Inorganic-Organic Nanocomposite Assembly Using Collagen as Template and Sodium Tripolyphosphate as A Biomimetic Analog of Matrix Phosphoprotein [0.03%]
利用胶原作为模板和焦磷酸钠作为基质磷蛋白仿生模拟物的无机-有机纳米复合组装体
Lin Dai,Yi-Pin Qi,Li-Na Niu et al.
Lin Dai et al.
Nanocomposites created with polycarboxylic acid alone as a stabilization agent for prenucleation clusters-derived amorphous calcium phosphate exhibit non-periodic apatite deposition. In the present study, we report the use of inorganic poly...
Developing a Fluorescence-based Approach to Screening for Macromolecule Crystallization Conditions [0.03%]
开发一种用于大分子结晶条件荧光筛选方法
Marc L Pusey
Marc L Pusey
Current macromolecule crystallization screening methods rely on the random testing of crystallization conditions, in the hope that one or more will yield positive results, crystals. Most plate outcomes are either clear or precipitated solut...
Dianfan Li,Jean Lee,Martin Caffrey
Dianfan Li
The default lipid for the bulk of the crystallogenesis studies performed to date using the cubic mesophase method is monoolein. There is no good reason however, why this 18-carbon, cis-monounsaturated monoacylglycerol should be the preferre...
Development of an Automated High Throughput LCP-FRAP Assay to Guide Membrane Protein Crystallization in Lipid Mesophases [0.03%]
开发用于指导液晶相脂质中膜蛋白结晶的自动化高通量LCP-FRAP测定法
Fei Xu,Wei Liu,Michael A Hanson et al.
Fei Xu et al.
Crystallization in lipidic mesophases (in meso) has been successfully used to obtain a number of high-resolution membrane protein structures including challenging members of the human G protein-coupled receptor (GPCR) family. Crystallogenes...
What's in a drop? Correlating observations and outcomes to guide macromolecular crystallization experiments [0.03%]
一滴之见：通过观测和结果关联指导大分子结晶实验
Joseph R Luft,Jennifer R Wolfley,Edward H Snell
Joseph R Luft
Observations of crystallization experiments are classified as specific outcomes and integrated through a phase diagram to visualize solubility and thereby direct subsequent experiments. Specific examples are taken from our high-throughput c...
High-Quality Protein Crystal Growth of Mouse Lipocalin-Type Prostaglandin D Synthase in Microgravity [0.03%]
微重力条件下高质量的小鼠白细胞介素型前列腺素D合酶蛋白晶体生长
Koji Inaka,Sachiko Takahashi,Kosuke Aritake et al.
Koji Inaka et al.
Lipocalin-type prostaglandin (PG) D synthase (L-PGDS) catalyzes the isomerization of PGH(2) to PGD(2) and is involved in the regulation of pain and of nonrapid eye movement sleep and the differentiation of male genital organs and adipocytes...
Muhammet Işiklan,Musabbir A Saeed,Avijit Pramanik et al.
Muhammet Işiklan et al.
A thiophene-based tripodal receptor has been synthesized and its complexes with nitrate and iodide have determined by single-crystal X-ray analysis. In the nitrate complex, one nitrate is encapsulated in a selective orientation forming a C(...
Tooth enamel proteins enamelin and amelogenin cooperate to regulate the growth morphology of octacalcium phosphate crystals [0.03%]
牙釉蛋白enamelin和amelogenin通过协作调节八钙磷酸盐晶体生长形态
Mayumi Iijima,Daming Fan,Keith M Bromley et al.
Mayumi Iijima et al.
To examine the hypothetical cooperative role of enamelin and amelogenin in controlling the growth morphology of enamel crystals in the post-secretory stage, we applied a cation selective membrane system for the growth of octacalcium phospha...
Epitaxially Grown Films of Standing and Lying Pentacene Molecules on Cu(110) Surfaces [0.03%]
垂直和卧式pentacene分子在铜(110)表面上的外延生长薄膜
Tatjana Djuric,Thomas Ules,Heinz-Georg Flesch et al.
Tatjana Djuric et al.
This study investigates epitaxially oriented pentacene films grown on Cu(110) surfaces crystallizing either in the "thin film" phase with standing molecules or in the "single crystal" structure with molecules lying with their long axes para...
Solid-State Forms of β-Resorcylic Acid: How Exhaustive Should a Polymorph Screen Be? [0.03%]
β-海因酸固体形式的研究：晶型筛选应该进行到什么程度？
Doris E Braun,Panagiotis G Karamertzanis,Jean-Baptiste Arlin et al.
Doris E Braun et al.
An extensive experimental screen, coupled with a computational study, revealed seven new solid-state forms of β-resorcylic acid. The known, stable polymorph II° shows a reversible phase transformation to the new, kinetically stable, proba...