Integrating ADMET, enrichment analysis, and molecular docking approach to elucidate the mechanism of Artemisia herba alba for the treatment of inflammatory bowel disease-associated arthritis [0.03%]
基于ADMET、富集分析及分子对接的阿博艾虎耳草治疗溃疡性结肠炎关节炎作用机制研究
Hicham Wahnou,Fouzia Hmimid,Ahmed Errami et al.
Hicham Wahnou et al.
Inflammatory Bowel Disease-Associated Arthritis (IBD-associated arthritis) poses a significant challenge, intertwining the complexities of both inflammatory bowel disease (IBD) and arthritis, significantly compromising patient quality of li...
Chemical composition, cytotoxicity, antimicrobial, antibiofilm, and anti-quorum sensing potential of Mentha Piperita essential oil against the oral pathogen Streptococcus mutans [0.03%]
薄荷油的化学成分、细胞毒性以及对口腔病原菌变异链球菌的抑菌、杀菌和抑制群体感应作用
Leonardo Quintana Soares Lopes,Pedro Henrique Fortes Guerim,Maria Eduarda Maldonado et al.
Leonardo Quintana Soares Lopes et al.
Dental caries is a highly prevalent oral disease affecting billions of individuals globally. The disease occurs chemically as a result of breakdown of the tooth surface attributed to metabolic activity in colonizing biofilm. Biofilms, compo...
A rapid spectrophotometric test for assessing skin sensitization potential of chemicals by using N-acetyl-L-cysteine methyl ester in chemico [0.03%]
一种快速光谱法化学测试：使用N-乙酰半胱氨酸甲酯评估化学品致皮肤过敏性潜在风险
Rahul Upadhyay Nepal,Tae Cheon Jeong
Rahul Upadhyay Nepal
During the key event 1 of skin sensitization defined as covalent binding or haptenization of sensitizer to either thiol or amino group of skin proteins, a sensitizer not only covalently binds with skin proteins but also interacts with nucle...
Kirsten Earl,Harriet Sleight,Nahum Ashfield et al.
Kirsten Earl et al.
The application of biosolids, manure, and slurry onto agricultural soils and the growing use of treated wastewater in agriculture result in the introduction of human and veterinary pharmaceuticals to the environment. Once in the soil enviro...
Enhancement of keratinocyte survival and migration elicited by interleukin 24 upregulation in dermal microvascular endothelium upon welding-fume exposure [0.03%]
焊接烟雾暴露时真皮微血管内皮细胞源性干扰素λ1的上调促进角质形成细胞存活和迁移
Maori Kono,Nami Ishihara,Tatsuto Nakane et al.
Maori Kono et al.
Occupational exposure to welding fumes constitutes a serious health concern. Although the effects of fumes on the respiratory tract have been investigated, few apparent reports were published on their effects on the skin. The purpose of thi...
Air pollution and incident sarcoidosis in central Pennsylvania [0.03%]
pennsylvania中心地区的空气污染与新发维姆病的关系
Jeff D Yanosky,Abigail Washington,Galen T Foulke et al.
Jeff D Yanosky et al.
Sarcoidosis is a chronic granulomatous disease predominantly affecting the lungs and inducing significant morbidity and elevated mortality rate. The etiology of the disease is unknown but may involve exposure to an antigenic agent and subse...
Evaluation of infliximab-induced genotoxicity and possible action on BCL-2 and P53 genes [0.03%]
评估英夫利昔诱导的基因毒性及其对BCL-2和P53基因的作用可能性
Murillo de Sousa Pinto,Luiz Guilherme Oliveira Fontoura,Isabela da Rosa Borges et al.
Murillo de Sousa Pinto et al.
Although the last pandemic created an urgency for development of vaccines, there was a continuous and concerted effort to search for therapeutic medications among existing drugs with different indications. One of the medications of interest...
Toxicological assessment of the Achyrocline satureioides aqueous extract in the Caenorhabditis elegans alternative model [0.03%]
基于Caenorhabditis elegans的替代模型对Achyrocline satureioides水提物的毒理学评估
Péterson Alves Santos,Mariana Uczay,Pricila Pflüger et al.
Péterson Alves Santos et al.
Achyrocline satureioides, popularly called "marcela" in Brazil, is used in traditional medicine in South America. A. satureioides, inflorescences are used for many conditions, including to minimize the Sars-Cov-2 symptoms. Therefore, the ai...
Effects of a S-metolachlor based herbicide on two plant models: Zea mays L. and Lactuca sativa L [0.03%]
S-甲基氯代乙酸盐除草剂对两种植物模式生物的影响：Zea mays L.和Lactuca sativa L.
Quenia Maria Silva,Marcel José Palmieri,Larissa Fonseca Andrade-Vieira
Quenia Maria Silva
Corn is the second most cultivated crop in Brazil, the number-one country in pesticide consumption. Chemical control of weeds is performed using herbicides such as S-metolachlor with pre- and post-emergence action and thus the toxicity of h...
Physiological and toxicological response of Microcystis aeruginosa BCCUSP232 exposed to Salvinia auriculata extracts [0.03%]
水鳖提取物对铜绿微囊藻的生理及毒性效应研究
Regildo Márcio Gonçalves da Silva,Anderson Lourenção,Gustavo Franciscatti Mecina et al.
Regildo Márcio Gonçalves da Silva et al.
Microcystis aeruginosa is one of the most predominant freshwater bloom-forming cyanobacterium found globally which is capable of producing toxic secondary metabolites including microcystins that might intoxicate animals and humans when cont...