Polymorphic Protein Crystal Growth: Influence of Hydration and Ions in Glucose Isomerase [0.03%]
多态蛋白质晶体生长：葡萄糖异构酶中水分和离子的影响
C M Gillespie,D Asthagiri,A M Lenhoff
C M Gillespie
Crystal polymorphs of glucose isomerase were examined to characterize the properties and to quantify the energetics of protein crystal growth. Transitions of polymorph stability were measured in poly(ethylene glycol)/NaCl solutions, and one...
Crystal Engineering of l-Alanine with l-Leucine Additive using Metal-Assisted and Microwave-Accelerated Evaporative Crystallization [0.03%]
利用金属辅助及微波加速蒸发结晶法研究l-亮氨酸添加剂对l-丙氨酸晶体工程的影响
Adeolu Mojibola,Gilles Dongmo-Momo,Muzaffer Mohammed et al.
Adeolu Mojibola et al.
In this work, we demonstrated that the change in the morphology of l-alanine crystals can be controlled with the addition of l-leucine using the metal-assisted and microwave accelerated evaporative crystallization (MA-MAEC) technique. Cryst...
Katy N Olafson,Jeffrey D Rimer,Peter G Vekilov
Katy N Olafson
Hematin crystallization is an essential component of the physiology of malaria parasites. Several antimalarial drugs are believed to inhibit crystallization and expose the parasites to toxic soluble hematin. Hence, understanding the mechani...
Crystallizing Membrane Proteins in the Lipidic Mesophase. Experience with Human Prostaglandin E2 Synthase 1 and an Evolving Strategy [0.03%]
液晶相中膜蛋白的结晶：人类前列腺素E2合成酶1的经验与策略初探
Dianfan Li,Nicole Howe,Abhiram Dukkipati et al.
Dianfan Li et al.
The lipidic mesophase or in meso method for crystallizing membrane proteins has several high profile targets to its credit and is growing in popularity. Despite its success, the method is in its infancy as far as rational crystallogenesis i...
Tracking Amorphous Precursor Formation and Transformation during Induction Stages of Nucleation [0.03%]
在形核诱导阶段追踪非晶前驱体的形成和转化
Baoquan Xie,Timothy J Halter,Ballav M Borah et al.
Baoquan Xie et al.
Hydroxyapatite (HAP) participates in vertebral bone and tooth formation by a nonclassical hitherto unknown nucleation mechanism, in which amorphous precursors form and transform during long induction periods. Elucidation of the mechanism by...
Noncentrosymmetric Packings Influenced by Electronic Properties of Products of Click Reactions [0.03%]
受点击反应产物电子性质影响的非中心对称填充
Rebecca C Laird,Nam P Nguyen,Sara F Rusch et al.
Rebecca C Laird et al.
Though 1,4-disubstituted 1,2,3-triazole rings have been utilized as electronic bridges in the solution phase, the use of a triazole ring to serve as an electronic bridge of small molecules in the crystalline state has been underdeveloped. H...
Time-Dependent Solid State Polymorphism of a Series of Donor-Acceptor Dyads [0.03%]
一系列给体-受体二聚体的时依赖固态聚合物异构体现象
Cameron Peebles,Paul M Alvey,Vincent Lynch et al.
Cameron Peebles et al.
In order to exploit the use of favorable electrostatic interactions between aromatic units in directing the assembly of donor-acceptor (D-A) dyads, the present work examines the ability of conjugated aromatic D-A dyads with symmetric side c...
Experimental Electron Density and Neutron Diffraction Studies on the Polymorphs of Sulfathiazole [0.03%]
硫氮苯多型体的实验电子密度和中子衍射研究
Ioana Sovago,Matthias J Gutmann,J Grant Hill et al.
Ioana Sovago et al.
High resolution X-ray diffraction data on forms I-IV of sulfathiazole and neutron diffraction data on forms II-IV have been collected at 100 K and analyzed using the Atoms in Molecules topological approach. The molecular thermal motion as j...
Investigations on the use of graphite electrodes using a Hull-type growth cell for the electrochemically-assisted protein crystallization [0.03%]
利用Hull型生长电池电化学辅助蛋白质结晶对石墨电极的探究
Patricio J Espinoza-Montero,María Esther Moreno-Narváez,Bernardo A Frontana-Uribe et al.
Patricio J Espinoza-Montero et al.
This paper describes the use of an electrochemical Hull type cell adapted for protein crystallization evaluating three inclination angles (45°, 60° and 90°). For optimization experiments, classical platinum wire electrodes were used and ...
Morphologies in Solvent-Annealed Clotrimazole Thin Films Explained by Hansen-Solubility Parameters [0.03%]
溶剂老化克霉唑薄膜的形貌由汉森溶解度参数解释
Heike M A Ehmann,Andreas Zimmer,Eva Roblegg et al.
Heike M A Ehmann et al.
The induction of different crystal morphologies is of crucial importance for many applications. In this work, the preparation of various crystal morphologies within clotrimazole films on glass substrates is demonstrated. Amorphous clotrimaz...