Correction to "Hypertonic saccharide solution delays pyroptosis in murine macrophages regardless of the membrane binding of gasdermin D N-terminal" [0.03%]
“高渗糖溶液可抑制小胶质细胞pyroptosis且与Gasdermin D的N端膜结合无关”的勘误通知
Jianan Ren
Jianan Ren
Published Erratum
European journal of immunology. 2025 Nov;55(11):e70089. DOI:10.1002/eji.70089 2025
Kahkashan Kamal,James Trumbo,Elina Richardsdotter-Andersson et al.
Kahkashan Kamal et al.
Tolerogenic dendritic cells (tolDCs) that dampen T cell responses can be induced from blood monocytes in vitro using factors such as Vitamin D3 (VitD), dexamethasone, IL-10, or rapamycin. However, challenges remain in obtaining robust and e...
Administration of the NOD2 Agonist MDP Reduces Cryptosporidium parvum Infection in Neonatal Mice Through IL-22 Involvement [0.03%]
NOD2激动剂MDP的使用通过IL-22参与减少小鼠隐孢子虫感染
Mégane Fernandez,Tiffany Pezier,Julien Pichon et al.
Mégane Fernandez et al.
At birth, the mucosal immune system of neonates is not fully developed, making them more susceptible to respiratory and intestinal diseases. Previously described host-directed therapies using toll-like receptor (TLR) activation-based strate...
Zuyi Fu,Matevž Rumpret,Irina Kube-Golovin et al.
Zuyi Fu et al.
Activating immune receptors provides mechanisms for phagocytes to elicit important effector functions that promote the killing of microbes. Leukocyte immunoglobulin-like receptor A5 (LILRA5), an orphan immune receptor expressed by human pha...
Identification and Functional Validation of Novel Pathogenic Variants in Primary Immunodeficiencies [0.03%]
原发性免疫缺陷病致病基因变异的识别与功能验证
Arvinden Vr,Geeta Madathil Govindaraj,Aditya Ramdas Iyer et al.
Arvinden Vr et al.
Primary immunodeficiency diseases (PIDs) are inherited disorders caused by genetic defects affecting immune function, leading to recurrent infections, autoimmunity, and malignancies. Many PIDs remain genetically uncharacterized, largely due...
CD16A Shedding Regulates Innate Cell Engager-Induced Serial Killing by Natural Killer Cells [0.03%]
CD16A的脱落调节自然杀伤细胞介导的串行杀伤作用
Chiara Zambarda,Karolin Guldevall,Christian Breunig et al.
Chiara Zambarda et al.
Natural killer (NK) cells can protect from tumor-transformed cells using a fine-tuned machinery of activating and inhibiting receptors. An important activating receptor is Fc gamma receptor IIIa (FcγRIIIA or CD16A), which can trigger antib...
Short-Chain Fatty Acid Sodium Butyrate Suppresses Protective Humoral Immunity by Inhibiting Follicular T Helper Cell Differentiation [0.03%]
丁酸通过抑制滤泡辅助性T细胞分化来抑制保护性体液免疫响应
Bhushan Nikam,Someshwar Nath Jha,Yatish Thakare et al.
Bhushan Nikam et al.
The gut microbiome and its metabolites are critical regulators of intestinal homeostasis, with emerging evidence highlighting their influence on humoral immune responses and vaccine efficacy. The development of effective humoral immunity de...
TEAMwork: Interplay of Post-Transcriptional Mechanisms, Epigenetics and Metabolism in (Auto-)Immunity [0.03%]
后转录机制、表观遗传和代谢在免疫中的相互作用
Francesca Rossi,Martin Turner
Francesca Rossi
Changes in transcript abundance and isoforms, mediated by epigenetic and post-transcriptional mechanisms, are a hallmark of the development, activation, and effector functions of immune cells. How epigenetic and post-transcriptional process...
Purin Metabolism Is Crucial for Regulatory T Cell Stability and Function [0.03%]
嘌呤代谢对调节性T细胞的稳定性和功能至关重要
Young S Lee,Marina W Shirkey,Vikas Saxena et al.
Young S Lee et al.
Cellular metabolism intricately directs the differentiation, stability, and function of regulatory T cells (Tregs), which are pivotal in immune regulation. Metabolic reprogramming enables Tregs to adapt to diverse tissue environments; howev...
Anti-SARS-CoV-2 Spike IgA2 Induces Inflammation by Human Macrophages [0.03%]
抗SARS-CoV-2刺突IgA2通过人类巨噬细胞诱导炎症反应
Lynn Mes,Jennifer Veth,Julie Van Coillie et al.
Lynn Mes et al.
Severe COVID-19 is an immunological disorder characterized by a hyper-inflammatory reaction of the immune system. SARS-CoV-2 anti-spike antibodies of the IgG isotype are known to strongly contribute to this hyperinflammation by overactivati...