Chemical composition, in vitro and in silico activity of the methanolic extract derived from Vassobia breviflora against clinically relevant bacteria [0.03%]
短花乌头甲醇提取物的化学成分及其体外和分子对接模拟对抗临床相关细菌的作用研究
Altevir Rossato Viana,Erdi Can Aytar,Nickolas Pippi et al.
Altevir Rossato Viana et al.
This study aimed to identify chemical compounds derived from Vassobia breviflora methanolic extract using ESI-ToF-MS and their antioxidant potential activity utilizing the following methods: total phenols, DPPH, and ABTS•+. The MTT assay m...
Contamination levels and distribution of persistent and non-persistent pollutants in paired hair, urine and serum samples from a Belgian non-occupationally exposed population [0.03%]
比利时非职业接触人群中头发、尿液和血清中持久性和非持久性污染物的污染水平及分布状况
Julien Claessens,Patrice Dufour,Nadia Dardenne et al.
Julien Claessens et al.
Designing ideal human biomonitoring studies involves the selection of reliable markers of exposure in adequate biological matrix. Besides conventional matrices such as blood or urine, hair has been increasingly investigated as a promising n...
Buthionine sulfoximine acts synergistically with doxorubicin as a sensitizer molecule on different tumor cell lines [0.03%]
硫氧还蛋白抑制剂布西硫明与阿霉素协同作用促进不同肿瘤细胞系的凋亡
Joedna Cavalcante Pereira,Rayran Walter Ramos de Sousa,Micaely Lorrana Pereira Conceição et al.
Joedna Cavalcante Pereira et al.
The chemotherapeutic drug doxorubicin (DOX) has been widely used for treating solid tumors attributed to its antiproliferative effectiveness; however, its clinical use is limited due to side effects, including cardiotoxicity, myelosuppressi...
Larissa Vivan Cestonaro,Aline Mocellin Conte,Fernanda Capitanio Goldoni et al.
Larissa Vivan Cestonaro et al.
Weeds are a concern in agriculture and the use of herbicides constitutes an effective, efficient, and economical way to control their growth. Recent discoveries of herbicides are promising for the management of resistant weeds. However, the...
Chronic exposure to low-dose MC-LR induces ileal inflammation in mice through the PI3K/AKT/mTOR pathway [0.03%]
微囊藻毒素-LR慢性低剂量暴露通过PI3K/AKT/mTOR信号通路诱导小鼠回肠炎
Mingjie Yang,Shuilin Zheng,Wen Zeng et al.
Mingjie Yang et al.
The global phenomenon of cyanobacterial bloom pollution is spreading globally due to climate change and eutrophication. It is well established that harmful cyanobacteria produce a wide range of toxins including microcystin-LR (MC-LR), a cyc...
Microcystin-LR induces lung injury in mice through the NF-κB/NLRP3 pathway [0.03%]
微囊藻毒素-LR通过NF-κB/NLRP3途径诱导小鼠肺损伤
Yin Zhang,Ying Guan,Manni Dai et al.
Yin Zhang et al.
Microcystin-LR (MC-LR) a cyclic toxin produced by cyanobacterial species is known to exert detrimental effects on various organs, including lung. Several investigators demonstrated that MC-LR exerts pulmonary toxicity, but the underlying me...
Toxic effects of tetracycline on non-target lichen Evernia prunastri [0.03%]
四环素对非靶向地衣Evernia prunastri的毒性效应
Gintarė Sujetovienė,Martynas Jasas,Diana Miškelytė et al.
Gintarė Sujetovienė et al.
Tetracycline (TC) antibiotics are one of the class of drugs widely used in clinical practice but also constitute a significant environmental concern. However, the adverse effects of TC on non-target organisms have not been well studied. The...
Raquel Stefanello,Raissa Tainá Puntel,Daiane Balconi Bevilaqua et al.
Raquel Stefanello et al.
Rice is considered to be moderately salt-tolerant during germination, development, and ripening stages, and environmentally sensitive during seedling and reproductive stages, which affects seedling emergence and growth, resulting in signifi...
Penilumamide, a novel SIRT1 activator, protects UVB-induced photodamages in HaCaT cells [0.03%]
新型SIRT1激活剂Penilumamide保护HaCaT细胞免受UVB诱导的光损伤
Ji Won Park,Jae Hyeon Park,Haeun Lee et al.
Ji Won Park et al.
Ultraviolet-B (UVB) radiation is a major physical factor that induces structural changes in human skin. The aim of this study was to determine whether the novel silent information regulator 1 (sirtuin 1 SIRT1) protein activator, penilumamid...
Exposure to MC-LR activates the RAF/ERK signaling pathway, leading to renal inflammation and tissue damage in mice [0.03%]
微囊藻毒素-LR通过活化RAF/ERK信号通路诱导小鼠肾组织炎症及损伤反应
Yiwen Hou,Ying Liu,Yue Yang et al.
Yiwen Hou et al.
Exposure to microcysatin-LR (MC-LR) is known to result in kidney damage, however the underlying mechanisms involved in MC-LR-initiated renal injury are not known. Thus, the aim of this study was to examine the effects of exposure to MC-LR o...