Systematic analysis of CD39, CD103, CD137, and PD-1 as biomarkers for naturally occurring tumor antigen-specific TILs [0.03%]
系统分析CD39、CD103、CD137和PD-1作为天然发生肿瘤特异性TIL生物标志物的能力
Monika A Eiva,Dalia K Omran,Jessica A Chacon et al.
Monika A Eiva et al.
The detection of tumor-specific T cells in solid tumors is integral to interrogate endogenous antitumor responses and to advance downstream therapeutic applications. Multiple biomarkers are reported to identify endogenous tumor-specific tum...
Phenotypic comparison of human alveolar macrophages before and after in vivo rhinovirus 16 challenge [0.03%]
人副流感病毒16型感染前后人体肺泡巨噬细胞的表型比较研究
Linsey E S de Groot,Paul Brinkman,Yanaika S Sabogal Piñeros et al.
Linsey E S de Groot et al.
We used mass cytometry to extensively characterize bronchoalveolar lavage macrophages before and two days after in vivo rhinovirus 16 infection in a heterogeneous population of healthy and asthma/COPD subjects. Multivariate partial least sq...
Comparative Study
European journal of immunology. 2021 Nov;51(11):2691-2693. DOI:10.1002/eji.202149222 2021
Correction [0.03%]
改正
Published Erratum
European journal of immunology. 2021 Sep;51(9):2351. DOI:10.1002/eji.202170099 2021
James Di Santo,Nadja Bakocevic
James Di Santo
MHC class I molecules co-stimulate NK1.1 signaling and enhance Ca2+ flux in murine NK cells [0.03%]
MHC-I分子通过NK1.1信号通路协同刺激小鼠NK细胞并增强其Ca2+流量
Sridharan Ganesan,Petter Höglund
Sridharan Ganesan
Simultaneous triggering of NK1.1 and MHC class I on NK cells gives a higher Ca2+ flux response compared to triggering the NK1.1 receptor alone. The data suggest a novel costimulatory role for MHC class I molecules on NK cell responses. ...
SARS-CoV-2-reactive T-cell receptors isolated from convalescent COVID-19 patients confer potent T-cell effector function [0.03%]
从新冠肺炎康复者体内分离的SARS-CoV-2反应性T细胞受体赋予强烈的T细胞效应功能
Fabian Brunk,Andreas Moritz,Annika Nelde et al.
Fabian Brunk et al.
Both B cells and T cells are involved in an effective immune response to SARS-CoV-2, the disease-causing virus of COVID-19. While B cells-with the indispensable help of CD4+ T cells-are essential to generate neutralizing antibodies, T cells...
Julie Deckers,Benjamin J Marsland,Erika von Mutius
Julie Deckers
The prevalence of asthma and other allergic diseases has rapidly increased in "Westernized" countries over recent decades. This rapid increase suggests the involvement of environmental factors, behavioral changes or lifestyle, rather than g...
Identification of the Fc-alpha/mu receptor in Xenopus provides insight into the emergence of the poly-Ig receptor (pIgR) and mucosal Ig transport [0.03%]
在非洲爪蟾中鉴定Fc-α/μ受体，为聚免疫球蛋白受体(pIgR)和黏膜Ig运输的出现提供见解
Emily M Flowers,Harold R Neely,Jacqueline Guo et al.
Emily M Flowers et al.
The polyimmunoglobulin receptor (pIgR) transcytoses J chain-containing antibodies through mucosal epithelia. In mammals, two cis-duplicates of PIGR, FCMR, and FCAMR, flank the PIGR gene. A PIGR duplication is first found in amphibians, prev...
Colostrum IgA1 antibodies recognize antigens from Helicobacter pylori and prevent cytoskeletal changesin human epithelial cells [0.03%]
初乳IgA1抗体识别Helicobacter pylori抗原并防止人类上皮细胞的细胞骨架变化
Shantal Lizbeth Baltierra-Uribe,Alejandra Montañez-Barragán,Héctor Romero-Ramírez et al.
Shantal Lizbeth Baltierra-Uribe et al.
Helicobacter pylori is a Gram-negative bacterium found on the luminal surface of the gastric mucosa in at least 50% of the world's human population. The protective effect of breastfeeding against H. pylori infection has been extensively rep...
αβ T cells replacing dermal and epidermal γδ T cells in Tcrd-/- mice express an MHC-independent TCR repertoire [0.03%]
Tcrd敲除小鼠中αβ T细胞替代真皮和表皮γδ T细胞并表达一种MHC非依赖性的TCR库
Christoph Binz,Anja Bubke,Inga Sandrock et al.
Christoph Binz et al.
The epidermis of mouse skin is usually populated by dendritic epidermal T cells (γδDETC) expressing an invariant Vγ5Vδ1+ TCR. In Tcrd-/- mice, skin-resident γδDETC are replaced by αβDETC carrying polyclonal αβ TCRs. Although they ...