Luana Fianchi,Martina Quattrone,Livio Pagano
Luana Fianchi
Purpose of review: Invasive mold infections (IMIs) remain a major cause of morbidity and mortality in patients with hematological malignancies, particularly when critical illness develops. Advances in hematological therap...
Providing appropriate response-contingent phase-specific nutrition therapy in critical illness [0.03%]
重症患者个体化阶段性营养治疗的实施
Stephen A McClave,Robert G Martindale,Jayshil J Patel
Stephen A McClave
Purpose of review: The pathogenesis of critical illness drives a dynamic cascade of clinical, metabolic, and immunologic abnormalities through the course of disease. Recent randomized trials show that early full-dose feed...
Predicting, describing, or measuring? How to align model purpose with validity and applicability in critical care outcome research [0.03%]
预测、描述还是测量？如何在重症监护结果研究中使模型目的与有效性和适用性保持一致
Alexander Tracy,Aasiyah Rashan,Otavio Ranzani
Alexander Tracy
Purpose of review: Clinical models are commonly applied in critical care for both descriptive and predictive purposes. However, methodological rigour is often lacking in their development and validation. This review exami...
Individualizing post-ICU nutrition: from guideline intent to bedside practice [0.03%]
从指南建议到临床实践：个体化重症监护病房患者的营养管理
Oona Leemans,Zenzi Rosseel,Claude Pichard et al.
Oona Leemans et al.
Purpose of review: Survivorship of critical illness has increased, shifting attention toward recovery and long-term outcomes. Post-ICU nutrition is emerging as a clinically relevant, yet underperforming contributor to fun...
Jesse Crayle,Baback Arshi
Jesse Crayle
Purpose of review: This manuscript provides an overview of common and uncommon central nervous system (CNS) infections seen in intensive care settings. Re...
Septic shock [0.03%]
感染性休克
Elizabeth Twichell,Lauren Sattler,Dan Reynolds
Elizabeth Twichell
Purpose of review: This review aims to provide a summary of recent updates in resuscitation and vasopressor strategies for septic shock, as well as advancements in precision therapy. ...
The impact of age, prior health status, and frailty on outcome prediction in critical care [0.03%]
年龄、合并症和衰弱对重症监护预后预测的影响
Hans Flaatten,Michael Beil,Bertrand Guidet
Hans Flaatten
Purpose of review: We highlight publications from the year 2025 that examined the contribution of age, frailty, and chronic conditions to outcomes in ICU patients aged 80 years and older. Traditional prediction models are...
Severe community-acquired pneumonia: a paradigm shift toward precision diagnostics, microbiology, and targeted management [0.03%]
社区获得性肺炎：向精准诊断、微生物学和个体化治疗转变
Ignacio Martin-Loeches,Marcos I Restrepo,Antoni Torres
Ignacio Martin-Loeches
Purpose of review: Severe community-acquired pneumonia (sCAP) remains one of the most lethal infectious syndromes in critical care, with mortality remaining persistently high despite decades of antimicrobial and supportiv...
Jorge I F Salluh,Amanda Quintairos,Dave A Dongelmans et al.
Jorge I F Salluh et al.
Purpose of review: National ICU benchmarking systems are critical infrastructure for evaluating and improving the quality of critical care across all settings. This review summarizes the recent literature on establishing,...
Michelle S Chew
Michelle S Chew