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期刊名:Journal of clinical hypertension

缩写:J CLIN HYPERTENS

ISSN:1524-6175

e-ISSN:1751-7176

IF/分区:2.5/Q2

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Clinical Trial Case Reports Meta-Analysis RCT Review Systematic Review
Classical Article Case Reports Clinical Study Clinical Trial Clinical Trial Protocol Comment Comparative Study Editorial Guideline Letter Meta-Analysis Multicenter Study Observational Study Randomized Controlled Trial Review Systematic Review
Leopoldo Raij Leopoldo Raij
Endothelial dysfunction is characterized by a vasoconstrictive and prothrombotic state in the vasculature; it plays a role in all stages of cardiac disease and is a significant independent predictor of cardiovascular outcomes. Nitric oxide ...
Matthias Hermann,Andreas Flammer,Thomas F Lüscher Matthias Hermann
Hypertension is a major risk factor for cardiovascular disease, and reduction of elevated blood pressure significantly reduces the risk of cardiovascular events. Endothelial dysfunction, which is characterized by impairment of nitric oxide ...
Thomas D Giles Thomas D Giles
Nitric oxide (nitrogen monoxide) (NO) plays an important role in a wide range of physiologic processes. A major mediator of endothelial function, NO regulates vasodilatory and antithrombotic actions in the vasculature and plays a role in re...
Leoní Adriana Souza-Barbosa,Sílvia E Ferreira-Melo,Samira Ubaid-Girioli et al. Leoní Adriana Souza-Barbosa et al.
It is unclear whether single and combined pharmacologic inhibition of the renin-angiotensin-aldosterone system have similar effects on endothelial function and blood pressure (BP). The authors evaluated 63 hypertensive patients divided into...
Dimitris P Papadopoulos,Thomas K Makris,Maria Poulakou et al. Dimitris P Papadopoulos et al.
Essential hypertension is associated with increased plasma leptin levels and decreased human soluble leptin receptor (hsLR) concentration. The aim of this study was to determine whether the concentration of hsLR differs among offspring of h...
Annaswamy Raji,Jonathan S Williams,Paul N Hopkins et al. Annaswamy Raji et al.
The authors assessed the familial aggregation of cardiometabolic abnormalities (elevated homeostasis model assessment [HOMA], triglycerides [TG], and low-density lipoprotein [LDL] and reduced high-density lipoprotein [HDL]) among hypertensi...
Sanjay Rajagopalan,Mbabazi Kariisa,Santo Dellegrottaglie et al. Sanjay Rajagopalan et al.
The renin-angiotensin system (RAS) may play a role in vascular aging. The authors hypothesized that blockade of the angiotensin II type 1 receptor with an angiotensin receptor blocker in healthy elderly subjects improves vascular compliance...
Joel J Pins,Joseph M Keenan Joel J Pins
Previous studies have shown that peptides derived from milk proteins can improve blood pressure. Therefore, the authors tested the blood pressure-lowering effects of a hydrolyzed whey protein supplement rich in bioactive peptides. In a 6-we...