Doris E Braun,Maria Orlova,Ulrich J Griesser
Doris E Braun
Hydrate and anhydrate crystal structure prediction (CSP) of creatine (CTN), a heavily used, badly water soluble, zwitterionic compound, has enabled the finding and characterization of its anhydrate polymorphs, including the thermodynamic ro...
Madhav Sigdel,Marc L Pusey,Ramazan S Aygun
Madhav Sigdel
Thousands of experiments corresponding to different combinations of conditions are set up to determine the relevant conditions for successful protein crystallization. In recent years, high throughput robotic set-ups have been developed to a...
Daniel Jacobsson,Fangfang Yang,Karla Hillerich et al.
Daniel Jacobsson et al.
III-V Nanowires (NWs) grown with metal-organic chemical vapor deposition commonly show a polytypic crystal structure, allowing growth of structures not found in the bulk counterpart. In this paper we studied the radial overgrowth of pure wu...
Control of Assembly of Dihydropyridyl and Pyridyl Molecules via Directed Hydrogen Bonding [0.03%]
通过导向氢键控制二氢吡啶基和吡啶基分子的组装
Jian Lü,Li-Wei Han,Nada H Alsmail et al.
Jian Lü et al.
The crystallization of two dihydropyridyl molecules, 1,4-bis(4-(3,5-dicyano-2,6-dipyridyl)dihydropyridyl)benzene ([C40H24N10]·2DMF, 1·2DMF; DMF = dimethylformamide) and 1,4-bis(4-(3,5-dicyano-2,6-dipyridyl)dihydropyridyl)phenylbenzene ([C...
Solid-State Examination of Conformationally Diverse Sulfonamide Receptors Based on Bis(2-anilinoethynyl)pyridine, -Bipyridine, and -Thiophene [0.03%]
基于双（2-芳基乙炔基）吡啶、-联吡啶和-并噻吩的磺酰胺受体的固态构象研究
Orion B Berryman,Charles A Johnson nd,Chris L Vonnegut et al.
Orion B Berryman et al.
Utilizing an induced-fit model and taking advantage of rotatable acetylenic C(sp)-C(sp2) bonds, we disclose the synthesis and solid-state structures of a series of conformationally diverse bis-sulfonamide arylethynyl receptors using either ...
Surface-Induced Polymorphism as a Tool for Enhanced Dissolution: The Example of Phenytoin [0.03%]
表面诱导多形性作为增强溶解的一种工具——以苯妥英为例
Daniela Reischl,Christian Röthel,Paul Christian et al.
Daniela Reischl et al.
Polymorphism and morphology can represent key factors tremendously limiting the bioavailability of active pharmaceutical ingredients (API), in particular, due to solubility issues. Within this work, the generation of a yet unknown surface-i...
Christian Röthel,Michal Radziown,Roland Resel et al.
Christian Röthel et al.
Defined fabrication of organic thin films is highly desired in technological, as well as pharmaceutical, applications since morphology and crystal structure are directly linked to physical, electrical, and optical properties. Within this wo...
Effect of the Materials Properties of Hydroxyapatite Nanoparticles on Fibronectin Deposition and Conformation [0.03%]
羟基磷灰石纳米粒子材料属性对层粘连蛋白吸附量及构象的影响研究
Fei Wu,Debra D W Lin,Jin Ho Chang et al.
Fei Wu et al.
Hydroxyapatite (HAP, Ca10(PO4)6(OH)2) nanoparticles with controlled materials properties have been synthesized through a two-step hydrothermal aging method to investigate fibronectin (Fn) adsorption. Two distinct populations of HAP nanopart...
Hirshfeld Surface Investigation of Structure-Directing Interactions within Dipicolinic Acid Derivatives [0.03%]
二乙酸二氨基己二酸衍生物中的结构导向相互作用的Hirshfeld面研究
Adam D Martin,Joshua Britton,Timothy L Easun et al.
Adam D Martin et al.
Six compounds based on dipicolinic acid esters have been synthesized and Hirshfeld surfaces used to investigate the structure-directing effects of functional groups in controlling their solid-state behavior. Compounds 1-4 are 4-bromo dipico...
Peter Neugebauer,Johannes G Khinast
Peter Neugebauer
Protein crystals have many important applications in many fields, including pharmaceutics. Being more stable than other formulations, and having a high degree of purity and bioavailability, they are especially promising in the area of drug ...