All-cause and liver-related mortality risk factors in excessive drinkers: Analysis of data from the UK biobank [0.03%]
英国生物样本库中大量饮酒者全因和肝病死亡的危险因素分析
John B Whitfield,Devanshi Seth,Timothy R Morgan;GenomALC Consortium
John B Whitfield
Background: High alcohol intake is associated with increased mortality. We aimed to identify factors affecting mortality in people drinking extreme amounts of alcohol. ...
Role of the ghrelin system in alcohol use disorder and alcohol-associated liver disease: A narrative review [0.03%]
生长激素释放肽系统在酒精使用障碍和酒精相关肝病中的作用：叙述性综述
Kusum K Kharbanda,Mehdi Farokhnia,Sara L Deschaine et al.
Kusum K Kharbanda et al.
Unhealthy alcohol consumption is a global health problem. Adverse individual, public health, and socioeconomic consequences are attributable to harmful alcohol use. Epidemiological studies have shown that alcohol use disorder (AUD) and alco...
Alcohol-related dysmorphic features as predictors of neurodevelopmental delay in infants and preschool-aged children: Results from a birth cohort in Ukraine [0.03%]
饮酒所致面容异常与乌克兰出生队列中婴幼儿期神经发育迟缓的关系
Gretchen Bandoli,Claire Coles,Julie Kable et al.
Gretchen Bandoli et al.
Background: Cardinal and non-cardinal dysmorphic features are associated with prenatal alcohol exposure (PAE); however, their association with neurodevelopment is less clear. The objective of this study was to determine w...
Effects of ethanol on GluN1/GluN2A and GluN1/GluN2B NMDA receptor-ion channel gating kinetics [0.03%]
乙醇对谷氨酸N-甲基-D-天冬氨酸受体-GluN1/GluN2A和GluN1/GluN2B亚型离子通道门控动力学的影响
Robert W Peoples,Hong Ren
Robert W Peoples
Background: The N-methyl-D-aspartate receptor (NMDAR) is a major molecular target of alcohol action in the central nervous system, yet many aspects of alcohol's modulation of the activity of this ion channel remain unclea...
Paternal alcohol exposure has task- and sex-dependent behavioral effect in offspring [0.03%]
父饮酒对后代的行为具有任务和性别依赖性的影响
Steven J Nieto,Mark J Harding,David A Nielsen et al.
Steven J Nieto et al.
Background: Endophenotypes for alcohol use disorder are well known and may reflect paternal exposure effects passed down to offspring via epigenetic mechanisms. Previously, we showed that paternal alcohol exposure prior t...
Alcohol impairs recognition and uptake of Mycobacterium tuberculosis by suppressing toll-like receptor 2 expression [0.03%]
酒精通过抑制 Toll 样受体 2 的表达来干扰对结核杆菌的识别和摄取
Gregory W Wigger,Darya Khani,Mariam Ahmed et al.
Gregory W Wigger et al.
Background: Alcohol impairs pulmonary innate immune function and is associated with an increased risk of tuberculosis (TB). Toll-like receptor 2 (TLR2) is a pattern recognition receptor on alveolar macrophages that recogn...
Genetic and environmental etiology of drinking motives in college students [0.03%]
大学生饮酒动机的遗传和环境病因学研究
Jeanne E Savage,Roseann E Peterson,Fazil Aliev;Spit for Science Working Group;Danielle M Dick
Jeanne E Savage
Background: Drinking motives are robust proximal predictors of alcohol use behaviors and may mediate distinct etiological pathways in the development of alcohol misuse. However, little is known about the genetic and envir...
Cultural identity affiliation and alcohol use and related consequences among American Indian and White adolescents: A latent profile analysis [0.03%]
美国原住民和白人青少年的文化身份认同与饮酒行为及后果：潜在类别分析
Melissa R Schick,Alana Egan,Michael Crawford et al.
Melissa R Schick et al.
Background: Adolescent alcohol use is a significant public health concern and rates of alcohol use are higher among American Indian (AI) adolescents than national samples of non-AI youth. A potential factor in understandi...
Development and validation of the Alcoholic Beverage Identification Deep Learning Algorithm version 2 for quantifying alcohol exposure in electronic images [0.03%]
酒精饮料识别深度学习算法版本2的开发与验证：量化电子图像中酒精暴露量
Abraham Albert Bonela,Zhen He,Thomas Norman et al.
Abraham Albert Bonela et al.
Background: Seeing alcohol in media has been demonstrated to increase alcohol craving, impulsive decision-making, and hazardous drinking. Due to the exponential growth of (social) media use it is important to develop algo...