Health-related quality of life and cognition in long-term oligodendroglioma survivors: A landmark study [0.03%]
长期少突胶质细胞瘤幸存者的生命质量和认知功能：一项里程碑式的研究
Martin J van den Bent
Martin J van den Bent
Cysteine addiction in drug resistant glioblastoma and therapeutic targeting with designer selenium compounds [0.03%]
用设计型硒化合物治疗耐药胶质母细胞瘤半胱氨酸成瘾性研究
Deanna Tiek,Xiao Song,Runxin Wu et al.
Deanna Tiek et al.
Background: Cysteine is a multifunctional amino acid that can be oxidized affecting disulfide bond formation, redox signaling, and protein function. Reactive oxygen species (ROS) and the metabolic environment dictate cyst...
Bayesian Adaptive Randomized Trial of Blended Cognitive Behavioral Therapy for Severe Fatigue in Stable Diffuse Glioma [0.03%]
胶质瘤伴严重疲劳的认知行为疗法的适应性随机试验
Maxine Gorter,Jantine G Röttgering,Vera Belgers et al.
Maxine Gorter et al.
Background: While severe fatigue is common in patients with diffuse glioma, no evidence-based treatment is currently available. The objective of this RCT was to evaluate efficacy of blended cognitive behavioral therapy (b...
Seeing the Whole Picture: AI Aids Integrative Diagnosis of Gliomas from Histopathology [0.03%]
从组织病理学整合诊断胶质瘤的全图：人工智能助力看见全图式诊断胶质瘤
Xiufang Ren,Wen Cheng,Anhua Wu
Xiufang Ren
Reliable cognitive changes the first year following guideline-based treatment of IDH mutated gliomas: a longitudinal multicenter study [0.03%]
异柠檬酸脱氢酶突变型胶质瘤指南化治疗后第一年的可靠认知变化：一项多中心纵向研究
Isabelle Rydén,Francesco Latini,Åsa Alberius Munkhammar et al.
Isabelle Rydén et al.
Background: Management of isocitrate dehydrogenase (IDH) mutated gliomas is multidisciplinary and current guidelines support early multimodal treatment. The effects of this treatment approach on cognition are less studied...
Phase II study of safusidenib erbumine in patients with chemotherapy- and radiotherapy-naïve isocitrate dehydrogenase 1-mutated WHO grade 2 gliomas [0.03%]
新诊断的IDH1突变型WHO 2级胶质瘤患者接受SAFUSENIB ERBUMINE治疗的II期研究
Yoshiki Arakawa,Ryuta Saito,Yonehiro Kanemura et al.
Yoshiki Arakawa et al.
Background: Gliomas are primary brain tumors arising from glial cells. WHO grade 2 gliomas are initially managed with surgery for diagnosis and tumor reduction. However, complete resection is difficult due to their infilt...
Single nucleus transcriptomics, pharmacokinetics, and pharmacodynamics of CDK4/6 and mTOR inhibition in a phase 0/1 trial of recurrent high-grade glioma [0.03%]
单核转录组学、药代动力学和药效学：CDK4/6和mTOR抑制在复发性高级别胶质瘤一期试验中的作用
Kevin C Johnson,An-Chi Tien,Jun Jiang et al.
Kevin C Johnson et al.
Background: Outcomes for adult patients with high-grade glioma (HGG) remain poor, necessitating new treatment strategies. Key challenges include poor drug penetration in the brain and malignant cell state plasticity. Phas...
A Systematic Study of Molecular Diagnosis, Treatment and Prognosis in Infant-Type Hemispheric Glioma): An Individual Patient Data Meta-analysis of 164 patients [0.03%]
婴幼儿半球胶质瘤分子诊断、治疗和预后系统研究（基于164例患者个体级别数据的meta分析）
Lara Chavaz,Aditi Bagchi,Sandeep K Dhanda et al.
Lara Chavaz et al.
Background: Due to the novelty and rarity of infant-type hemispheric glioma (IHG), optimal treatment and factors determining clinical outcomes are yet to be established. ...
Assessment of Molecular Tools in Pediatric, Adolescent and Young Adult Meningioma Highlights the Need for Lifespan Precision in Neuro-Oncology [0.03%]
分子工具在儿科、青少年和年轻成人脑膜瘤中的评估强调了神经肿瘤学中生命周期精确诊断的必要性
Leeor S Yefet,Alexander P Landry,Justin Z Wang et al.
Leeor S Yefet et al.
Background: Adolescent and young adult (AYA) patients remain underrepresented in neuro-oncology research. Despite being the second most common primary brain tumor in this population, meningiomas have not been studied usin...
Reflecting on Scientific Growth and Innovation as the Society for Neuro-Oncology Turns 30 [0.03%]
神经肿瘤学学会三十周年之际对科学进步与创新的反思
Macarena I De La Fuente,Priscilla K Brastianos,Bradley Gampel et al.
Macarena I De La Fuente et al.
The Society for Neuro-Oncology (SNO) marks its 30th anniversary in 2025, providing an opportunity to reflect on scientific advances and future directions on the field. Over three decades, SNO has catalyzed scientific innovation, education, ...