A critical review of front-loading: A maladaptive drinking pattern driven by alcohol's rewarding effects [0.03%]
前置饮酒批判性述评：一种由酒精欣快作用驱动的适应不良型饮酒模式
Cherish E Ardinger,Christopher C Lapish,Cristine L Czachowski et al.
Cherish E Ardinger et al.
Front-loading is a drinking pattern in which alcohol intake is skewed toward the onset of reward access. This phenomenon has been reported across several different alcohol self-administration protocols in a wide variety of species, includin...
A double-hit model reveals individual and synergic consequences of prenatal and adolescent postnatal ethanol exposure [0.03%]
双重模型揭示了孕期和青春期后乙醇暴露的个体及协同作用后果
Ricardo Marcos Pautassi,María Carolina Fabio
Ricardo Marcos Pautassi
Hepatic CYP2B10 is highly induced by binge ethanol and contributes to acute-on-chronic alcohol-induced liver injury [0.03%]
急性酒精过量诱导肝CYP2B10表达并促进慢性饮酒诱发的急性肝损伤发生发展
Bryan Mackowiak,Mingjiang Xu,Yuhong Lin et al.
Bryan Mackowiak et al.
Background: The chronic-plus-binge model of ethanol consumption, where chronically (8-week) ethanol-fed mice are gavaged a single dose of ethanol (E8G1), is known to induce steatohepatitis in mice. However, how chronicall...
Risk factors and protective factors for alcohol-related liver disease: A systematic review and meta-analysis [0.03%]
饮酒相关肝病的风险因素和保护因素：系统回顾和meta分析
Ru Zhang,Zongzhe Tang,Wenjie Xu et al.
Ru Zhang et al.
Background: Although alcohol-related liver disease (ALD) is a global health threat, there are no specific effective treatments for it. Thus, efforts at preventing ALD are important and could be enhanced by using strategie...
Prenatal alcohol exposure exacerbates acute sensorimotor deficits and impedes long-term behavioral recovery from the effects of an adult-onset cerebrovascular ischemic stroke [0.03%]
宫内酒精暴露加剧成人期缺血性卒中急性感觉运动缺陷并阻碍长期行为恢复
Shameena Bake,David A Hurst,Rajesh C Miranda et al.
Shameena Bake et al.
Background: Prenatal alcohol exposure (PAE) is a significant risk factor for developmental disability, although its health consequences across the lifespan are poorly understood. Here, we hypothesized that latent brain an...
Temporal trends in alcohol, cannabis, and simultaneous use among 12th-grade U.S. adolescents from 2000 to 2020: Differences by sex, parental education, and race and ethnicity [0.03%]
美国高中生从2000年到2020年的酒精、大麻以及同时使用情况的性别、父母教育程度和种族/族裔差异分析
Katherine M Keyes,Navdep Kaur,Noah T Kreski et al.
Katherine M Keyes et al.
Background: Simultaneous use of alcohol and cannabis to enhance each other's effect can cause potential harm. Time trends are diverging in adolescent use of alcohol, which is declining, and cannabis, which is increasing a...
2-Arachidonoylglycerol-mediated endocannabinoid signaling modulates mechanical hypersensitivity associated with alcohol withdrawal in mice [0.03%]
大麻素信号转导调节小鼠酒精戒断相关的机械性疼痛过敏反应
Amanda Morgan,Danielle Adank,Keenan Johnson et al.
Amanda Morgan et al.
Background: Alcohol use disorder (AUD) commonly occurs in patients with chronic pain, and a major barrier to achieving abstinence and preventing relapse is the emergence of hyperalgesia during alcohol withdrawal. Elucidat...
The role of alcohol and cannabis co-use in drinking rate and its impact on consequences [0.03%]
酒精和大麻共用在饮酒速度及其对后果的影响中的作用
Rachel L Gunn,Alexander W Sokolovsky,Megan M Drohan et al.
Rachel L Gunn et al.
Background: The impact of alcohol and cannabis co-use on college student drinking and related outcomes is complex. Specific characteristics or patterns of co-use events beyond drinking quantity may be important to the exp...
Analysis of alcohol use, consumption of micronutrient and macronutrients, and liver health in the 2017-2018 National Health and Nutrition Examination Survey [0.03%]
基于2017-2018年美国国家健康和营养检查调查的饮酒、微量及宏量营养素摄入与肝脏健康的分析研究
Jeffrey B Warner,Kara H Zirnheld,Huirong Hu et al.
Jeffrey B Warner et al.
Background: Alcohol use is a major global healthcare burden that contributes to numerous adverse health outcomes, including liver disease. Many factors influence individual susceptibility to alcohol-associated diseases, i...
Alcohol use, physical activity, and muscle strength moderate the relationship between body composition and frailty risk among people living with HIV [0.03%]
酒精使用、身体活动和肌肉力量对机体组成与HIV患者脆弱风险关系的调节作用
Danielle E Levitt,Liz Simon,Hui-Yi Lin et al.
Danielle E Levitt et al.
Background: Antiretroviral therapy has improved life expectancy among people living with HIV (PLWH). Despite increased longevity, PLWH are at increased risk of age-related comorbidities, including frailty. We examined the...