Diphencyprone Treatment of Alopecia Areata: Postulated Mechanism of Action and Prospects for Therapeutic Synergy with RNA Interference [0.03%]
用于治疗斑秃的二氢松香酯药物的作用机理及与RNA干扰联合用药的前景展望
Karen G Bulock,James P Cardia,Pamela A Pavco et al.
Karen G Bulock et al.
Diphencyprone (DPCP) is a potent topical sensitizing agent that has been used since the late 1970s by physicians for the treatment of alopecia areata (AA), viral warts (human papillomavirus) and cutaneous metastases of melanoma. Although to...
Therapy for Alopecia Areata in Mice by Stimulating the Hair Cycle with Parathyroid Hormone Agonists Linked to a Collagen-Binding Domain [0.03%]
甲状旁腺激素受体激动剂结合层粘连蛋白非胶原区城肽治疗小鼠斑秃通过促进毛发生长周期实现
Ranjitha Katikaneni,Andrew W Seymour,Rohan Gulati et al.
Ranjitha Katikaneni et al.
Alopecia areata is a common disorder in which autoimmune destruction of hair follicles results in patchy hair loss. Currently there is no adequate therapy, although immune modulator therapies are currently in development. Parathyroid hormon...
Toward the Clonotype Analysis of Alopecia Areata-Specific, Intralesional Human CD8+ T Lymphocytes [0.03%]
向百日咳博德特氏菌五聚血凝素PT的抗原识别克隆型分析脱发性疾病特异性的皮损内人CD8+T淋巴细胞
Marta Bertolini,Youhei Uchida,Ralf Paus
Marta Bertolini
Alopecia areata (AA) is an organ-restricted autoimmune disease that mainly affects the hair follicle (HF). Several findings support a key primary effector role of CD8+ T cells in the disease pathogenesis. Autoreactive CD8+ T cells are not o...
Overview of AA and Research Progress: What Have We Learned and Where Are We Headed? [0.03%]
AA概览及研究进展:我们已经了解了什么?未来的研究方向又如何?
David A Norris
David A Norris
During its 25th anniversary year, the National Alopecia Areata Foundation undertook a project to completely re-evaluate their research program and to help focus and direct future directions of alopecia areata research to better meet the goa...
From Targets to Treatments: Bridging Autoimmune Research to Advance Understanding of Alopecia Areata [0.03%]
从靶点到疗法:连接自身免疫研究以增进对斑秃的理解
Dory Kranz,Abby Ellison,Jeffrey A Frelinger et al.
Dory Kranz et al.
Alopecia areata is a common autoimmune skin disease resulting in the loss of hair on the scalp and elsewhere on the body that affects over 146 million people worldwide at some point in their lives. Founded in 1981, the National Alopecia Are...
The Contribution of Meta-Analysis of Genome-Wide Association Studies in Investigating the Genetic Susceptibility to Lupus [0.03%]
基因组范围关联研究的元分析在探究狼疮遗传易感性中的贡献
Yujun Sheng,Xianyong Yin,Yong Cui et al.
Yujun Sheng et al.
Qianqian Wang,Xiuxiu Wang,Leihong Xiang
Qianqian Wang
Jinping Gao,Liangdan Sun,Xuejun Zhang
Jinping Gao
Xiao-Yong Man,Min Zheng
Xiao-Yong Man
Yihua Cai,Lanqi Wang,Xia Li et al.
Yihua Cai et al.