Intracranial Progression-Free Survival Correlates with Overall Survival and Varies by Tumor Subtype in Patients with Breast Cancer and Brain Metastases [0.03%]
乳腺癌脑转移患者中,无进展生存期与总生存期相关且不同肿瘤亚型存在差异
Sarah L Sammons,Ryan Shanley,Carey K Anders et al.
Sarah L Sammons et al.
Background: Brain metastases in patients with breast cancer (BCBM) are common. While the Breast Graded Prognostic Assessment (Breast GPA) predicts overall survival (OS), its ability to predict intracranial progression-fre...
Corrigendum to: Single-cell profiling of peripheral and local immune compartments reveal unique genotype-independent prognostic immune signatures across isocitrate dehydrogenase-stratified glioma [0.03%]
对胶质瘤中异柠檬酸脱氢酶分层的外周和局部免疫隔室进行单细胞谱型分析可揭示独特的基因型独立的预后免疫标志物校正意见
Published Erratum
Neuro-oncology. 2026 May 9:noag092. DOI:10.1093/neuonc/noag092 2026
Corrigendum to: G-quadruplex stabilizer CX-5461 effectively combines with radiotherapy to target α-thalassemia/mental retardation X-linked-deficient malignant glioma [0.03%]
CX-5461与放疗有效结合靶向α-地中海贫血/性连锁精神发育迟滞综合征缺陷的恶性胶质瘤的校正说明文:G-四链体稳定剂
Published Erratum
Neuro-oncology. 2026 May 9:noag089. DOI:10.1093/neuonc/noag089 2026
Association between radiographic response and subsequent recurrence in brain metastases treated with radiation: implications for response assessment criteria [0.03%]
放射治疗后脑转移瘤影像学反应与后续复发之间的关系:对疗效评价标准的启示
Benjamin Grobman,Nayan Lamba,Sandeep Purohit et al.
Benjamin Grobman et al.
Background: The Response Assessment in Neuro-Oncology Brain Metastasis (RANO-BM) criteria comprise the foundation for assessment of investigational approaches in brain metastases, including novel radiation-based technique...
Discrepancies in Inter-Rater Agreement on Resectability of Recurrent Glioblastoma: Complementary Post-hoc Analysis of the Prospective, Randomized DIRECTOR Trial [0.03%]
关于复发性胶质母细胞瘤切除范围的评定者一致性差异:前瞻性、随机DIRECTOR试验的事后分析补充研究
Philipp Karschnia,Nico Teske,Emilie Le Rhun et al.
Philipp Karschnia et al.
Background: Tumor resection is a prerequisite in many studies of new glioblastoma therapeutics; however, no clear parameters for "resectability" exist. We evaluated inter-rater variability in assessing tumor resectability...
Automatic Extraction of PET RANO Criteria with an Externally Validated Deep Learning Model: Application to [18F]FDOPA PET Imaging [0.03%]
基于外部验证的深度学习模型自动提取PET-RANO标准及其在[18F]FDOPA-PET成像中的应用
Timothée Zaragori,Laura Rozenblum,Guido Rovera et al.
Timothée Zaragori et al.
Background: Automatic segmentation of gliomas on amino acid PET is essential for quantitative tumor assessment, a pillar in monitoring gliomas under treatment. This study aimed to develop a deep learning model for the aut...
Molecular modulators of CDK4/6 inhibitor response in experimental glioma identified through genome-wide CRISPR-Cas9 screening [0.03%]
通过全基因组CRISPR-Cas9筛选鉴定出的实验性胶质瘤中针对CDK4/6抑制剂反应的分子调节因子
Surender Surender,Lara Annina Haeusser,Laurence Kuhlburger et al.
Surender Surender et al.
Background: Glioblastoma harbors frequent alterations in the retinoblastoma (RB1) pathway, providing a genetic rationale for therapeutic targeting with cyclin-dependent kinase 4/6 (CDK4/6) inhibitors. The NOA-20 trial did...
Phase separation of TRNAU1AP protein sustains selenoprotein translation and promotes glioblastoma tumorigenesis [0.03%]
TRNAU1AP蛋白的相分离利于硒蛋白合成并促进胶质母细胞瘤发生发展
Xiaowei Zhang,Li Li,Linlin Li et al.
Xiaowei Zhang et al.
Background: Glioblastoma (GBM) depends on selenoproteins, yet the mechanisms underlying their dysregulation remain poorly understood. The tRNA-binding protein TRNAU1AP also remains largely uncharacterized, with its mechan...
A comprehensive clinical, molecular, radiological, and surgical analysis for predicting prognosis in IDH-mutant astrocytoma patients [0.03%]
全面的临床、分子、影像学和手术分析可预测IDH突变型胶质瘤患者的预后
Minjee Cho,Minjin Kim,Hyeonjin Kim et al.
Minjee Cho et al.
Background: To comprehensively investigate clinical, molecular, radiological, and surgical factors for prediction of progression-free survival (PFS) in patients with isocitrate dehydrogenase (IDH)-mutant astrocytomas. ...