Is Site of Radiation Therapy Associated With Pathologic Complete Response in Patients With Locally Advanced Esophageal Cancer? [0.03%]
放疗部位与局部晚期食管癌患者的病理完全缓解相关吗？
Pranit Singh,Sylvia Choo,Jacob Adams et al.
Pranit Singh et al.
IntroductionNeoadjuvant chemoradiation (CRT) is commonly used for esophageal cancer (EC), with pathologic complete response (pCR) linked to improved prognosis. pCR rates range from 25%-30% for adenocarcinoma to 50% for squamous cell carcino...
Cancer Stem Cells Decide the Fate of Cancer Immunotherapy by Remodeling Tumor Microenvironment [0.03%]
肿瘤微环境重塑决定癌症免疫治疗命运的癌症干细胞研究进展
Sourio Chakraborty,Udit Basak,Sumon Mukherjee et al.
Sourio Chakraborty et al.
Success of cancer immunotherapy (CIT) is intricately influenced by the tumor microenvironment (TME), a complex ecosystem that encompasses immune cells, stromal elements, and extracellular components. Despite the clinical breakthroughs of im...
A New Era in Oncology: Clinical Insights Into the Application of Oncolytic Viruses [0.03%]
肿瘤学的新时代：溶瘤病毒应用的临床见解
S M Shahriar Alam,Mashiat Tasnim,Tasbir Amin et al.
S M Shahriar Alam et al.
When considering treatment-related side effects, cancer therapies often present the most significant severity. Given considerations of safety and efficacy, there is a growing inclination towards biological therapeutic approaches, with Oncol...
A Preliminary Prospective Study on the Association of Polymorphisms in BDNF, ARRB2 and KCNJ6 and Response to Fentanyl for Pain Management in Advanced Cancer [0.03%]
一项初步的前瞻性的研究：脑源性神经营养因子、芳烃受体拮抗剂2型和钾通道依赖鸟苷酸调节因子六型多态性与癌痛患者对喷他那リン镇痛效应关联性分析
John Prenzler,Alison Haywood,Heidi Sutherland G et al.
John Prenzler et al.
IntroductionPain is common in cancer patients, particularly in the advanced stage of the disease with more than 70% prevalence. Despite research regarding cancer pain management, clinicians' ability to predict and manage patient pain remain...
Adverse Events of Immune Checkpoint Inhibitors in Cancer Patients with Comorbid Diabetes: A Real-World Pharmacovigilance Analysis of the FDA Adverse Event Reporting System Database (2011-2025) [0.03%]
免疫检查点抑制剂在伴有糖尿病的癌症患者中的不良事件：对FDA不良事件报告系统数据库（2011-2025）的真实世界药物流行病学分析
Minxia Yang,Di Qiu,Minguang Huang et al.
Minxia Yang et al.
IntroductionImmune checkpoint inhibitors (ICIs) have redefined cancer therapeutics. However, they may provoke immune-related adverse events (irAEs), with diabetes potentially altering their patterns. We aimed to investigate whether diabetic...
Bruno Muñante,Roberto Paz-Manrique,Joseph A Pinto et al.
Bruno Muñante et al.
BackgroundBreast cancer remains a leading cause of cancer-related morbidity and mortality globally, with BRCA1/2 mutation carriers facing distinct challenges due to aggressive tumor biology and heightened risks of contralateral and secondar...
Development and Validation of a Nomogram for Predicting Specific Mortality Risk After Surgery for Locally Advanced Rectal Cancer: Studies Based on SEER Database and External Validation Cohorts [0.03%]
基于SEER数据库和外部验证队列的局部晚期直肠癌术后专属性死亡风险预测列线图的建立及验证研究
Shufa Tan,Shuang Liu,Yunyi Yang et al.
Shufa Tan et al.
IntroductionRectal cancer, characterized by a high global incidence rate, is a significant malignancy. This study aimed to develop a competing risk model utilizing the SEER database to estimate the risk of cancer-specific mortality in patie...
Prognostic Value of Handgrip Strength in Lung Cancer: Findings From a Multicenter Prospective Cohort Study [0.03%]
一项多中心前瞻性队列研究中肺癌患者手握力的预后价值
Xin Wang,Hong Zhao,Lu Liang et al.
Xin Wang et al.
BackgroundHandgrip strength (HGS), a simple and practical indicator of skeletal muscle function, has emerged as a potential prognostic marker, yet its predictive value in lung cancer remains to be fully elucidated. This study aimed to evalu...
Assessment of the Quality of Cervical Cancer Prevention Services in Southwest Nigeria: A Cross-Sectional Study Using Donabedian's Quality Framework [0.03%]
尼日利亚西南部宫颈癌防治服务的质量评估：一项基于Donabedian质量框架的横断面研究
Esther Kikelomo Afolabi,Adenike Ayobola Eunice Olaogun
Esther Kikelomo Afolabi
IntroductionCervical Cancer (CC) is the second leading cause of cancer-related deaths among women in Nigeria, after breast cancer. However, there is a significant gap in evaluating prevention services due to the absence of organized and sus...
Feasibility and Acceptability of an App-Based, Multimodal Prehabilitation Program for Women Undergoing Surgery for Gynaecological Cancer [0.03%]
基于应用程序的多模式围术期康复计划在妇科癌症手术患者中可行性与接受度的研究
Chhaya Ganda-Heath,Anke Smits,Christine Ang et al.
Chhaya Ganda-Heath et al.
IntroductionPrehabilitation aims to optimise functional capacity, nutritional status, and mental wellbeing, to minimise surgical morbidity and enhance recovery. Hospital-based prehabilitation programs may face practical barriers, such as di...