Clinical Efficacy of Diphenylcyclopropenone in Alopecia Areata: Retrospective Data Analysis of 50 Patients [0.03%]
二苯环丙烯酮治疗斑秃的临床疗效分析——50例回顾性研究
Katherine S Chiang,Natasha A Mesinkovska,Melissa P Piliang et al.
Katherine S Chiang et al.
Diphenylcyclopropenone (DPCP) is widely considered the most effective topical immunotherapy for refractory or extensive alopecia areata (AA), but questions regarding how long to try DPCP therapy before terminating and what factors are progn...
Alicia M Stallings,Mara Weinstein Velez,Lori A Fiessinger et al.
Alicia M Stallings et al.
There is insufficient data in the literature concerning optimal intralesional kenalog (ILK) dosing for the treatment of alopecia areata (AA). The purpose of this pilot study was to evaluate the utility of using the ratio of ILK received to ...
Maria K Hordinsky
Maria K Hordinsky
Selection of a therapy for a patient with alopecia areata (AA) is frequently based on the age of the patient, disease extent, perhaps disease duration, patient expectations, cost of therapy in terms of time commitment, and financial resourc...
Maria E Beckett
Maria E Beckett
Alopecia areata is not a life-threatening disease, but it is absolutely life-altering. Alopecia areata can wreak havoc on a person's self-esteem at any age. Since the appearance of my first bald spot more than 35 years ago, millions have be...
The Use of the Immune Epitope Database to Study Autoimmune Epitope Data Related to Alopecia Areata [0.03%]
免疫表位数据库在研究与斑秃相关的自身免疫表位数据中的应用
Alessandro Sette,Sinu Paul,Kerrie Vaughan et al.
Alessandro Sette et al.
The Immune Epitope Database (IEDB) is a repository of published epitope data for infectious diseases, allergy, transplantation and autoimmunity. Herein we provide an introduction to the IEDB search interface, focusing on data related to aut...
Jeffrey A Frelinger
Jeffrey A Frelinger
High-throughput assays have begun to revolutionize modern biology and medicine. The advent of cheap next-generation sequencing (NGS) has made it possible to interrogate cells and human populations as never before. Although this has allowed ...
Integration of the Transcription Factor-Regulated and Epigenetic Mechanisms in the Control of Keratinocyte Differentiation [0.03%]
transcription因子调控和表观遗传机制在控制角质细胞分化中的整合
Vladimir A Botchkarev
Vladimir A Botchkarev
The epidermal differentiation program is regulated at several levels including signaling pathways, lineage-specific transcription factors, and epigenetic regulators that establish well-coordinated process of terminal differentiation resulti...
Excavating the Genome: Large-Scale Mutagenesis Screening for the Discovery of New Mouse Models [0.03%]
基因组筛选：大规模突变筛查以发现新的鼠模型
John P Sundberg,Soheil S Dadras,Kathleen A Silva et al.
John P Sundberg et al.
Technology now exists for rapid screening of mutated laboratory mice to identify phenotypes associated with specific genetic mutations. Large repositories exist for spontaneous mutants and those induced by chemical mutagenesis, many of whic...
John P Sundberg,Kevin McElwee,Michael A Brehm et al.
John P Sundberg et al.
Disease is not limited to humans. Rather, humans are but another mammal in a continuum, and as such, often share similar if not identical diseases with other mammalian species. Alopecia areata (AA) is such a disease. Natural disease occurs ...
Mechanisms of LtxA (Leukotoxin), a Potent New Anti-Inflammatory Agent for the Treatment of Alopecia Areata [0.03%]
LtxA（白细胞毒素）是一种新型治疗斑秃的强效抗炎剂及其作用机制研究
Scott C Kachlany
Scott C Kachlany
Alopecia areata is an autoimmune condition where activated, pro-inflammatory white blood cells (WBCs) attack the hair follicles, resulting in hair loss. Migration of these activated WBCs from the blood stream and into the follicle tissue re...