MC-LR induced apoptosis in human embryonic kidney (HEK293) cells through activation of TNF-R1/RIPK1 pathway [0.03%]
MC-LR通过激活TNF-R1/RIPK1途径诱导人类肾胚细胞凋亡
Yaqi Wang,Yue Yang,Mei Yuan et al.
Yaqi Wang et al.
In recent years, the outbreak of cyanobacterial blooms has become increasingly frequent. Microcystin-LR (MC-LR), a metabolite of cyanobacteria, poses a significant threat to the ecosystem and human health. Several studies have demonstrated ...
Cocoa (Theobroma cacao L.) photobiological effect on human fibroblast cells (HFF-1) exposed to ultraviolet B (UVB) radiation [0.03%]
cocoa（Theobroma cacao L.）对紫外线B（UVB）辐射暴露的人成纤维细胞系HFF-1的光生物学效应
Josiéle da Silva Prade,Camila Medianeira da Silva D&#x;Ávila,Thayline Correia da Silva et al.
Josiéle da Silva Prade et al.
This study aimed to investigate the in vitro photobiological action of cocoa solution on a human fibroblast cell line (HFF-1) exposed to ultraviolet B (UVB) radiation. Three experimental models were utilized, where fibroblast cells were tre...
Effect of 2,5-hexanedione on rat ovarian granulosa cell apoptosis involves endoplasmic reticulum stress-dependent m-TOR signaling pathway [0.03%]
己二酮诱导大鼠卵巢颗粒细胞凋亡涉及内质网应激介导的mTOR信号通路
Lemei Zhu,Yue Yang,Jingsi Tan et al.
Lemei Zhu et al.
Occupational exposure to N-hexane/2,5-hexanedione (2,5-HD) was found to adversely affect reproductive functions in females. However, there are few studies regarding the mechanisms underlying reproductive system damage initiated by 2,5-HD. S...
Effect of chronic low-dose microcystin-LR exposure on jejunum apoptosis via RAF/ERK signaling pathway in mouse [0.03%]
微囊藻毒素-LR慢性低剂量暴露对小鼠回肠RAF/ERK信号途径调控的肠隐窝细胞凋亡的影响效应研究
Sihong Long,Cong Wen,Wen Zeng et al.
Sihong Long et al.
Microcystin-LR (MC-LR), a class of cyclic heptapeptide compounds synthesized by cyanobacterial species, presents a significant risk to ecological systems and public health. Exposure to MC-LR was found to induce damage to various organs. One...
Element contents in edible seaweeds and assessment of human health from their consumption [0.03%]
可食用海藻中的元素含量及其对人体健康的影响评估
Caroline Rodrigues Albuquerque,Paulo Sergio Cardoso da Silva,Fungyi Chow et al.
Caroline Rodrigues Albuquerque et al.
Seaweed, traditionally part of the daily diet of Asian countries, has become a common dish in Western countries. In Brazil, although contributing to lesser amounts, seaweed consumption has been incorporated into the population eating habits...
Cytotoxic effects of the standardized extract from Curcuma aromatica Salisb. rhizomes via induction of mitochondria-mediated caspase-dependent apoptotic pathway and p21-mediated G0/G1 cell cycle arrest on human gastric cancer AGS cells [0.03%]
姜黄根茎提取物通过线粒体介导的半胱天冬酶依赖性凋亡途径和P21介导的G0 / G1期细胞周期停滞在人胃癌AGS细胞中产生细胞毒性作用
Chinh Chung Doan,Thanh Long Le,Nguyen Quynh Chi Ho et al.
Chinh Chung Doan et al.
Curcuma aromatica Salisb. (C. aromatica) is one of the traditional herbs used to treat microbial infection, skin eruption, coronary heart disease, and other diseases, including cancer. However, the inhibitory effects and underlying mechanis...
Association of ambient particulate matter (PM2.5) with reduced sex ratio at birth after the implementation of a rapid transit system in Taipei, Taiwan [0.03%]
快速交通系统实施后台湾台北地区出生性别比与空气悬浮颗粒物（PM2.5）的关系研究
Shang-Shyue Tsai,Yi-Hao Weng,Chun-Yuh Yang
Shang-Shyue Tsai
Sex ratio at birth (SRB) is a simple, noninvasive way to monitor the reproductive health of a population. Apparently only a few studies have assessed the relationship between ambient air pollution and SRBs. The studies that investigated thi...
Allelopathic activity of coffee extracts: implications for germination and initial growth in select weeds and polyploidy in Lactuca sativa L [0.03%]
咖啡提取物的化感作用：对某些杂草发芽和初始生长以及 lettuce 多倍体的影响
Sttela Dellyzete Veiga Franco da Rosa,Ana Luiza de Oliveira Vilela,Marcus Vinicius Prado Alves et al.
Sttela Dellyzete Veiga Franco da Rosa et al.
Coffee beans contain compounds with allelopathic activity, such that some beans that do not meet quality standards might rather be used to obtain a natural herbicide which consequently might be employed to control undesired plants and avoid...
Evaluation of safety and efficacy of Brazilian brown propolis from Araucaria sp. in preventing colon cancer [0.03%]
评估巴西ARAUCARIA种巴西紫丁香树脂蜂胶预防结肠癌的安全性和有效性
Karoline Soares de Freitas,Iara Silva Squarisi,Letícia Teixeira Marcos de Souza et al.
Karoline Soares de Freitas et al.
Brazilian propolis produced by honeybees have been widely studied, but few data exist regarding the safety and pharmacological potential of this natural product. The aim of the present study was to examine the toxicity, genotoxicity, and ch...
cGAS/STING pathway modulation in polyhexamethyleneguanidine phosphate-induced immune dysregulation and pulmonary fibrosis using human monocytic cells (THP-1) and male C57BL/6 mice [0.03%]
聚六亚甲基胍磷酸诱导的免疫失调和肺纤维化中cGAS/STING途径的调节：人单核细胞系（THP-1）及雄性C57BL/6小鼠模型研究
Jin Kyung Seok,Jung In Jee,Minwoo Jeon et al.
Jin Kyung Seok et al.
Polyhexamethyleneguanidine phosphate (PHMG), a widely used antimicrobial agent, has been implicated in humidifier disinfectant-associated lung injuries (HDLI). PHMG exposure suppressed interferon regulatory factor 3 (IRF3) activation and in...