Consent and confidentiality in the light of recent demands for data sharing [0.03%]
近期呼吁共享数据背景下的知情同意和保密问题
Garrath Williams,Iris Pigeot
Garrath Williams
Many attempts have been made to formalize ethical requirements for research. Among the most prominent mechanisms are informed consent requirements and data protection regimes. These mechanisms, however, sometimes appear as obstacles to rese...
Neil J Perkins,Emily M Mitchell,Robert H Lyles et al.
Neil J Perkins et al.
Pooled study designs, where individual biospecimens are combined prior to measurement via a laboratory assay, can reduce lab costs while maintaining statistical efficiency. Analysis of the resulting pooled measurements, however, often requi...
Improved nonparametric estimation of the optimal diagnostic cut-off point associated with the Youden index under different sampling schemes [0.03%]
不同抽样方案下与Youden指数相关的最优诊断截断值的改进非参数估计方法研究
Jingjing Yin,Hani Samawi,Daniel Linder
Jingjing Yin
A diagnostic cut-off point of a biomarker measurement is needed for classifying a random subject to be either diseased or healthy. However, the cut-off point is usually unknown and needs to be estimated by some optimization criteria. One im...
Methodological aspects of the benefit assessment of medical interventions [0.03%]
卫生技术评估中的效益评价方法学问题研究
Dieter Hauschke,Claudia Schmoor
Dieter Hauschke
Reproducible research in statistics: A review and guidelines for the Biometrical Journal [0.03%]
统计学中可复现性研究的回顾与Biometrical Journal指南建议事项
Benjamin Hofner,Matthias Schmid,Lutz Edler
Benjamin Hofner
Reproducible research (RR) constitutes the idea that a publication should be accompanied by all relevant material to reproduce the results and findings of a scientific work. Hence, results can be verified and researchers are able to build u...
Robust Bayesian hierarchical model using normal/independent distributions [0.03%]
基于normal/independent分布的稳健Bayesian层次模型
Geng Chen,Sheng Luo
Geng Chen
The multilevel item response theory (MLIRT) models have been increasingly used in longitudinal clinical studies that collect multiple outcomes. The MLIRT models account for all the information from multiple longitudinal outcomes of mixed ty...
Inference for low- and high-dimensional multigroup repeated measures designs with unequal covariance matrices [0.03%]
协方差矩阵不等的多组重复测量设计的低维和高维推断方法研究
Martin Happ,Solomon W Harrar,Arne C Bathke
Martin Happ
We propose tests for main and simple treatment effects, time effects, as well as treatment by time interactions in possibly high-dimensional multigroup repeated measures designs. The proposed inference procedures extend the work by Brunner ...
Josemar Rodrigues,Gauss M Cordeiro,Vicente G Cancho et al.
Josemar Rodrigues et al.
The purpose of this article is to make the standard promotion cure rate model (Yakovlev and Tsodikov, ) more flexible by assuming that the number of lesions or altered cells after a treatment follows a fractional Poisson distribution (Laski...
New class of Johnson SB distributions and its associated regression model for rates and proportions [0.03%]
Johnson SB分布的新类别及其相关的速率和比例回归模型
Artur J Lemonte,Jorge L Bazán
Artur J Lemonte
By starting from the Johnson SB distribution pioneered by Johnson (), we propose a broad class of distributions with bounded support on the basis of the symmetric family of distributions. The new class of distributions provides a rich sourc...
Chiu-Hsieh Hsu,Yulei He,Yisheng Li et al.
Chiu-Hsieh Hsu et al.
We consider the problem of estimating the marginal mean of an incompletely observed variable and develop a multiple imputation approach. Using fully observed predictors, we first establish two working models: one predicts the missing outcom...