims to synthesize current evidence on the expanding role of glucagon-like peptide-1 (GLP-1) receptor agonists (RAs) beyond glycemic control, particularly in the context of critical illness....